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CCR4 Antibody (205410) [Fluorescein]

 (14 Publications)
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Human peripheral blood lymphocytes were stained with Mouse Anti-Human/Rat CCR4 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB1567F) and Mouse Anti-Human CD3e APC-conjugated Monoclonal Antibody (Catalog # FAB100A). Quadrant markers were set based on control antibody staining (Catalog # IC0041F). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human/Rat CCR4 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB1567F) and Mouse Anti-Human CD3e APC-conjugated Monoclonal Antibody (Catalog # ...read more

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications Flow
Clone
205410
Clonality
Monoclonal
Host
Mouse
Conjugate
Fluorescein

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1567U-100UG
Alexa Fluor 405
FAB1567V-100UG
Alexa Fluor 488
FAB1567G-025
Alexa Fluor 532
FAB1567X
Alexa Fluor 594
FAB1567T-100UG
Alexa Fluor 647
FAB1567R-100
Alexa Fluor 647
FAB1567R-025
Alexa Fluor 700
FAB1567N-100UG
Alexa Fluor 750
FAB1567S-100UG
Allophycocyanin
FAB1567A-025
Allophycocyanin
FAB1567A-100
Allophycocyanin/Cy7
FAB1567APCCY7
Biotin
FAB1567B
DyLight 350
FAB1567D
DyLight 405
FAB1567E
DyLight 488
FAB1567K
DyLight 550
FAB1567L
DyLight 594
FAB1567M
DyLight 650
FAB1567W
DyLight 680
FAB1567Y
DyLight 755
FAB1567Z
Fluorescein
FAB1567F-100
HRP
FAB1567H
Janelia Fluor 549
FAB1567I
Janelia Fluor 646
FAB1567J
PE/Atto594
FAB1567PEATT594
PE/Cy5.5
FAB1567PECY55
PE/Cy7
FAB1567PECY7
PerCP (Peridinin-chlorophyll Protein Complex)
FAB1567C-100
PerCP (Peridinin-chlorophyll Protein Complex)
FAB1567C-025
Phycoerythrin
FAB1567P-100
Phycoerythrin
FAB1567P-025
Unconjugated
MAB1567-100
mFluor Violet 450 SE
FAB1567MFV450
mFluor Violet 500 SE
FAB1567MFV500
mFluor Violet 610 SE
FAB1567MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1567-100
Carrier Free
FAB1567G-025
Carrier Free
FAB1567S-100UG
Carrier Free
FAB1567T-100UG
Carrier Free
FAB1567U-100UG
Carrier Free
FAB1567V-100UG
Carrier Free
FAB1567R-100
Carrier Free
MAB1567-500
Carrier Free
MAB1567-100
Carrier Free
FAB1567R-025
Carrier Free
FAB1567C-025
Carrier Free
MAB1567-SP
Carrier Free
FAB1567A-100
Carrier Free
FAB1567A-025
Carrier Free
FAB1567P-100
Carrier Free
FAB1567P-025
Carrier Free
FAB1567F-100
Carrier Free
FAB1567C-100
Carrier Free
FAB1567N-100UG
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CCR4 Antibody (205410) [Fluorescein] Summary

Additional Information
Clone 205410 was used by HLDA to establish CD designation
Immunogen
Human CCR4 transfectants
Met1-Leu360
Accession # P51679
Specificity
Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects human CCR4 on human PBLs and platelets and rat CCR4 on rat splenocytes.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CCR4
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB1567F in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR4 Antibody (205410) [Fluorescein]

  • C-C chemokine receptor type 4
  • C-C CKR-4
  • CC-CKR-4HGCN:14099
  • CCR4
  • CCR-4
  • CD194 antigen
  • CD194
  • chemokine (C-C motif) receptor 4
  • chemokine (C-C) receptor 4
  • ChemR13
  • CKR4MGC88293
  • CMKBR4k5-5
  • K5-5

Background

CCR4 is a G protein-linked seven transmembrane domain chemokine receptor that binds the chemokines CCL17/TARC and CCL22/MDC. Current evidence suggests that CCR4 expression is associated with Th-2 type T cells and with platelets. CCR4 expression has also been reported in mature dendritic cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCR4 Antibody (FAB1567F)(14)

We have publications tested in 2 confirmed species: Human, Porcine.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(12)
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Human
(11)
Porcine
(1)
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Showing Publications 1 - 10 of 14. Show All 14 Publications.
Publications using FAB1567F Applications Species
Wang, Z;Ma, J;Zhang, H;Ramakrishna, R;Mintzlaff, D;Mathes, DW;Pomfret, EA;Lucia, MS;Gao, D;Haverkos, BM;Wang, Z; CCR4-IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T-cell lymphoma in a mouse CTCL model FEBS open bio 2023-05-08 [PMID: 37157185] (Flow Cytometry, Human) Flow Cytometry Human
L Amniai, C Ple, M Barrier, P de Nadai, P Marquillie, H Vorng, C Chenivesse, A Tsicopoulo, C Duez Natural Killer Cells from Allergic Donors Are Defective in Their Response to CCL18 Chemokine International Journal of Molecular Sciences, 2021-04-09;22(8):. 2021-04-09 [PMID: 33918621] (Flow Cytometry, Human) Flow Cytometry Human
Haoyu Wang, Zhaohui Wang, Huiping Zhang, Zeng Qi, Ariel C. Johnson, David Mathes et al. Bispecific human IL2‐CCR4 immunotoxin targets human cutaneous T‐cell lymphoma Molecular Oncology 5/1/2020 [PMID: 32107846]
A Kitadate, S Ikeda, F Abe, N Takahashi, N Shimizu, K Matsue, H Tagawa Histone deacetylase inhibitors downregulate CCR4 expression and decrease mogamulizumab efficacy in CCR4-positive mature T-cell lymphomas Haematologica, 2017-10-12;0(0):. 2017-10-12 [PMID: 29025909] (Flow Cytometry, Human) Flow Cytometry Human
Zhirui Wang Porcine Treg depletion with a novel diphtheria toxin-based anti-human CCR4 immunotoxin Vet. Immunol. Immunopathol., 2016-10-29;182(0):150-158. 2016-10-29 [PMID: 27863545] (Flow Cytometry, Porcine) Flow Cytometry Porcine
Zaidoon Al-Jaderi Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity Front Immunol, 2016-10-19;7(0):437. 2016-10-19 [PMID: 27807435] (Flow Cytometry, Human) Flow Cytometry Human
James E, Gates T, LaFond R, Yamamoto S, Ni C, Mai D, Gersuk V, O'Brien K, Nguyen Q, Zeitner B, Lanteri M, Norris P, Chaussabel D, Malhotra U, Kwok W Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome. PLoS Pathog, 2016-01-21;12(1):e1005375. 2016-01-21 [PMID: 26795118] (Flow Cytometry, Human) Flow Cytometry Human
Zhaohui Wang, Shannon G. Pratts, Huiping Zhang, Philip J. Spencer, Ruichao Yu, Makoto Tonsho et al. Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin Molecular Oncology 4/1/2016 [PMID: 26643572]
Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA Identification of human NK17/NK1 cells. PLoS ONE, 2011-10-21;6(10):e26780. 2011-10-21 [PMID: 22039549] (Flow Cytometry, Human) Flow Cytometry Human
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J. Immunol., 2010-02-17;184(6):2886-98. 2010-02-17 [PMID: 20164417] (Flow Cytometry, Human) Flow Cytometry Human
Show All 14 Publications.

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Bioinformatics

Gene Symbol CCR4
Uniprot