Lysyl Oxidase Homolog 2/LOXL2 Antibody (JU32-53) Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
Synthetic peptide within C-terminal human Lysyl Oxidase Homolog 2/LOXL2. (SwissProt: Q9Y4K0 Human; SwissProt: P58022 Mouse; SwissProt: B5DF27 Rat) |
Localization |
Secreted, Nucleus. |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
LOXL2 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1:50-1:100
- Immunocytochemistry/ Immunofluorescence 1:50-1:200
- Immunohistochemistry
- Immunohistochemistry-Paraffin 1:50-1:100
- Western Blot 1:500-1:2000
|
Theoretical MW |
87 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
TBS (pH7.4), 0.05% BSA, 40% Glycerol |
Preservative |
0.05% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Protein A purified |
Alternate Names for Lysyl Oxidase Homolog 2/LOXL2 Antibody (JU32-53)
Background
LOXL2 encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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