Name: CCR4 Antibody (205410) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB1567
Price: 489 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	Flow, CyTOF-ready
Clone	205410
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 FAB1567U-100UG

Alexa Fluor 405 FAB1567V-100UG

Alexa Fluor 488 FAB1567G-025

Alexa Fluor 532 FAB1567X

Alexa Fluor 594 FAB1567T-100UG

Alexa Fluor 647 FAB1567R-100

Alexa Fluor 647 FAB1567R-025

Alexa Fluor 700 FAB1567N-100UG

Alexa Fluor 750 FAB1567S-100UG

Allophycocyanin FAB1567A-025

Allophycocyanin FAB1567A-100

Allophycocyanin/Cy7 FAB1567APCCY7

Biotin FAB1567B

DyLight 350 FAB1567D

DyLight 405 FAB1567E

DyLight 488 FAB1567K

DyLight 550 FAB1567L

DyLight 594 FAB1567M

DyLight 650 FAB1567W

DyLight 680 FAB1567Y

DyLight 755 FAB1567Z

Fluorescein FAB1567F-025

Fluorescein FAB1567F-100

HRP FAB1567H

Janelia Fluor 549 FAB1567I

Janelia Fluor 646 FAB1567J

PE/Atto594 FAB1567PEATT594

PE/Cy5.5 FAB1567PECY55

PE/Cy7 FAB1567PECY7

PerCP (Peridinin-chlorophyll Protein Complex) FAB1567C-100

PerCP (Peridinin-chlorophyll Protein Complex) FAB1567C-025

Phycoerythrin FAB1567P-100

Phycoerythrin FAB1567P-025

mFluor Violet 450 SE FAB1567MFV450

mFluor Violet 500 SE FAB1567MFV500

mFluor Violet 610 SE FAB1567MFV610

Catalog# & Formulation	Size	Price
Carrier Free FAB1567G-025

Carrier Free FAB1567S-100UG

Carrier Free FAB1567T-100UG

Carrier Free FAB1567U-100UG

Carrier Free FAB1567V-100UG

Carrier Free FAB1567R-100

Carrier Free MAB1567-500

Carrier Free FAB1567R-025

Carrier Free FAB1567C-025

Carrier Free MAB1567-SP

Carrier Free FAB1567A-100

Carrier Free FAB1567A-025

Carrier Free FAB1567P-100

Carrier Free FAB1567P-025

Carrier Free FAB1567F-100

Carrier Free FAB1567F-025

Carrier Free FAB1567C-100

Carrier Free FAB1567N-100UG

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB1567U-100UG
Alexa Fluor 405	FAB1567V-100UG
Alexa Fluor 488	FAB1567G-025
Alexa Fluor 532	FAB1567X
Alexa Fluor 594	FAB1567T-100UG
Alexa Fluor 647	FAB1567R-100
Alexa Fluor 647	FAB1567R-025
Alexa Fluor 700	FAB1567N-100UG
Alexa Fluor 750	FAB1567S-100UG
Allophycocyanin	FAB1567A-025
Allophycocyanin	FAB1567A-100
Allophycocyanin/Cy7	FAB1567APCCY7
Biotin	FAB1567B
DyLight 350	FAB1567D
DyLight 405	FAB1567E
DyLight 488	FAB1567K
DyLight 550	FAB1567L
DyLight 594	FAB1567M
DyLight 650	FAB1567W
DyLight 680	FAB1567Y
DyLight 755	FAB1567Z
Fluorescein	FAB1567F-025
Fluorescein	FAB1567F-100
HRP	FAB1567H
Janelia Fluor 549	FAB1567I
Janelia Fluor 646	FAB1567J
PE/Atto594	FAB1567PEATT594
PE/Cy5.5	FAB1567PECY55
PE/Cy7	FAB1567PECY7
PerCP (Peridinin-chlorophyll Protein Complex)	FAB1567C-100
PerCP (Peridinin-chlorophyll Protein Complex)	FAB1567C-025
Phycoerythrin	FAB1567P-100
Phycoerythrin	FAB1567P-025
mFluor Violet 450 SE	FAB1567MFV450
mFluor Violet 500 SE	FAB1567MFV500
mFluor Violet 610 SE	FAB1567MFV610

CCR4 Antibody (205410) [Unconjugated]

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CCR4 Antibody (205410) [Unconjugated] Summary

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Alternate Names for CCR4 Antibody (205410) [Unconjugated]

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Publications for CCR4 Antibody (MAB1567)(27)

