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Myosin VIIa Antibody (SR1387)

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Western Blot: Myosin VIIa Antibody (SR1387) [NBP3-21878] - Western blot analysis using NBP3-21878 in Y79 cell lysate.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF
Clone
SR1387
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Myosin VIIa Antibody (SR1387) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Myosin VIIa (Uniprot #: Q13402)
Specificity
Detects endogenous levels of total Myosin VIIa
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
MYO7A
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:100
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Western Blot 1:500-1:2000
Theoretical MW
254 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Myosin VIIa Antibody (SR1387)

  • deafness, autosomal dominant 11
  • deafness, autosomal recessive 2
  • DFNA11
  • DFNB2
  • myosin VIIA
  • myosin-VIIa
  • MYOVIIA
  • MYU7A
  • USH1Bsevere))

Background

Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Myosin VIIa Antibody (NBP3-21878) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MYO7A