GABA Transporter 2 Products

Description

GABA is a major inhibitory neurotransmitter and the GABAergic transmission is terminated by the rapid Na+/Cl-dependent uptake of through GABA transporters. There are multiple subtypes of GABA transporters (GAT1, GAT2, GAT3; and betaine GABA transporter (BGT-1). There is ~50% homology between each subtypes. GAT1 and GAT3 have been detected in various parts of the brain while GAT2 is found in many tissues. It appears that GAT1 and GAT3 are involved in distinct GABAergic transmission while GAT2 may be important in non-neural functions. GAT2 is a gamma-amino butyric acid (GABA) transporter. It is a 602 amino acid (85kDa) transmembrane protein

Bioinformatics

Entrez	171163 Rat 6540 Human
Uniprot	NP_057699.2 Human P31646 Rat
Product By Gene ID	6540
Alternate Names	GABA transport protein GAT-2 GAT2Solute carrier family 6 member 13 sodium- and chloride-dependent GABA transporter 2 solute carrier family 6 (neurotransmitter transporter, GABA), member 13

Research Areas for GABA Transporter 2

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Neuroscience