Name: CCR3 Antibody (61828)
Brand: Novus Biologicals
SKU: MAB155
Price: 479 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	Flow, IHC, B/N, CyTOF-ready
Clone	61828
Clonality	Monoclonal
Host	Rat
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 FAB155U-100UG

Alexa Fluor 405 FAB155V-100UG

Alexa Fluor 488 FAB155G-100UG

Alexa Fluor 532 FAB155X

Alexa Fluor 594 FAB155T-100UG

Alexa Fluor 647 FAB155R-100UG

Alexa Fluor 750 FAB155S-100UG

Allophycocyanin FAB155A-100

Allophycocyanin FAB155A-025

Allophycocyanin/Cy7 FAB155APCCY7

Biotin FAB155B

DyLight 350 FAB155D

DyLight 405 FAB155E

DyLight 488 FAB155K

DyLight 550 FAB155L

DyLight 594 FAB155M

DyLight 650 FAB155W

DyLight 680 FAB155Y

DyLight 755 FAB155Z

Fluorescein FAB155F-100

Fluorescein FAB155F-025

HRP FAB155H

Janelia Fluor 549 FAB155I

Janelia Fluor 646 FAB155J

PE/Atto594 FAB155PEATT594

PE/Cy5.5 FAB155PECY55

PE/Cy7 FAB155PECY7

PerCP (Peridinin-chlorophyll Protein Complex) FAB155C-025

PerCP (Peridinin-chlorophyll Protein Complex) FAB155C-100

Phycoerythrin FAB155P-100

Phycoerythrin FAB155P-025

mFluor Violet 450 SE FAB155MFV450

mFluor Violet 500 SE FAB155MFV500

mFluor Violet 610 SE FAB155MFV610

Catalog# & Formulation	Size	Price
Carrier Free FAB155R-100UG

Carrier Free FAB155S-100UG

Carrier Free FAB155T-100UG

Carrier Free FAB155U-100UG

Carrier Free FAB155V-100UG

Carrier Free MAB155-SP

Carrier Free FAB155P-100

Carrier Free FAB155A-025

Carrier Free FAB155P-025

Carrier Free FAB155F-100

Carrier Free FAB155F-025

Carrier Free FAB155C-100

Carrier Free FAB155C-025

Carrier Free FAB155A-100

Carrier Free FAB155G-100UG

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB155U-100UG
Alexa Fluor 405	FAB155V-100UG
Alexa Fluor 488	FAB155G-100UG
Alexa Fluor 532	FAB155X
Alexa Fluor 594	FAB155T-100UG
Alexa Fluor 647	FAB155R-100UG
Alexa Fluor 750	FAB155S-100UG
Allophycocyanin	FAB155A-025
Allophycocyanin	FAB155A-100
Allophycocyanin/Cy7	FAB155APCCY7
Biotin	FAB155B
DyLight 350	FAB155D
DyLight 405	FAB155E
DyLight 488	FAB155K
DyLight 550	FAB155L
DyLight 594	FAB155M
DyLight 650	FAB155W
DyLight 680	FAB155Y
DyLight 755	FAB155Z
Fluorescein	FAB155F-100
Fluorescein	FAB155F-025
HRP	FAB155H
Janelia Fluor 549	FAB155I
Janelia Fluor 646	FAB155J
PE/Atto594	FAB155PEATT594
PE/Cy5.5	FAB155PECY55
PE/Cy7	FAB155PECY7
PerCP (Peridinin-chlorophyll Protein Complex)	FAB155C-025
PerCP (Peridinin-chlorophyll Protein Complex)	FAB155C-100
Phycoerythrin	FAB155P-100
Phycoerythrin	FAB155P-025
mFluor Violet 450 SE	FAB155MFV450
mFluor Violet 500 SE	FAB155MFV500
mFluor Violet 610 SE	FAB155MFV610

CCR3 Antibody (61828)

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CCR3 Antibody (61828) Summary

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Publications for CCR3 Antibody (MAB155)(20)

