LOXL1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 4 applications: IF/IHC, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, WB.

Showing Publications 1 - 6 of 6.

Publications using H00004016-D01P	Applications	Species
Jiang C, Wang M, Yao W et al. Comprehensive Analysis on Prognosis and Immune Infiltration of Lysyl Oxidase Family Members in Pancreatic Adenocarcinoma With Experimental Verification Frontiers in Molecular Biosciences 2022-04-01 [PMID: 35433829] (Immunohistochemistry)	Immunohistochemistry
De Maria A, Zientek KD, David LL et al. Compositional Analysis of Extracellular Aggregates in the Eyes of Patients With Exfoliation Syndrome and Exfoliation Glaucoma Investigative Opthalmology & Visual Science 2021-12-29 [PMID: 34964803] (Immunocytochemistry/ Immunofluorescence)	Immunocytochemistry/ Immunofluorescence
Qingjiang H, Takaaki M, Shotaro K et al. Potential association of LOXL1 with peritoneal dissemination in gastric cancer possibly via promotion of EMT. PLoS One. 2020-10-23 [PMID: 33095806]
Yu H, Ding J, Zhu H et al. LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2 Cell Death Differ. 2020-05-18 [PMID: 32424143] (IF/IHC, WB, Human, Mouse)	IF/IHC, WB	Human, Mouse
Sethi A, Wordinger RJ, Clark AF. Gremlin utilizes canonical and non-canonical TGFbeta signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells. Exp Eye Res. 2013-08-01 [PMID: 23748100] (WB, Human)	WB	Human
Sethi A, Mao W, Wordinger RJ, Clark AF. Transforming Growth Factor Beta Induces Extracellular Matrix Protein Crosslinking Lysyl Oxidase (LOX) Genes in Human Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2011-05-05 [PMID: 21546528]

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Leah Perkins	Simple Western	Human	12/06/2022	View Summary Application Simple Western Sample Tested hep3b cell line Species Human Lot N/A Comments Comments ***Novus Innovators Program - new species or application used on a primary antibody.*** Test Ab: LOX-L1 Ab Cat#H00004016-D01P, NOVUS Sample: Hep3B cell line Simple protein (Jess): 12-230 kda seperation modules. Best Protein Lysate concentration: 1mg/ml Best Primary Ab dilution: 1:10 Secondary – Rabbit HRP

Array H00004016-D01P

• LOXL1 Antibodies
• LOXL1 ELISA Kits
• LOXL1 Lysate