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TMC2 Antibody

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Immunohistochemistry-Paraffin: TMC2 Antibody [NBP1-92514] - Staining of human skin shows strong cytoplasmic positivity in keratinocytes.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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TMC2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: QVLREVEKSHKSVKGKATARDSEDTPKSSSKNATQLQLTKEETTPPSASQSQAMDKKAQGPGTSNSASRT
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMC2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
TMC2 Protein (NBP1-92514PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TMC2 Antibody

  • C20orf145
  • dJ686C3.3
  • transmembrane channel-like 2
  • transmembrane channel-like protein 2
  • Transmembrane cochlear-expressed protein 2
  • transmembrane, cochlear expressed, 2

Background

FUNCTION: May be required for the normal function of cochlear hair cells. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Inner ear and testis. DEVELOPMENTAL STAGE: Expressed at low, constant levels in temporal bone from embryonic day 14 to day 1 after birth. Increases by 8 to 16-fold at day 5, 10 and 20.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TMC2