Name: CXCR6 Antibody (56811) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB699
Price: 459 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	Flow, CyTOF-ready
Clone	56811
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 FAB699U-100UG

Alexa Fluor 405 FAB699V-100UG

Alexa Fluor 488 FAB699G-100UG

Alexa Fluor 532 FAB699X

Alexa Fluor 594 FAB699T-100UG

Alexa Fluor 647 FAB699R-100UG

Alexa Fluor 700 FAB699N-100UG

Alexa Fluor 750 FAB699S-100UG

Allophycocyanin FAB699A-025

Allophycocyanin FAB699A-100

Allophycocyanin/Cy7 FAB699APCCY7

Biotin FAB699B

CoraFluor 1 FAB699CL1

DyLight 350 FAB699D

DyLight 405 FAB699E

DyLight 488 FAB699K

DyLight 550 FAB699L

DyLight 594 FAB699M

DyLight 650 FAB699W

DyLight 680 FAB699Y

DyLight 755 FAB699Z

FITC FAB699F

HRP FAB699H

Janelia Fluor 525 FAB699JF525

Janelia Fluor 549 FAB699I

Janelia Fluor 585 FAB699JF585

Janelia Fluor 635 FAB699JF635

Janelia Fluor 646 FAB699J

Janelia Fluor 669 FAB699JF669

PE/Atto594 FAB699PEATT594

PE/Cy5.5 FAB699PECY55

PE/Cy7 FAB699PECY7

Phycoerythrin FAB699P-100

Phycoerythrin FAB699P-025

mFluor Violet 450 SE FAB699MFV450

mFluor Violet 500 SE FAB699MFV500

mFluor Violet 610 SE FAB699MFV610

Catalog# & Formulation	Size	Price
Carrier Free FAB699P-025

Carrier Free FAB699P-100

Carrier Free FAB699A-025

Carrier Free FAB699A-100

Carrier Free MAB699-SP

Carrier Free FAB699V-100UG

Carrier Free FAB699U-100UG

Carrier Free FAB699T-100UG

Carrier Free FAB699S-100UG

Carrier Free FAB699R-100UG

Carrier Free FAB699N-100UG

Carrier Free FAB699G-100UG

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB699U-100UG
Alexa Fluor 405	FAB699V-100UG
Alexa Fluor 488	FAB699G-100UG
Alexa Fluor 532	FAB699X
Alexa Fluor 594	FAB699T-100UG
Alexa Fluor 647	FAB699R-100UG
Alexa Fluor 700	FAB699N-100UG
Alexa Fluor 750	FAB699S-100UG
Allophycocyanin	FAB699A-100
Allophycocyanin	FAB699A-025
Allophycocyanin/Cy7	FAB699APCCY7
Biotin	FAB699B
CoraFluor 1	FAB699CL1
DyLight 350	FAB699D
DyLight 405	FAB699E
DyLight 488	FAB699K
DyLight 550	FAB699L
DyLight 594	FAB699M
DyLight 650	FAB699W
DyLight 680	FAB699Y
DyLight 755	FAB699Z
FITC	FAB699F
HRP	FAB699H
Janelia Fluor 525	FAB699JF525
Janelia Fluor 549	FAB699I
Janelia Fluor 585	FAB699JF585
Janelia Fluor 635	FAB699JF635
Janelia Fluor 646	FAB699J
Janelia Fluor 669	FAB699JF669
PE/Atto594	FAB699PEATT594
PE/Cy5.5	FAB699PECY55
PE/Cy7	FAB699PECY7
Phycoerythrin	FAB699P-100
Phycoerythrin	FAB699P-025
mFluor Violet 450 SE	FAB699MFV450
mFluor Violet 500 SE	FAB699MFV500
mFluor Violet 610 SE	FAB699MFV610

CXCR6 Antibody (56811) [Unconjugated]

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CXCR6 Antibody (56811) [Unconjugated] Summary

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Alternate Names for CXCR6 Antibody (56811) [Unconjugated]

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Publications for CXCR6 Antibody (MAB699)(26)

Reviews for CXCR6 Antibody (MAB699) (0)

