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TMC1 Antibody - BSA Free

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Western Blot: TMC1 Antibody [NBP3-05608] - Western blot analysis of extracts of mouse eye, using TMC1 antibody (NBP3-05608) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. ...read more
Immunohistochemistry-Paraffin: TMC1 Antibody [NBP3-05608] - Immunohistochemistry of paraffin-embedded human esophagus using TMC1 antibody (NBP3-05608) at dilution of 1:100 (40x lens).
Immunohistochemistry-Paraffin: TMC1 Antibody [NBP3-05608] - Immunohistochemistry of paraffin-embedded rat brain using TMC1 antibody (NBP3-05608) at dilution of 1:100 (40x lens).
Immunohistochemistry-Paraffin: TMC1 Antibody [NBP3-05608] - Immunohistochemistry of paraffin-embedded human prostate using TMC1 antibody (NBP3-05608) at dilution of 1:100 (40x lens).

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

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Catalog# & Formulation Size Price
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TMC1 Antibody - BSA Free Summary

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human TMC1 (NP_619636.2). INILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMC1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:2000
Theoretical MW
87 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS with 50% glycerol, pH7.3.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for TMC1 Antibody - BSA Free

  • DFNA36
  • DFNB11
  • DFNB7
  • transmembrane channel-like 1
  • transmembrane channel-like protein 1
  • Transmembrane cochlear-expressed protein 1
  • transmembrane, cochlear expressed, 1

Background

The TMC1 gene codes a 760 amino acid long, 87 kDA transmembrane channel-like protein 1 that is critical for the function of cochlear hair cells. The specific role of this gene, however, is unknown. This gene is known to interact with genes PRKAA1, MAP1LC3B, GABARAPL2, and NSMAF. Defects in the TMC1 gene cause deafness autosomal dominant type 36 and type 7. Additionally, it has been linked to nonsyndromic deafness, hearing loss, sensorineural hearing loss, megacolon, and enlarged vestibular aqueducts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional TMC1 Products

Array NBP3-05608

Research Areas for TMC1 Antibody (NBP3-05608)

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Blogs on TMC1

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Bioinformatics

Gene Symbol TMC1