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CC Chemokine Receptor D6 Antibody (196124) [Unconjugated]

 (5 Publications)
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NS0 mouse myeloma cell line transfected with human CC Chemokine Receptor D6 was stained with Rat Anti-Human CC Chemokine Receptor D6 Monoclonal Antibody (Catalog # MAB1364, filled histogram) or isotype control antibody (Catalog # MAB006, open histogram), followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). View our protocol for Staining Membrane-associated Proteins.
NS0 mouse myeloma cell line transfected with human CC Chemokine Receptor D6 was stained with Rat Anti-Human CC Chemokine Receptor D6 Monoclonal Antibody (Catalog # MAB1364, filled histogram) or isotype control antibody ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
196124
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1364U-100UG
Alexa Fluor 405
FAB1364V-100UG
Alexa Fluor 488
FAB1364G-100UG
Alexa Fluor 532
FAB1364X
Alexa Fluor 594
FAB1364T-100UG
Alexa Fluor 647
FAB1364R-100UG
Alexa Fluor 700
FAB1364N-100UG
Alexa Fluor 750
FAB1364S-100UG
Allophycocyanin/Cy7
FAB1364APCCY7
Biotin
FAB1364B
DyLight 350
FAB1364D
DyLight 405
FAB1364E
DyLight 488
FAB1364K
DyLight 550
FAB1364L
DyLight 594
FAB1364M
DyLight 650
FAB1364W
DyLight 680
FAB1364Y
DyLight 755
FAB1364Z
HRP
FAB1364H
Janelia Fluor 525
FAB1364JF525
Janelia Fluor 549
FAB1364I
Janelia Fluor 646
FAB1364J
Janelia Fluor 669
FAB1364JF669
PE/Atto594
FAB1364PEATT594
PE/Cy5.5
FAB1364PECY55
PE/Cy7
FAB1364PECY7
PerCP
FAB1364C
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB1364-SP
Carrier Free
FAB1364V-100UG
Carrier Free
FAB1364U-100UG
Carrier Free
FAB1364T-100UG
Carrier Free
FAB1364S-100UG
Carrier Free
FAB1364R-100UG
Carrier Free
FAB1364N-100UG
Carrier Free
FAB1364G-100UG
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CC Chemokine Receptor D6 Antibody (196124) [Unconjugated] Summary

Immunogen
RBL-1 rat basophilic leukemia cell line transfected with human CC Chemokine Receptor D6
Met1-Ala384
Accession # O00590
Specificity
Detects human CC Chemokine Receptor D6 in transfectants. Does not stain the parent cell line.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CCBP2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
Publications
Read Publications using
MAB1364 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CC Chemokine Receptor D6 Antibody (196124) [Unconjugated]

  • ACKR2
  • C-C chemokine receptor D6
  • CCBP2
  • CCR10CCR9D6CC-chemokine-binding receptor JAB61
  • chemokine (C-C) receptor 9
  • chemokine binding protein 2
  • Chemokine receptor CCR-10
  • Chemokine receptor CCR-9
  • chemokine receptor D6
  • chemokine-binding protein 2
  • Chemokine-binding protein D6
  • CMKBR9
  • CMKBR9chemokine (C-C motif) receptor 9
  • D6
  • hD6
  • MGC126678
  • MGC138250

Background

D6 is a seven transmembrane receptor that appears to bind to most beta chemokines. D6 expression has been reported on endothelial cells lining afferent lymphatics, placenta and a number of primitive erythromyeloid cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CC Chemokine
Receptor D6 Antibody ...
MAB1364
CC Chemokine Receptor D6 Antibody (196124) [Unconjugated]
Species: Hu
Applications: Flow, CyTOF-ready

Publications for CC Chemokine Receptor D6 Antibody (MAB1364)(5)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: Flow Cytometry, ICC, IHC-Fr.


Filter By Application
Flow Cytometry
(4)
ICC
(3)
IHC-Fr
(1)
All Applications
Filter By Species
Human
(5)
All Species
Showing Publications 1 - 5 of 5.
Publications using MAB1364 Applications Species
C Tersigni, G Maulucci, R Castellani, G Bianchetti, M Onori, R Franco, G Barbaro, M De Spirito, A Lanzone, G Scambia, N Di Simone Enoxaparin Increases D6 Receptor Expression and Restores Cytoskeleton Organization in Trophoblast Cells from Preeclampsia Cells, 2022-06-27;11(13):. 2022-06-27 [PMID: 35805120] (ICC, Human) ICC Human
Hewit , Kay D, Fraser , Alasdair, Nibbs , Robert J, Graham , Gerard J The N-terminal region of the atypical chemokine receptor ACKR2 is a key determinant of ligand binding. J Biol Chem, 2014-03-18;289(18):12330-42. 2014-03-18 [PMID: 24644289] (Flow Cytometry, Human) Flow Cytometry Human
Savino B, Borroni EM, Torres NM, Proost P, Struyf S, Mortier A, Mantovani A, Locati M, Bonecchi R Recognition versus adaptive up-regulation and degradation of CC chemokines by the chemokine decoy receptor D6 are determined by their N-terminal sequence. J. Biol. Chem., 2009-07-24;284(38):26207-15. 2009-07-24 [PMID: 19632987] (Flow Cytometry, ICC, Human) Flow Cytometry, ICC Human
Bonecchi R, Borroni EM, Anselmo A, Doni A, Savino B, Mirolo M, Fabbri M, Jala VR, Haribabu B, Mantovani A, Locati M Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation. Blood, 2008-05-14;112(3):493-503. 2008-05-14 [PMID: 18480427] (Flow Cytometry, Human) Flow Cytometry Human
Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Proc. Natl. Acad. Sci. U.S.A., 2007-02-05;104(7):2319-24. 2007-02-05 [PMID: 17283337] (Flow Cytometry, ICC, IHC-Fr, Human) Flow Cytometry, ICC, IHC-Fr Human

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Bioinformatics

Gene Symbol CCBP2
Uniprot