Human Total TrkB DuoSet IC ELISA, 2 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 3 of 3.

Publications using DYC397-2	Applications	Species
Li, H;Zhao, M;Jiang, C;Zhao, H;Wu, C;Li, Y;Zhang, S;Xu, P;Mou, T;Xu, Y;Huang, M; Elevated Plasma Levels of Mature Brain-Derived Neurotrophic Factor in Major Depressive Disorder Patients with Higher Suicidal Ideation Brain sciences 2023-08-21 [PMID: 37626579] (Human)		Human
C Wu, J Lu, S Lu, M Huang, Y Xu Increased ratio of mature BDNF to precursor-BDNF in patients with major depressive disorder with severe anhedonia J Psychiatr Res, 2020-05-12;126(0):92-97. 2020-05-12 [PMID: 32428748] (Human)		Human
H Jiang, S Chen, C Li, N Lu, Y Yue, Y Yin, Y Zhang, X Zhi, D Zhang, Y Yuan The serum protein levels of the tPA-BDNF pathway are implicated in depression and antidepressant treatment Transl Psychiatry, 2017-04-04;7(4):e1079. 2017-04-04 [PMID: 28375203] (Human)		Human

Array DYC397-2

• TrkB Antibodies
• TrkB Antibody Pair
• TrkB ELISA Kits
• TrkB Lysates
• TrkB Proteins
• TrkB Proteins and Enzymes
• TrkB ELISAs