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CCR8 Antibody (191704) [PerCP (Peridinin-chlorophyll Protein Complex)]

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Human peripheral blood monocytes were stained with Rat Anti-Human/Rat CCR8 PerCP-conjugated Monoclonal Antibody (Catalog # FAB1429C, filled histogram) or isotype control antibody (Catalog # IC013C, open histogram). View ...read more
Rat peripheral blood cells were stained with Rat Anti-Human/Rat CCR8 PerCP-conjugated Monoclonal Antibody (Catalog # FAB1429C, filled histogram) or isotype control antibody (Catalog # IC013C, open histogram). View our ...read more

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications Flow
Clone
191704
Clonality
Monoclonal
Host
Rat
Conjugate
PerCP (Peridinin-chlorophyll Protein Complex)

Order Details

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CCR8 Antibody (191704) [PerCP (Peridinin-chlorophyll Protein Complex)] Summary

Additional Information
Clone 191704 was used by HLDA to establish CD designation
Immunogen
BaF3 mouse pro-B cell line transfected with human CCR8
Met1-Leu355
Accession # P51685
Specificity
Detects human CCR8. Neutralizes the bioactivity of human CCR8 and specifically stains human CCR8-transfected cell lines but not the parent cell lines.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
CCR8
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR8 Antibody (191704) [PerCP (Peridinin-chlorophyll Protein Complex)]

  • CC chemokine receptor 8
  • C-C CKR-8
  • CC-chemokine receptor chemr1
  • CC-CKR-8
  • CCR8
  • CCR-8
  • CD198
  • CDw198 antigen
  • CDw198
  • chemokine (C-C motif) receptor 8
  • chemokine (C-C) receptor 8
  • chemokine (C-C) receptor-like 2
  • Chemokine receptor-like 1
  • ChemR1
  • CKRL1
  • CKR-L1
  • CKRL1MGC129966
  • CMKBR8MGC129973
  • CMKBRL2C-C chemokine receptor type 8
  • CY6
  • GPRCL1
  • GPRCY6
  • GPR-CY6
  • TER-1
  • TER1CC chemokine receptor CHEMR1

Background

CCR8 (C-C chemokine receptor 8; previously called CKR-L1 or TER1 and designated CD198) is a 41-43 kDa member of the GPCR 1 family of transmembrane proteins.  CCR8 is expressed on vascular smooth muscle cells, monocytes, eosinophils, peritoneal macrophages, thymocytes, CD8+ T cells, Langerhans cells and neurons.  CCL1/TCA3 and vMIP-1 are known agonists for CCR8.  Human CCR8 is a 7-transmembrane protein that is 355 amino acids (aa) in length.  It contains a 35 aa N-terminal extracellular domain plus a 51 aa C-terminal cytoplasmic tail. Over aa sequences 1-33 and 92-105 collectively, human and mouse CCR8 share 64% aa sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CCR8
Uniprot