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EVER2 Antibody - BSA Free

Images

 
Western Blot: EVER2 Antibody [NBP1-76903] - Jurkat cell lysate with EVER2 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: EVER2 Antibody [NBP1-76903] - Human Brain cells.
Immunohistochemistry-Paraffin: EVER2 Antibody [NBP1-76903] - Human brain with EVER2 antibody at 5 ug/ml.
Immunocytochemistry/ Immunofluorescence: EVER2 Antibody - BSA Free [NBP1-76903] - Immunofluorescence of EVER2 in Human Brain cells with EVER2 antibody at 20 u/mL.
Immunocytochemistry/ Immunofluorescence: EVER2 Antibody - BSA Free [NBP1-76903] - Immunofluorescence of EVER2 in Human Brain cells with EVER2 antibody at 20 u/mL.
Immunohistochemistry: EVER2 Antibody - BSA Free [NBP1-76903] - Immunohistochemistry of EVER2 in human brain with EVER2 antibody at 5 u/mL.
Immunohistochemistry: EVER2 Antibody - BSA Free [NBP1-76903] - Immunohistochemistry of EVER2 in human brain with EVER2 antibody at 5 u/mL.
Immunocytochemistry/ Immunofluorescence: EVER2 Antibody - BSA Free [NBP1-76903] - Immunofluorescence of EVER2 in Human Brain cells with EVER2 antibody at 20 u/mL.
Immunocytochemistry/ Immunofluorescence: EVER2 Antibody - BSA Free [NBP1-76903] - Immunofluorescence of EVER2 in Human Brain cells with EVER2 antibody at 20 u/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

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EVER2 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 14 amino acid synthetic peptide from near the center of human EVER2. The immunogen is located within amino acids 300 - 350 of EVER2. Amino Acid Squence: WATKYSQDNKEESL
Specificity
At least three isoforms of EVER2 are known to exist; this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMC8
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1-2 ug/ml
Control Peptide
EVER2 Peptide (NBP1-76903PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for EVER2 Antibody - BSA Free

  • epidermodysplasia verruciformis 2
  • Epidermodysplasia verruciformis protein 2
  • EV2
  • EVER2MGC102701
  • EVIN2FLJ43684
  • FLJ40668
  • MGC40121
  • transmembrane channel-like 8
  • transmembrane channel-like protein 8

Background

Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc. At least three isoforms of EVER2 are known to exist; this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol TMC8
Uniprot