Species: Hu
Applications: WB
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: AC
Description
Novel non-receptor tyrosine-protein kinase, Tyk2, belongs to the tyrosine protein kinase family and plays a role in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Tyk2 is believed to phosphorylate the interferon-alpha/beta receptor alpha chain (1). It has been shown that Tyk2 links the interferon alpha/beta receptor to the cytoplasmic transcription factor that mediates activation of interferon-responsive genes (2).
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
7297 |
| Alternate Names |
- EC 2.7.10
- EC 2.7.10.2
- JTK1
- non-receptor tyrosine-protein kinase TYK2
- tyrosine kinase 2
|
Research Areas for Tyk2
Find related products by research area and learn more about each of the different research areas below.
Phospho-SpecificProtein Kinase
![Western Blot Tyk2 Antibody (307214) [Unconjugated]](http://images.novusbio.com/fullsize2/Tyk2_MAB3427_Western_Blot_6105.jpg)