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Bioinformatics

Additional Information	Clone 205410 was used by HLDA to establish CD designation
Immunogen	Human CCR4 transfectants Met1-Leu360 Accession # P51679
Specificity	Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects CCR4 on human PBLs and platelets.
Source	N/A
Isotype	IgG2b
Clonality	Monoclonal
Host	Mouse
Gene	CCR4
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Publications using MAB1567	Applications	Species
Nicholas A. Vitanza, Ashley L. Wilson, Wenjun Huang, Kristy Seidel, Christopher Brown, Joshua A. Gustafson et al. Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety Cancer Discovery 1/9/2023 [PMID: 36259971]
Y Fang, W Fan, X Xu, AK Janoshazi, DC Fargo, X Li SIRT1 regulates cardiomyocyte alignment during maturation Journal of Cell Science, 2022-04-01;0(0):. 4/1/2022 [PMID: 35260907]
Angeline Rouers, Melissa Hui Yen Chng, Bernett Lee, Menaka P. Rajapakse, Kaval Kaur, Ying Xiu Toh et al. Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection Cell Reports Medicine 5/18/2021 [PMID: 34095880]
Matthew D Galbraith, Kohl T Kinning, Kelly D Sullivan, Ryan Baxter, Paula Araya, Kimberly R Jordan et al. Seroconversion stages COVID19 into distinct pathophysiological states eLife 3/16/2021 [PMID: 33724185]
MH Nelson, HM Knochelman, SR Bailey, LW Huff, JS Bowers, K Majchrzak-, MM Wyatt, MP Rubinstein, S Mehrotra, MI Nishimura, KE Armeson, PG Giresi, MJ Zilliox, HE Broxmeyer, CM Paulos Identification of human CD4+ T cell populations with distinct antitumor activity Science Advances, 2020-07-01;6(27):. 2020-07-01 [PMID: 32937437] (Flow Cytometry, Human)	Flow Cytometry	Human
Conor N. Gruber, Jorg J.A. Calis, Sofija Buta, Gilad Evrony, Jerome C. Martin, Skyler A. Uhl et al. Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function Immunity 9/1/2020 [PMID: 32750333]
M Martin-Fer, M Bravo Garc, C Gruber, S Murias Loz, MNH Malik, F Alsohime, A Alakeel, R Valdez, S Buta, G Buda, MA Marti, M Larralde, B Boisson, M Feito Rodr, X Qiu, M Chrabieh, M Al Ayed, S Al Muhsen, JV Desai, EMN Ferre, SD Rosenzweig, B Amador-Bor, LY Bravo-Gall, R Olmer, S Merkert, M Bret, AK Sood, A Al-Rabiaah, MH Temsah, R Halwani, M Hernandez, F Pessler, JL Casanova, J Bustamante, MS Lionakis, D Bogunovic Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions Cell Rep, 2020-05-12;31(6):107633. 2020-05-12 [PMID: 32402279] (CyTof, Human)	CyTof	Human
D Michlmayr, EY Kim, AH Rahman, R Raghunatha, S Kim-Schulz, Y Che, S Kalayci, ZH Gümü?, G Kuan, A Balmaseda, A Kasarskis, SM Wolinsky, M Suaréz-Far, E Harris Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection Cell Rep, 2020-04-28;31(4):107569. 2020-04-28 [PMID: 32348760] (CyTof, Human)	CyTof	Human
Guan-Da Syu, Shih-Chin Wang, Guangzhong Ma, Shuang Liu, Donna Pearce, Atish Prakash et al. Development and application of a high-content virion display human GPCR array Nature Communications 4/30/2019 [PMID: 31040288]
NM Bath, X Ding, NA Wilson, BM Verhoven, BA Boldt, A Sukhwal, SR Reese, SE Panzer, A Djamali, RR Redfield Desensitization and treatment with APRIL/BLyS blockade in rodent kidney transplant model PLoS ONE, 2019-02-08;14(2):e0211865. 2019-02-08 [PMID: 30735519] (Flow Cytometry, Rat)	Flow Cytometry	Rat
Evan W Newell Optimization of mass cytometry sample cryopreservation after staining Cytometry A, 2016-10-31;0(0):. 2016-10-31 [PMID: 27798817] (CyTof, Human)	CyTof	Human
Kap , Yolanda, van Driel , Nikki, Laman , Jon D, Tak , Paul P, 't Hart , Bert A CD20+ B cell depletion alters T cell homing. J Immunol, 2014-04-02;192(9):4242-53. 2014-04-02 [PMID: 24696233] (Flow Cytometry, Marmoset)	Flow Cytometry	Marmoset
