Connexin 30/GJB6 Antibody (CL4540) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clone
CL4540
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

Connexin 30/GJB6 Antibody (CL4540) [Janelia Fluor® 646] Summary

Immunogen
This antibody was developed against a synthetic peptide corresponding to the following amino acid sequence:RSKRAQTQKNHPNHALKESK
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GJB6
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse, Rat (85%).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Connexin 30/GJB6 Antibody (CL4540) [Janelia Fluor® 646]

  • Connexin 30
  • connexin-30
  • CX30
  • CX30gap junction protein, beta 6
  • DFNA3B
  • DFNB1B
  • ectodermal dysplasia 2, hidrotic (Clouston syndrome)
  • ED2
  • EDH
  • gap junction beta-6 protein
  • gap junction protein, beta 6 (connexin 30)
  • gap junction protein, beta 6, 30kDa
  • GJB6
  • HEDDFNA3

Background

The connexin gene family codes for the protein subunits of gap junction channels that mediate direct diffusion of ions and metabolites between the cytoplasm of adjacent cells. Connexins span the plasma membrane 4 times, with amino- and carboxy-terminal regions facing the cytoplasm. Connexin genes are expressed in a cell type-specific manner with overlapping specificity. The gap junction channels have unique properties depending on the type of connexins constituting the channel.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol GJB6