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CCR2 Antibody (48607) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
48607
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB150U-100UG
Alexa Fluor 405
FAB150V-100UG
Alexa Fluor 488
FAB151G-025
Alexa Fluor 488
FAB150G
Alexa Fluor 488
FAB151G-100
Alexa Fluor 532
FAB150X
Alexa Fluor 594
FAB150T-100UG
Alexa Fluor 647
FAB150R-100UG
Alexa Fluor 700
FAB151N-100
Alexa Fluor 700
FAB151N-025
Alexa Fluor 700
FAB150N
Alexa Fluor 750
FAB150S-100UG
Allophycocyanin
FAB151A-025
Allophycocyanin
FAB151A-100
Allophycocyanin/Cy7
FAB150APCCY7
Biotin
FAB151B
DyLight 350
FAB150D
DyLight 405
FAB150E
DyLight 488
FAB150K
DyLight 550
FAB150L
DyLight 650
FAB150W
DyLight 680
FAB150Y
DyLight 755
FAB150Z
FITC
FAB150F
HRP
FAB150H
Janelia Fluor 549
FAB150I
Janelia Fluor 646
FAB150J
PE/Atto594
FAB150PEATT594
PE/Cy5.5
FAB150PECY55
PE/Cy7
FAB150PECY7
PerCP (Peridinin-chlorophyll Protein Complex)
FAB151C-100
PerCP (Peridinin-chlorophyll Protein Complex)
FAB151C-025
Phycoerythrin
FAB151P-100
Phycoerythrin
FAB151P-025
Unconjugated
MAB150-100
mFluor Violet 450 SE
FAB150MFV450
mFluor Violet 500 SE
FAB150MFV500
mFluor Violet 610 SE
FAB150MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB150-100
Carrier Free
FAB151G-100
Carrier Free
FAB150S-100UG
Carrier Free
FAB150T-100UG
Carrier Free
FAB150U-100UG
Carrier Free
FAB150V-100UG
Carrier Free
MAB150-SP
Carrier Free
FAB151N-100
Carrier Free
FAB151N-025
Carrier Free
FAB151G-025
Carrier Free
FAB151P-100
Carrier Free
FAB151B
Carrier Free
FAB151A-100
Carrier Free
FAB151A-025
Carrier Free
MAB150-100
Carrier Free
FAB151P-025
Carrier Free
FAB151C-100
Carrier Free
FAB151C-025
Carrier Free
FAB150R-100UG
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CCR2 Antibody (48607) [DyLight 594] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human CCR2
Met1-Leu360
Accession # NP_001116868
Specificity
Detects human CCR-2 transfectants but not the parental cell line or CCR-5 transfectants.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CCR2
Purity
Protein A or G purified from ascites
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from ascites

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CCR2 Antibody (48607) [DyLight 594]

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CC-CKR-2
  • CC-CKR-2CKR2B
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-R
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor

Background

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CCR2 Antibody
(48607) [DyLight 594]
FAB150M
CCR2 Antibody (48607) [DyLight 594]
Species: Hu
Applications: Flow, IHC, CyTOF-ready

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Isotype Controls

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Bioinformatics

Gene Symbol CCR2