Aruga A, Takeshita N, Kotera Y, Okuyama R, Matsushita N, Ohta T, Takeda K, Yamamoto M Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer. Clin Cancer Res, 2013-03-11;19(8):2224-31. 2013-03-11 [PMID: 23479678] (Flow Cytometry, Human)	Flow Cytometry	Human
Duluc , D, Gannevat , J, Anguiano , E, Zurawski , S, Carley , M, Boreham , M, Stecher , J, Dullaers , M, Banchereau , J, Oh , S Functional diversity of human vaginal APC subsets in directing T-cell responses. Mucosal Immunol, 2012-11-07;6(3):626-38. 2012-11-07 [PMID: 23131784] (Flow Cytometry, Human)	Flow Cytometry	Human
De-Kuan Chang, Jianhua Sui, Shusheng Geng, Asli Muvaffak, Mei Bai, Robert C. Fuhlbrigge et al. Humanization of an Anti-CCR4 Antibody That Kills Cutaneous T-Cell Lymphoma Cells and Abrogates Suppression by T-Regulatory Cells Molecular Cancer Therapeutics 11/1/2012 [PMID: 22869555]
Takashi Maehara, Masafumi Moriyama, Hitoshi Nakashima, Katsuhisa Miyake, Jun-Nosuke Hayashida, Akihiko Tanaka et al. Interleukin-21 contributes to germinal centre formation and immunoglobulin G4 production in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease Annals of the Rheumatic Diseases 12/1/2012 [PMID: 22753386]
Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA Identification of human NK17/NK1 cells. PLoS ONE, 2011-10-21;6(10):e26780. 2011-10-21 [PMID: 22039549] (Flow Cytometry, Human)	Flow Cytometry	Human
Islam SA, Chang DS, Colvin RA Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat. Immunol., 2011-01-09;12(2):167-77. 2011-01-09 [PMID: 21217759] (Flow Cytometry, Human)	Flow Cytometry	Human
Fifadara NH, Aye CC, Raghuwanshi SK, Richardson RM, Ono SJ CCR1 expression and signal transduction by murine BMMC results in secretion of TNF-alpha, TGFbeta-1 and IL-6. Int. Immunol., 2009-07-10;21(8):991-1001. 2009-07-10 [PMID: 19592420] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Nakamura M, Jo J, Tabata Y, Ishikawa O Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model. Am. J. Pathol., 2008-02-02;172(3):650-8. 2008-02-02 [PMID: 18245811] (IHC, Human)	IHC	Human
Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J. Immunol., 2007-09-15;179(6):3724-33. 2007-09-15 [PMID: 17785809] (Flow Cytometry, Human)	Flow Cytometry	Human
Ponte AL, Marais E, Gallay N, Langonne A, Delorme B, Herault O, Charbord P, Domenech J The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells, 2007-03-29;25(7):1737-45. 2007-03-29 [PMID: 17395768] (Flow Cytometry, Human)	Flow Cytometry	Human
Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, Boumsell L, D Buckley C, Buhring HJ, Clark G, Engel P, Fox D, Jin BQ, Macardle PJ, Malavasi F, Mason D, Stockinger H, Yang X CD molecules 2006--human cell differentiation molecules. J. Immunol. Methods, 2006-12-04;319(1):1-5. 2006-12-04 [PMID: 17174972] (Flow Cytometry, Human)	Flow Cytometry	Human
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin. Immunol., 2006-06-16;120(2):220-31. 2006-06-16 [PMID: 16782408] (Neutralization, Human)	Neutralization	Human
Marchal-Somme J, Uzunhan Y, Marchand-Adam S, Valeyre D, Soumelis V, Crestani B, Soler P Cutting edge: nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis. J. Immunol., 2006-05-15;176(10):5735-9. 2006-05-15 [PMID: 16670278] (IHC-Fr, Human)	IHC-Fr	Human
Ohshima K, Karube K, Kawano R, Tsuchiya T, Suefuji H, Yamaguchi T, Suzumiya J, Kikuchii M Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis. Int. J. Oncol., 2004-09-01;25(3):605-13. 2004-09-01 [PMID: 15289861] (ICC, Human)	ICC	Human
Nakayama EE, Tanaka Y, Nagai Y, Iwamoto A, Shioda T A CCR2-V64I polymorphism affects stability of CCR2A isoform. AIDS, 2004-03-26;18(5):729-38. 2004-03-26 [PMID: 15075507] (Flow Cytometry, Human)	Flow Cytometry	Human
Show All 27 Publications. Collapse Publications.

Gene Symbol	CCR4
Uniprot	P51679()