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Tyk2 [p Tyr1055, p Tyr1054] Antibody - BSA Free

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Western Blot: Tyk2 [p Tyr1055, p Tyr1054] Antibody [NBP3-16896] - Western blot analysis of extracts of NIH/3T3 cells, using Tyk2 Rabbit pAb (NBP3-16896) at 1:1000 dilution.NIH/3T3 cells were treated by IFN-alpha (100 ng/ml) at 37C for 30 minutes after serum-starvation overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. Detection: ECL Enhanced Kit. Exposure time: 180s.
Western Blot: Tyk2 [p Tyr1055, p Tyr1054] Antibody [NBP3-16896] - Western blot analysis of extracts of NIH/3T3 cells, using Tyk2 Rabbit pAb (NBP3-16896) at 1:1000 dilution.NIH/3T3 cells were treated by IFN-alpha (100 ...read more

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

View Available Formulations
Catalog# & Formulation Size Price
BSA Free
NBP3-16896-20ul
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Tyk2 [p Tyr1055, p Tyr1054] Antibody - BSA Free Summary

Immunogen
A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2 (NP_003322.3). HEYYRV
Modification
p Tyr1054, p Tyr1055
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TYK2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500 - 1:1000
Theoretical MW
134 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Tyk2 [p Tyr1055, p Tyr1054] Antibody - BSA Free

  • EC 2.7.10
  • EC 2.7.10.2
  • JTK1
  • non-receptor tyrosine-protein kinase TYK2
  • Tyk2
  • tyrosine kinase 2

Background

Novel non-receptor tyrosine-protein kinase, Tyk2, belongs to the tyrosine protein kinase family and plays a role in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Tyk2 is believed to phosphorylate the interferon-alpha/beta receptor alpha chain (1). It has been shown that Tyk2 links the interferon alpha/beta receptor to the cytoplasmic transcription factor that mediates activation of interferon-responsive genes (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TYK2