CXCR6 Antibody - BSA Free

Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use other chemokine receptors, such as CXCR6, a T-lymphocyte-expressed seven-transmembrane domain receptor that mediates fusion, entry, and trafficking of tumor-infiltrating lymphocytes. CXCR6 has been identified in human blood (T-lymphocytes, activated peripheral blood lymphocytes, monocyte-derived dendritic cells, primitive cord blood cells), placental trophoblasts, T-lymphocytes and dendritic cells in the skin, lymphoid tissues, and in fetal brain astrocytes. ESTs have been isolated from human normal placenta, liver/spleen, and pregnant uterus libraries, and human cancer kidney and uterus libraries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: FLOW, ICC/IF.

Showing Publications 1 - 4 of 4.

Publications using NLS1102	Applications	Species
Qu J, Wu B, Chen L et Al. CXCR6-positive circulating mucosal-associated invariant T cells can identify patients with non-small cell lung cancer responding to anti-PD-1 immunotherapy J Exp Clin Cancer Res 2024-05-03 [PMID: 38698468]
Binglin Wang, Yi Wang, Xiaofan Sun, Guoliang Deng, Wei Huang, Xingxin Wu et al. CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell Journal for ImmunoTherapy of Cancer 2021-08-29 [PMID: 34462326]
Behnan J, Isakson P, Joel M et al. Recruited brain tumor-derived mesenchymal stem cells contribute to brain tumor progression. Stem Cells. 2013-12-03 [PMID: 24302539] (FLOW, Human)	FLOW	Human
Jung Y, Kim JK, Shiozawa Y et al. Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis. Nat Commun 2013-01-01 [PMID: 23653207] (ICC/IF, Mouse, Human)	ICC/IF	Mouse, Human

Array NLS1102

• CXCR6 Antibodies
• CXCR6 ELISA Kits
• CXCR6 Protein