Request a Print Copy of This Poster The TGF beta pathway is involved in the regulations of cellular proliferation, differentiation, embryogenesis and apoptosis. TGF beta binds its Receptor Type II which then phosphorylates the TGF beta Receptor Type I. The activated Receptor I can then phosphorylate various SMAD molecules which accumulate in the nucleus and act as transcription factors. The TGF beta is also involved in inflammation, immunity and cancer pathways. Find available products by clicking on key proteins in the TGF-beta interactive pathway below. |
Request a Print Copy of This Poster Explore Your Pathways with Novus’ Laverne! This free bioinformatics tool is designed to facilitate scientific exploration of related genes, diseases and pathways based on co-citations. |