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CCR2 Antibody (475301) [PE/Atto594]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
475301
Clonality
Monoclonal
Host
Rat
Conjugate
PE/Atto594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB5538U-100UG
Alexa Fluor 405
FAB5538V-100UG
Alexa Fluor 488
FAB5538G-100UG
Alexa Fluor 532
FAB55381X
Alexa Fluor 594
FAB5538T-100
Alexa Fluor 594
FAB5538T-025
Alexa Fluor 647
FAB5538R-025
Alexa Fluor 700
FAB5538N-025
Alexa Fluor 700
FAB5538N-100
Alexa Fluor 750
FAB5538S-025
Allophycocyanin
FAB5538A-025
Allophycocyanin
FAB5538A-100
Allophycocyanin/Cy7
FAB55381APCCY7
Biotin
FAB55381B
CoraFluor 1
FAB55381CL1
DyLight 350
FAB55381D
DyLight 405
FAB55381E
DyLight 488
FAB55381K
DyLight 550
FAB55381L
DyLight 594
FAB55381M
DyLight 650
FAB55381W
DyLight 680
FAB55381Y
DyLight 755
FAB55381Z
Fluorescein
FAB5538F-100
Fluorescein
FAB5538F-025
HRP
FAB55381H
Janelia Fluor 525
FAB55381JF525
Janelia Fluor 549
FAB55381I
Janelia Fluor 585
FAB55381JF585
Janelia Fluor 635
FAB55381JF635
Janelia Fluor 646
FAB55381J
Janelia Fluor 669
FAB55381JF669
PE/Cy5.5
FAB55381PECY55
PE/Cy7
FAB55381PECY7
PerCP
FAB55381C
Phycoerythrin
FAB5538P-025
Phycoerythrin
FAB5538P-100
Unconjugated
MAB55381-100
mFluor Violet 450 SE
FAB55381MFV450
mFluor Violet 500 SE
FAB55381MFV500
mFluor Violet 610 SE
FAB55381MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB55381-100
Carrier Free
FAB5538T-025
Carrier Free
FAB5538V-100UG
Carrier Free
FAB5538U-100UG
Carrier Free
MAB55381-SP
Carrier Free
MAB55381-100
Carrier Free
FAB5538T-100
Carrier Free
FAB5538R-025
Carrier Free
FAB5538S-025
Carrier Free
FAB5538F-025
Carrier Free
FAB5538N-100
Carrier Free
FAB5538N-025
Carrier Free
FAB5538A-100
Carrier Free
FAB5538A-025
Carrier Free
FAB5538P-100
Carrier Free
FAB5538P-025
Carrier Free
FAB5538F-100
Carrier Free
FAB5538G-100UG
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CCR2 Antibody (475301) [PE/Atto594] Summary

Immunogen
L1.2 mouse pro-B cell line transfected with mouse CCR2
Specificity
Detects mouse CCR2 transfectants but not the parental cell line in flow cytometry. Does not detect HEK293 human embryonic kidney cell line transfected with mouse CCR5 in flow cytometry.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for CCR2 Antibody (475301) [PE/Atto594]

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CC-CKR-2
  • CC-CKR-2CKR2B
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-R
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor

Background

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Isotype Controls

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