Western Blot: GABA Transporter 2 Antibody [NB100-1872] - Levels of identified proteins in RPE lysates.Both young (2 months) and old (24 months) RPE cells were harvested, lysed. 20 ug of protein of each sample was ...read more
Western Blot: GABA Transporter 2 Antibody [NB100-1872] - Analysis of GABA 2 levels in 20 ug of young and old RPE cell lysates. [PMID: 22701690]
Levels of identified proteins in RPE lysates.Both young (2 months) and old (24 months) RPE cells were harvested, lysed. 20 µg of protein of each sample was separated on a 4–20% SDS gel, transferred to PVDF membranes ...read more
Cross-reacts with Human, Mouse, Rat and Chicken (see review). Not yet tested in other species.
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Antiserum
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Lyophilized powder, reconstituted in distilled water.
Alternate Names for GABA Transporter 2 Antibody
GABA transport protein
GAT-2
GAT2Solute carrier family 6 member 13
sodium- and chloride-dependent GABA transporter 2
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
Background
GABA is a major inhibitory neurotransmitter and the GABAergic transmission is terminated by the rapid Na+/Cl-dependent uptake of through GABA transporters. There are multiple subtypes of GABA transporters (GAT1, GAT2, GAT3; and betaine GABA transporter (BGT-1). There is 50percent homology between each subtypes. GAT1 and GAT3 have been detected in various parts of the brain while GAT2 is found in many tissues. It appears that GAT1 and GAT3 are involved in distinct GABAergic transmission while GAT2 may be important in non-neural functions. GAT2 is a gamma-amino butyric acid (GABA) transporter. It is a 602 amino acid (85kDa) transmembrane protein
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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