STAT4 [p Tyr693] Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Signal transduction and activator of transcription 4 (STAT4) is a member of the Jak/STAT signal transduction pathway. STAT4 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, homo or heterodimerizes with other STAT proteins, which then translocate to the nucleus and activate transcription of specific genes. STAT4 is expressed in subset of tissues including spleen, heart, brain, peripheral blood cells and testis. STAT4 is involved in mediating IL-12 response in lymphocytes and regulating T helper cell differentiation.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: Flow Cytometry, Western Blot.

Showing Publications 1 - 4 of 4.

Publications using AF4319	Applications	Species
Jammy Mariotton, Anette Sams, Emmanuel Cohen, Alexis Sennepin, Gabriel Siracusano, Francesca Sanvito et al. Native CGRP Neuropeptide and Its Stable Analogue SAX, But Not CGRP Peptide Fragments, Inhibit Mucosal HIV-1 Transmission Frontiers in Immunology 12/8/2021 [PMID: 34956215]
Yu S, Zhang Y, Yang B, Wu C Human memory, but not naive, CD4+ T cells expressing transcription factor T-bet might drive rapid cytokine production. J Biol Chem, 2014-11-05;289(51):35561-9. 2014-11-05 [PMID: 25378399] (Western Blot, Human)	Western Blot	Human
Wang X, Bishop KA, Hegde S, Rodenkirch LA, Pike JW, Gumperz JE Human invariant natural killer T cells acquire transient innate responsiveness via histone H4 acetylation induced by weak TCR stimulation. J. Exp. Med., 2012-04-16;209(5):987-1000. 2012-04-16 [PMID: 22508835] (Flow Cytometry, Human)	Flow Cytometry	Human
Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis. J. Immunol., 2008-07-15;181(2):1491-8. 2008-07-15 [PMID: 18606704] (Western Blot, Mouse)	Western Blot	Mouse

Array AF4319

• STAT4 Antibodies
• STAT4 Lysate
• STAT4 Proteins