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Bioinformatics

Additional Information	Clone 56811 was used by HLDA to establish CD designation
Immunogen	NS0 mouse myeloma cell line transfected with human CXCR6 Met1-Leu342 Accession # O00574
Specificity	Stains human CXCR6 transfectants but not irrelevant transfectants.
Source	N/A
Isotype	IgG2b
Clonality	Monoclonal
Host	Mouse
Gene	CXCR6
Purity Statement	Protein A or G purified from ascites
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Publications using MAB699	Applications	Species
Wang, J;Chai, Q;Lei, Z;Wang, Y;He, J;Ge, P;Lu, Z;Qiang, L;Zhao, D;Yu, S;Qiu, C;Zhong, Y;Li, BX;Zhang, L;Pang, Y;Gao, GF;Liu, CH; LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis EMBO molecular medicine 2024-07-19 [PMID: 39030302] (CyTOF-reported, Human)	CyTOF-reported	Human
MC Lionetti, F Cola, O Chepizhko, MR Fumagalli, F Font-Clos, R Ravasio, S Minucci, P Canzano, M Camera, G Tiana, S Zapperi, CAM Porta MicroRNA-222 Regulates Melanoma Plasticity J Clin Med, 2020-08-08;9(8):. 2020-08-08 [PMID: 32784455] (Flow Cytometry, Human)	Flow Cytometry	Human
F Facciotti, P Larghi, R Bosotti, C Vasco, N Gagliani, C Cordiglier, S Mazzara, V Ranzani, E Rottoli, S Curti, A Penatti, B Karnani, Y Kobayashi, M Crosti, M Bombaci, JP van Hambur, G Rossetti, R Gualtierot, M Gerosa, S Gatti, S Torretta, L Pignataro, SW Tas, S Abrignani, M Pagani, F Grassi, PL Meroni, RA Flavell, J Geginat Evidence for a pathogenic role of extrafollicular, IL-10-producing CCR6+B helper T cells in systemic lupus erythematosus Proc. Natl. Acad. Sci. U.S.A., 2020-03-17;117(13):7305-7316. 2020-03-17 [PMID: 32184325] (Flow Cytometry, Human)	Flow Cytometry	Human
T Ikeda, M Nishita, K Hoshi, T Honda, Y Kakeji, Y Minami Mesenchymal stem cell-derived CXCL16 promotes progression of gastric cancer cells by STAT3-mediated expression of Ror1 Cancer Sci., 2020-02-25;111(4):1254-1265. 2020-02-25 [PMID: 32012403] (IHC, Human)	IHC	Human
Guan-Da Syu, Shih-Chin Wang, Guangzhong Ma, Shuang Liu, Donna Pearce, Atish Prakash et al. Development and application of a high-content virion display human GPCR array Nature Communications 2019-04-30 [PMID: 31040288]
V Adamski, R Mentlein, R Lucius, M Synowitz, J Held-Feind, K Hattermann The Chemokine Receptor CXCR6 Evokes Reverse Signaling via the Transmembrane Chemokine CXCL16 Int J Mol Sci, 2017-07-08;18(7):. 2017-07-08 [PMID: 28698473] (ICC, Human)	ICC	Human
S Pichyangku, MD Spring, K Yongvanitc, U Kum-Arb, A Limsalakpe, R Im-Erbsin, R Ubalee, P Vanachayan, EJ Remarque, E Angov, PL Smith, DL Saunders Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver PLoS ONE, 2017-02-09;12(2):e0171826. 2017-02-09 [PMID: 28182750] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque))	Flow Cytometry	Primate - Macaca mulatta (Rhesus Macaque)
Zaidoon Al-Jaderi Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity Front Immunol, 2016-10-19;7(0):437. 2016-10-19 [PMID: 27807435] (Flow Cytometry, Human)	Flow Cytometry	Human
Gosuke Takiguchi, Michiru Nishita, Kana Kurita, Yoshihiro Kakeji, Yasuhiro Minami Wnt5a-Ror2 signaling in mesenchymal stem cells promotes proliferation of gastric cancer cells by activating CXCL16-CXCR6 axis. Cancer Science, 2016-02-09;0(0):1349-7006. 2016-02-09 [PMID: 26708384] (Flow Cytometry, Human)	Flow Cytometry	Human
Hina Mir, Rajesh Singh, Goetz H. Kloecker, James W. Lillard, Shailesh Singh CXCR6 expression in non-small cell lung carcinoma supports metastatic process via modulating metalloproteinases Oncotarget 2015-04-30 [PMID: 25888629]
Hu , Weidong, Liu , Yue, Zhou , Wenhui, Si , Lianlian, Ren , Liang CXCL16 and CXCR6 are coexpressed in human lung cancer in vivo and mediate the invasion of lung cancer cell lines in vitro. PLoS ONE, 2014-06-04;9(6):e99056. 2014-06-04 [PMID: 24897301] (ICC, IHC-P, Human)	ICC, IHC-P	Human
