Connexin 30/GJB6 Antibody (CL4540)

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Orthogonal Strategies: Immunocytochemistry/ Immunofluorescence: Connexin 30/GJB6 Antibody (CL4540) [NBP2-61141] - Staining of MCF7 cells using the Anti-GJB6 monoclonal antibody, showing no specific staining of ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clone
CL4540
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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Reviews & Publications
Protocols & FAQs
Support & Research

Connexin 30/GJB6 Antibody (CL4540) Summary

Immunogen
This antibody was developed against a synthetic peptide corresponding to the following amino acid sequence:RSKRAQTQKNHPNHALKESK
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GJB6
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 2-10 ug/ml
  • Immunohistochemistry Reactivity reported in (PMID: 31205407)
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Publications
Read Publication using
NBP2-61141 in the following applications:

Reactivity Notes

Mouse, Rat (85%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for Connexin 30/GJB6 Antibody (CL4540)

  • Connexin 30
  • connexin-30
  • CX30
  • CX30gap junction protein, beta 6
  • DFNA3B
  • DFNB1B
  • ectodermal dysplasia 2, hidrotic (Clouston syndrome)
  • ED2
  • EDH
  • gap junction beta-6 protein
  • gap junction protein, beta 6 (connexin 30)
  • gap junction protein, beta 6, 30kDa
  • GJB6
  • HEDDFNA3

Background

The connexin gene family codes for the protein subunits of gap junction channels that mediate direct diffusion of ions and metabolites between the cytoplasm of adjacent cells. Connexins span the plasma membrane 4 times, with amino- and carboxy-terminal regions facing the cytoplasm. Connexin genes are expressed in a cell type-specific manner with overlapping specificity. The gap junction channels have unique properties depending on the type of connexins constituting the channel.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GJB6