CCR8 Antibody (191704) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CCR8 (C-C chemokine receptor 8; previously called CKR-L1 or TER1 and designated CD198) is a 41-43 kDa member of the GPCR 1 family of transmembrane proteins.  CCR8 is expressed on vascular smooth muscle cells, monocytes, eosinophils, peritoneal macrophages, thymocytes, CD8+ T cells, Langerhans cells and neurons.  CCL1/TCA3 and vMIP-1 are known agonists for CCR8.  Human CCR8 is a 7-transmembrane protein that is 355 amino acids (aa) in length.  It contains a 35 aa N-terminal extracellular domain plus a 51 aa C-terminal cytoplasmic tail. Over aa sequences 1-33 and 92-105 collectively, human and mouse CCR8 share 64% aa sequence identity.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Primate - Macaca mulatta (Rhesus Macaque).

We have publications tested in 1 application: Flow Cytometry.

Showing Publications 1 - 3 of 3.

Publications using MAB1429	Applications	Species
Minang JT, Trivett MT, Bolton DL, Trubey CM, Estes JD, Li Y, Smedley J, Pung R, Rosati M, Jalah R, Pavlakis GN, Felber BK, Piatak M, Roederer M, Lifson JD, Ott DE, Ohlen C Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones in rhesus macaques during acute infection. J. Immunol., 2009-11-30;184(1):315-26. 2009-11-30 [PMID: 19949091] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M, O'Connor D, Lifson JD, Roederer M, Ohlen C Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques. J. Immunol., 2009-11-30;184(1):303-14. 2009-11-30 [PMID: 19949089] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Hirahara K, Liu L, Clark RA, Yamanaka K, Fuhlbrigge RC, Kupper TS The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J. Immunol., 2006-10-01;177(7):4488-94. 2006-10-01 [PMID: 16982885] (Flow Cytometry, Human)	Flow Cytometry	Human

Array MAB1429

• CCR8 Antibodies
• CCR8 ELISA Kits