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STAT2 [p Tyr689] Antibody (1021D) [Alexa Fluor® 488]

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Daudi human Burkitt's lymphoma cells were serum starved ovenight, then left untreated (open histogram) or treated with 500 U/mL Recombinant Human IFN-aA (11100-1) for 20 minutes was stained with Rabbit Anti-Human STAT2 Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # IC8627G, filled histogram) or isotype control antibody (IC105G, not shown). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (FC004) and permeabilized with 90% methanol. View our protocol for Staining Intracellular Molecules.
Daudi human Burkitt's lymphoma cells were serum starved ovenight, then left untreated (open histogram) or treated with 500 U/mL Recombinant Human IFN-aA (11100-1) for 20 minutes was stained with Rabbit Anti-Human STAT2 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
1021D
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC2890U-100UG
Alexa Fluor 405
IC2890V-100UG
Alexa Fluor 532
FAB2890X
Alexa Fluor 594
IC2890T-100UG
Alexa Fluor 647
IC2890R-100UG
Alexa Fluor 700
IC2890N-100UG
Alexa Fluor 750
IC2890S-100UG
Allophycocyanin
FAB2890A
Allophycocyanin/Cy7
FAB2890APCCY7
Biotin
FAB2890B
CoraFluor 1
FAB2890CL1
DyLight 350
FAB2890D
DyLight 405
FAB2890E
DyLight 488
FAB2890K
DyLight 550
FAB2890L
DyLight 594
FAB2890M
DyLight 650
FAB2890W
DyLight 680
FAB2890Y
DyLight 755
FAB2890Z
FITC
FAB2890F
HRP
FAB2890H
Janelia Fluor 525
FAB2890JF525
Janelia Fluor 549
FAB2890I
Janelia Fluor 646
FAB2890J
Janelia Fluor 669
FAB2890JF669
PE
FAB2890P
PE/Atto594
FAB2890PEATT594
PE/Cy5.5
FAB2890PECY55
PE/Cy7
FAB2890PECY7
PerCP
FAB2890C
Unconjugated
MAB2890
mFluor Violet 450 SE
FAB2890MFV450
mFluor Violet 500 SE
FAB2890MFV500
mFluor Violet 610 SE
FAB2890MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB2890
Carrier Free
MAB2890
Carrier Free
MAB2890-SP
Carrier Free
IC2890V-100UG
Carrier Free
IC2890U-100UG
Carrier Free
IC2890T-100UG
Carrier Free
IC2890S-100UG
Carrier Free
IC2890R-100UG
Carrier Free
IC2890N-100UG
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STAT2 [p Tyr689] Antibody (1021D) [Alexa Fluor® 488] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Phosphopeptide containing the human STAT2 Y690 site
Modification
p Tyr689
Specificity
Detects human phospho-STAT2 (Y690) in Western blots.
Source
N/A
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
STAT2
Purity Statement
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 5 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for STAT2 [p Tyr689] Antibody (1021D) [Alexa Fluor® 488]

  • interferon alpha induced transcriptional activator
  • ISGF-3
  • MGC59816
  • P113
  • signal transducer and activator of transcription 2
  • signal transducer and activator of transcription 2, 113kD
  • signal transducer and activator of transcription 2, 113kDa
  • STAT113
  • STAT2

Background

STAT2 (signal transducer and activator of transcription 2) is a 113 kDa member of the STAT family of cytoplasmic transcription factors. STAT members generally mediate cytokine, growth factor and hormone receptor signal transduction. STAT2 is associated with type I ( alpha - and beta -) interferon signaling. All STATs contain an N‑terminal oligomerization domain, a DNA-binding domain, and an SH2-association region. STAT2 is phosphorylated at Y690 by receptor-associated Janus kinases (JAKs) leading to STAT2 dimerization and subsequent translocation to the nucleus to activate gene transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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STAT2 [p Tyr689] Antibody (1021D) [Alexa Fluor® 488]
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Bioinformatics

Gene Symbol STAT2