Western Blot: tropomyosin-3 Antibody (2E4) [H00007170-M02] - Enrichment of tumor proteins in plasma-derived EVs and classifier performance. Immunoblot analysis of plasma-derived extracellular vesicles from ...read more
Immunohistochemistry-Paraffin: tropomyosin-3 Antibody (2E4) [H00007170-M02] - Analysis of monoclonal antibody to TPM3 on formalin-fixed paraffin-embedded human smooth muscle. Antibody concentration 3 ug/ml.
Sandwich ELISA: tropomyosin-3 Antibody (2E4) [H00007170-M02] - Detection limit for recombinant GST tagged TPM3 is 0.1 ng/ml as a capture antibody.
Western Blot: tropomyosin-3 Antibody (2E4) [H00007170-M02] - Enrichment of tumor proteins in plasma-derived EVs & classifier performance(A) Differential enrichment of EV proteins was evaluated for proteins with ≥ ...read more
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
TPM3 (AAH15403, 1 a.a. ~ 248 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKRLSAAEEKYSQKEDKYEGEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM
Specificity
TPM3 - tropomyosin 3 (2E4)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TPM3
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for tropomyosin-3 Antibody (2E4)
cytoskeletal tropomyosin TM30
FLJ41118
gamma-tropomyosin
heat-stable cytoskeletal protein 30 kDa
hscp30
hTM5
MGC14582
MGC3261
MGC72094
NEM1
OK/SW-cl.5
TM3
TM30
TM30nm
TM-5
TPMsk3
TRK
tropomyosin 3
tropomyosin alpha-3 chain
tropomyosin gamma
tropomyosin-3
tropomyosin-5
Background
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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