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Tyk2 Antibody - BSA Free

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Western Blot: Tyk2 Antibody [NBP1-87825] - Analysis in human cell line RT-4.
Western Blot: Tyk2 Antibody [NBP1-87825] - Analysis in human cell line RT-4.
Immunocytochemistry/ Immunofluorescence: Tyk2 Antibody [NBP1-87825] - Staining of human cell line U-2 OS shows localization to cytosol. Antibody staining is shown in green.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

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Catalog# & Formulation Size Price
BSA Free
NBP1-87825-25ul
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Tyk2 Antibody - BSA Free Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: RFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAFGQPADRPREPLWAYFCDFRDITHVV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TYK2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Western Blot 0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
Tyk2 Protein (NBP1-87825PEP)
Publications
Read Publication using NBP1-87825.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Tyk2 Antibody - BSA Free

  • EC 2.7.10
  • EC 2.7.10.2
  • JTK1
  • non-receptor tyrosine-protein kinase TYK2
  • Tyk2
  • tyrosine kinase 2

Background

Novel non-receptor tyrosine-protein kinase, Tyk2, belongs to the tyrosine protein kinase family and plays a role in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Tyk2 is believed to phosphorylate the interferon-alpha/beta receptor alpha chain (1). It has been shown that Tyk2 links the interferon alpha/beta receptor to the cytoplasmic transcription factor that mediates activation of interferon-responsive genes (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Tyk2 Antibody (NBP1-87825)(1)


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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

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Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...  Read full blog post.
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Bioinformatics

Gene Symbol TYK2