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CCR2 Antibody (48607) [PE/Cy5.5]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
48607
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy5.5

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB150U-100UG
Alexa Fluor 405
FAB150V-100UG
Alexa Fluor 488
FAB151G-100
Alexa Fluor 488
FAB151G-025
Alexa Fluor 532
FAB150X
Alexa Fluor 594
FAB150T-100UG
Alexa Fluor 647
FAB150R-100UG
Alexa Fluor 700
FAB151N-100
Alexa Fluor 700
FAB151N-025
Alexa Fluor 750
FAB150S-100UG
Allophycocyanin
FAB151A-025
Allophycocyanin
FAB151A-100
Allophycocyanin/Cy7
FAB150APCCY7
Biotin
FAB151B
CoraFluor 1
FAB150CL1
DyLight 350
FAB150D
DyLight 405
FAB150E
DyLight 488
FAB150K
DyLight 550
FAB150L
DyLight 594
FAB150M
DyLight 650
FAB150W
DyLight 680
FAB150Y
DyLight 755
FAB150Z
FITC
FAB150F
HRP
FAB150H
Janelia Fluor 525
FAB150JF525
Janelia Fluor 549
FAB150I
Janelia Fluor 585
FAB150JF585
Janelia Fluor 635
FAB150JF635
Janelia Fluor 646
FAB150J
Janelia Fluor 669
FAB150JF669
PE/Atto594
FAB150PEATT594
PE/Cy7
FAB150PECY7
PerCP (Peridinin-chlorophyll Protein Complex)
FAB151C-100
PerCP (Peridinin-chlorophyll Protein Complex)
FAB151C-025
Phycoerythrin
FAB151P-025
Phycoerythrin
FAB151P-100
Unconjugated
MAB150-100
mFluor Violet 450 SE
FAB150MFV450
mFluor Violet 500 SE
FAB150MFV500
mFluor Violet 610 SE
FAB150MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB150-100
Carrier Free
FAB151G-100
Carrier Free
FAB150S-100UG
Carrier Free
FAB150T-100UG
Carrier Free
FAB150U-100UG
Carrier Free
FAB150V-100UG
Carrier Free
MAB150-SP
Carrier Free
FAB151N-100
Carrier Free
FAB151N-025
Carrier Free
FAB151G-025
Carrier Free
FAB151P-100
Carrier Free
FAB151B
Carrier Free
FAB151A-100
Carrier Free
FAB151A-025
Carrier Free
MAB150-100
Carrier Free
FAB151P-025
Carrier Free
FAB151C-100
Carrier Free
FAB151C-025
Carrier Free
FAB150R-100UG
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CCR2 Antibody (48607) [PE/Cy5.5] Summary

Additional Information
Clone 48607 was used by HLDA to establish CD designation
Immunogen
NS0 mouse myeloma cell line transfected with human CCR2
Met1-Leu360
Accession # NP_001116868
Specificity
Detects human CCR-2 transfectants but not the parental cell line or CCR-5 transfectants.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CCR2
Purity
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from ascites

Alternate Names for CCR2 Antibody (48607) [PE/Cy5.5]

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CC-CKR-2
  • CC-CKR-2CKR2B
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-R
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor

Background

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Isotype Controls

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Bioinformatics

Gene Symbol CCR2