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Bioinformatics

Additional Information	Clone 61828 was used by HLDA to establish CD designation
Immunogen	Y3 rat myeloid cell line transfected with human CCR3 Accession # P51677
Specificity	Detects human CCR3 transfectants in flow cytometry. In flow cytometry, no cross-reactivity with CCR1, CCR2, CCR5, and CCR6 transfectants or the parental cell line is observed. Detects CCR3 on peripheral blood eosinophils.
Source	N/A
Isotype	IgG2a
Clonality	Monoclonal
Host	Rat
Gene	CCR3
Purity	Protein A or G purified from hybridoma culture supernatant
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Purity	Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Publications using MAB155	Applications	Species
Y Kaibori, D Nagakubo CCR3 blockage elicits polyploidization associated with the signatures of epithelial-mesenchymal transition in carcinoma cell lines Cancer Gene Therapy, 2022-09-19;0(0):. 2022-09-19 [PMID: 36123391] (ICC, Human)	ICC	Human
MC Mladinich, JN Conde, WR Schutt, SY Sohn, ER Mackow Blockade of Autocrine CCL5 Responses Inhibits Zika Virus Persistence and Spread in Human Brain Microvascular Endothelial Cells MBio, 2021-08-17;12(4):e0196221. 2021-08-17 [PMID: 34399621] (Neutralization, Human)	Neutralization	Human
Michal Segal-Salto, Neta Barashi, Avi Katav, Vicktoria Edelshtein, Arnon Aharon, Sharon Hashmueli et al. A blocking monoclonal antibody to CCL24 alleviates liver fibrosis and inflammation in experimental models of liver damage JHEP Reports 2020-02-01 [PMID: 32039405]
Evidence for chemokine synergy during neutrophil migration in ARDS Thorax, 2016-08-05;0(0):. 2016-08-05 [PMID: 27496101] (Flow Cytometry, Human)	Flow Cytometry	Human
Guichun Huang Hypoxia induced CCL28 promotes angiogenesis in lung adenocarcinoma by targeting CCR3 on endothelial cells Sci Rep, 2016-06-02;6(0):27152. 2016-06-02 [PMID: 27250766] (Neutralization, Human)	Neutralization	Human
Expression and prognostic significance of CCL11/CCR3 in glioblastoma Oncotarget, 2016-05-31;7(22):32617-27. 2016-05-31 [PMID: 27119233] (IHC-P, Human)	IHC-P	Human
Facciabene A, Peng X, Hagemann IS, Balint K, Barchetti A, Wang LP, Gimotty PA, Gilks CB, Lal P, Zhang L, Coukos G Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature, 2011-07-13;475(7355):226-30. 2011-07-13 [PMID: 21753853] (Neutralization, Mouse)	Neutralization	Mouse
Jung DW, Che ZM, Kim J, Kim K, Kim KY, Williams D, Kim J Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7. Int. J. Cancer, 2010-07-15;127(2):332-44. 2010-07-15 [PMID: 19937793] (Neutralization, Human)	Neutralization	Human
Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J. Immunol., 2008-12-01;181(11):8053-67. 2008-12-01 [PMID: 19017998] (Flow Cytometry, ICC, IHC-P, Neutralization, Human)	Flow Cytometry, ICC, IHC-P, Neutralization	Human
Ponte AL, Marais E, Gallay N, Langonne A, Delorme B, Herault O, Charbord P, Domenech J The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells, 2007-03-29;25(7):1737-45. 2007-03-29 [PMID: 17395768] (Flow Cytometry, Human)	Flow Cytometry	Human
Yuan Q, Campanella GS, Colvin RA, Hamilos DL, Jones KJ, Mathew A, Means TK, Luster AD Membrane-bound eotaxin-3 mediates eosinophil transepithelial migration in IL-4-stimulated epithelial cells. Eur. J. Immunol., 2006-10-01;36(10):2700-14. 2006-10-01 [PMID: 16983721] (Neutralization, Human)	Neutralization	Human
Beck LA, Tancowny B, Brummet ME, Asaki SY, Curry SL, Penno MB, Foster M, Bahl A, Stellato C Functional analysis of the chemokine receptor CCR3 on airway epithelial cells. J. Immunol., 2006-09-01;177(5):3344-54. 2006-09-01 [PMID: 16920975] (IHC-P, Human)	IHC-P	Human
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin. Immunol., 2006-06-16;120(2):220-31. 2006-06-16 [PMID: 16782408] (Neutralization, Human)	Neutralization	Human
Spencer LA, Melo RC, Perez SA, Bafford SP, Dvorak AM, Weller PF Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion. Proc. Natl. Acad. Sci. U.S.A., 2006-02-21;103(9):3333-8. 2006-02-21 [PMID: 16492782] (Flow Cytometry, Human)	Flow Cytometry	Human
Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts. J. Allergy Clin. Immunol., 2005-12-02;117(1):103-10. 2005-12-02 [PMID: 16387592] (IHC, Human)	IHC	Human
Kohrgruber N, Groger M, Meraner P, Kriehuber E, Petzelbauer P, Brandt S, Stingl G, Rot A, Maurer D Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. J. Immunol., 2004-12-01;173(11):6592-602. 2004-12-01 [PMID: 15557149] (Flow Cytometry, Human)	Flow Cytometry	Human
Annels NE, Willemze AJ, van der Velden VH, Faaij CM, van Wering E, Sie-Go DM, Egeler RM, van Tol MJ, RÃƒÂ©vÃƒÂ©sz T Possible link between unique chemokine and homing receptor expression at diagnosis and relapse location in a patient with childhood T-ALL. Blood, 2003-12-04;103(7):2806-8. 2003-12-04 [PMID: 14656893] (Flow Cytometry, Human)	Flow Cytometry	Human
Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J. Leukoc. Biol., 2003-05-01;73(5):584-90. 2003-05-01 [PMID: 12714572] (Flow Cytometry, Human)	Flow Cytometry	Human
Howard OM, Dong HF, Yang D, Raben N, Nagaraju K, Rosen A, Casciola-Rosen L, Hartlein M, Kron M, Yiadom K, Dwivedi S, Plotz PH, Oppenheim JJ Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells. J. Exp. Med., 2002-09-16;196(6):781-91. 2002-09-16 [PMID: 12235211] (IHC-Fr, Human)	IHC-Fr	Human
de Lavareille A, Roufosse F, Schandene L, Stordeur P, Cogan E, Goldman M Clonal Th2 cells associated with chronic hypereosinophilia: TARC-induced CCR4 down-regulation in vivo. Eur. J. Immunol., 2001-04-01;31(4):1037-46. 2001-04-01 [PMID: 11298328] (Flow Cytometry, Human)	Flow Cytometry	Human
Show All 20 Publications. Collapse Publications.

Gene Symbol	CCR3
Uniprot	P51677()