CCR2 Antibody (475301) [Alexa Fluor® 700]

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CCR2, also known as CD192, is a 38 kDa 7TM chemokine receptor that preferentially binds CCL2, CCL7, and CCL13. CCR2 is expressed by multiple hematopoietic cells, endothelial cells, fibroblasts, neurons, and smooth muscle cells. It functions as an HIV fusion co-factor and facilitates T cell recruitment during inflammation. Two alternate splice forms (CCR2A and CCR2B) differ only by the addition of 14 amino acids to the intracellular carboxyl terminal. Mouse CCR2 shares 67% and 95% aa sequence identity with human and rat CCR2, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Transgenic Mouse.

We have publications tested in 2 applications: Flow Cytometry, IHC.

Showing Publications 1 - 10 of 12. Show All 12 Publications. Collapse Publications.

Publications using FAB5538N	Applications	Species
Anastasia du Halgouet, Aurélie Darbois, Mansour Alkobtawi, Martin Mestdagh, Aurélia Alphonse, Virginie Premel et al. Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing Immunity 1/10/2023 [PMID: 36630919]
A Lau, JJ Rahn, M Chappellaz, H Chung, H Benediktss, D Bihan, A von Mässen, A Linkermann, CN Jenne, SM Robbins, DL Senger, IA Lewis, J Chun, DA Muruve Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury Science Advances, 2022-02-02;8(5):eabm0142. 2022-02-02 [PMID: 35108057] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
K Tonecka, A Braniewska, Z Pilch, Z Sas, M Skorzynski, E Manuali, TP Rygiel The CD200 Regulates Inflammation in Mice Independently of TNF-&alpha Production International Journal of Molecular Sciences, 2021-05-19;22(10):. 2021-05-19 [PMID: 34069671] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
J Yu, MD Green, S Li, Y Sun, SN Journey, JE Choi, SM Rizvi, A Qin, JJ Waninger, X Lang, Z Chopra, I El Naqa, J Zhou, Y Bian, L Jiang, A Tezel, J Skvarce, RK Achar, M Sitto, BS Rosen, F Su, SP Narayanan, X Cao, S Wei, W Szeliga, L Vatan, C Mayo, MA Morgan, CA Schonewolf, K Cuneo, I Kryczek, VT Ma, CD Lao, TS Lawrence, N Ramnath, F Wen, AM Chinnaiyan, M Cieslik, A Alva, W Zou Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination Nature Medicine, 2021-01-04;0(0):. 2021-01-04 [PMID: 33398162] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
J Lian, AJ Ozga, CL Sokol, AD Luster Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization Cell Rep, 2020-05-26;31(8):107679. 2020-05-26 [PMID: 32460031] (IHC, Mouse)	IHC	Mouse
A Vasanthaku, D Chisanga, J Blume, R Gloury, K Britt, DC Henstridge, Y Zhan, SV Torres, S Liene, N Collins, E Cao, T Sidwell, C Li, RG Spallanzan, Y Liao, PA Beavis, T Gebhardt, N Trevaskis, SL Nutt, JD Zajac, RA Davey, MA Febbraio, D Mathis, W Shi, A Kallies Sex-specific adipose tissue imprinting of regulatory T cells Nature, 2020-02-26;0(0):. 2020-02-26 [PMID: 32103173] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
B Laffer, D Bauer, S Wasmuth, M Busch, TV Jalilvand, S Thanos, G Meyer Zu H, K Loser, T Langmann, A Heiligenha, M Kasper Loss of IL-10 Promotes Differentiation of Microglia to a M1 Phenotype Front Cell Neurosci, 2019-10-09;13(0):430. 2019-10-09 [PMID: 31649508] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
A Salvioni, M Belloy, A Lebourg, E Bassot, V Cantaloube, V Vasseur, S Blanié, RS Liblau, E Suberbiell, EA Robey, N Blanchard Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons Cell Rep, 2019-06-11;27(11):3254-3268.e8. 2019-06-11 [PMID: 31189109] (Flow Cytometry, Transgenic Mouse)	Flow Cytometry	Transgenic Mouse
C Miyabe, Y Miyabe, L Moreno, J Lian, RA Rahimi, NN Miura, N Ohno, Y Iwakura, T Kawakami, AD Luster Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis J. Clin. Invest., 2019-06-06;130(0):. 2019-06-06 [PMID: 31169521] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
A Hammami, BM Abidin, T Charpentie, A Fabié, AP Duguay, KM Heinonen, S Stäger HIF-1? is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis PLoS Pathog., 2017-09-11;13(9):e1006616. 2017-09-11 [PMID: 28892492] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
BM Abidin, A Hammami, S Stäger, KM Heinonen Infection-adapted emergency hematopoiesis promotes visceral leishmaniasis PLoS Pathog., 2017-08-07;13(8):e1006422. 2017-08-07 [PMID: 28787450] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Arango Duque G, Fukuda M, Turco S, Stager S, Descoteaux A Leishmania promastigotes induce cytokine secretion in macrophages through the degradation of synaptotagmin XI. J Immunol, 2014-07-25;193(5):2363-72. 2014-07-25 [PMID: 25063865] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Show All 12 Publications. Collapse Publications.

Array FAB5538N

• CCR2 Antibodies
• CCR2 ELISA Kit
• CCR2 Lysates
• CCR2 Proteins