Sun Jin Baek, Sung Keun Kang, Jeong Chan Ra In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors Experimental and Molecular Medicine 2011-10-31 [PMID: 21847008]
Jeffrey H. Ruth, Monica D. Arendt, M. Asif Amin, Salahuddin Ahmed, Hubert Marotte, Bradley J. Rabquer et al. Expression and function of CXCL16 in a novel model of gout Arthritis & Rheumatism 2010-06-03 [PMID: 20506383]
Pacheco-Rodriguez G, Kumaki F, Steagall WK, Zhang Y, Ikeda Y, Lin JP, Billings EM, Moss J Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. J. Immunol., 2009-02-01;182(3):1270-7. 2009-02-01 [PMID: 19155472] (IHC-P, Human)	IHC-P	Human
Gaida MM, Gunther F, Wagner C, Friess H, Giese NA, Schmidt J, Hansch GM, Wente MN Expression of the CXCR6 on polymorphonuclear neutrophils in pancreatic carcinoma and in acute, localized bacterial infections. Clin. Exp. Immunol., 2008-09-05;154(2):216-23. 2008-09-05 [PMID: 18778363] (Flow Cytometry, Human)	Flow Cytometry	Human
Wente MN, Gaida MM, Mayer C, Michalski CW, Haag N, Giese T, Felix K, Bergmann F, Giese NA, Friess H Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. Int. J. Oncol., 2008-08-01;33(2):297-308. 2008-08-01 [PMID: 18636150] (IHC-P, Human)	IHC-P	Human
Held-Feindt J, Rehmke B, Mentlein R, Hattermann K, Knerlich F, Hugo HH, Ludwig A, Mehdorn HM Overexpression of CXCL16 and its receptor CXCR6/Bonzo promotes growth of human schwannomas. Glia, 2008-05-01;56(7):764-74. 2008-05-01 [PMID: 18293410] (IHC, Western Blot, Human)	IHC, Western Blot	Human
Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J. Immunol., 2007-09-15;179(6):3724-33. 2007-09-15 [PMID: 17785809] (Flow Cytometry, Human)	Flow Cytometry	Human
Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis. J. Leukoc. Biol., 2007-07-05;82(4):946-55. 2007-07-05 [PMID: 17615381] (IHC-Fr, IHC-P, Human)	IHC-Fr, IHC-P	Human
Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, Boumsell L, D Buckley C, Buhring HJ, Clark G, Engel P, Fox D, Jin BQ, Macardle PJ, Malavasi F, Mason D, Stockinger H, Yang X CD molecules 2006--human cell differentiation molecules. J. Immunol. Methods, 2006-12-04;319(1):1-5. 2006-12-04 [PMID: 17174972] (Flow Cytometry, Human)	Flow Cytometry	Human
Hirahara K, Liu L, Clark RA, Yamanaka K, Fuhlbrigge RC, Kupper TS The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J. Immunol., 2006-10-01;177(7):4488-94. 2006-10-01 [PMID: 16982885] (Flow Cytometry, Human)	Flow Cytometry	Human
Patel DN, Bailey SR, Gresham JK, Schuchman DB, Shelhamer JH, Goldstein BJ, Foxwell BM, Stemerman MB, Maranchie JK, Valente AJ, Mummidi S, Chandrasekar B TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells. Biochem. Biophys. Res. Commun., 2006-07-13;347(4):1113-20. 2006-07-13 [PMID: 16870145] (Flow Cytometry, Human)	Flow Cytometry	Human
Ruth JH, Haas CS, Park CC, Amin MA, Martinez RJ, Haines GK, Shahrara S, Campbell PL, Koch AE CXCL16-mediated cell recruitment to rheumatoid arthritis synovial tissue and murine lymph nodes is dependent upon the MAPK pathway. Arthritis Rheum., 2006-03-01;54(3):765-78. 2006-03-01 [PMID: 16508941] (IHC, Human)	IHC	Human
Lim HW, Hillsamer P, Kim CH Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses. J. Clin. Invest., 2004-12-01;114(11):1640-9. 2004-12-01 [PMID: 15578096] (ICC, Human)	ICC	Human
Annels NE, Willemze AJ, van der Velden VH, Faaij CM, van Wering E, Sie-Go DM, Egeler RM, van Tol MJ, RÃƒÂ©vÃƒÂ©sz T Possible link between unique chemokine and homing receptor expression at diagnosis and relapse location in a patient with childhood T-ALL. Blood, 2003-12-04;103(7):2806-8. 2003-12-04 [PMID: 14656893] (Flow Cytometry, Human)	Flow Cytometry	Human
Campbell J, Qin S, Unutmaz D, Soler D, Murphy K, Hodge M, Wu L, Butcher E Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J Immunol, 2001-06-01;166(11):6477-82. 2001-06-01 [PMID: 11359797] (Flow Cytometry, Human)	Flow Cytometry	Human
Show All 26 Publications. Collapse Publications.

Gene Symbol	CXCR6
Uniprot	O00574()