KHSRP Antibody

KH-type splicing regulatory protein (KSRP) contains four K homology RNA-binding domains. KH domains are found in a wide variety of proteins including ribosomal proteins, transcription factors, and mRNA processing proteins. KSRP has been found to promote the degradation of mRNAs that encode proteins involved in proliferation and the inflammatory response. Alternative names for KSRP include Far upstream element-binding protein 2, FUSE-binding protein 2, p75 and FUBP2.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 4 applications: ICC/IF, IHC-P, IP, WB.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using NBP1-18910	Applications	Species
Todorova V, Merolla L, Karademir D et al. Retinal Layer Separation (ReLayS) method enables the molecular analysis of photoreceptor segments and cell bodies, as well as the inner retina Scientific reports 2022-11-23 [PMID: 36424523] (WB, Mouse) Details: Dilutions: 1:5000	WB	Mouse
Singh S, Shaikh I, More S et al. Blockage of KHSRP-NLRP3 by MCC950 Can Reverse the Effect of Manganese-Induced Neuroinflammation in N2a Cells and Rat Brain International Journal of Molecular Sciences 2022-10-30 [PMID: 36362011] (WB, Mouse)	WB	Mouse
Olguin SL, Patel P, Buchanan CN et al. KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization Communications biology 2022-07-07 [PMID: 35798971] (IHC-P, Mouse)	IHC-P	Mouse
Patel P, Buchanan CN, Zdradzinski MD et al. Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs Nucleic acids research 2022-06-10 [PMID: 35556128] (ICC/IF, Mouse) Details: 1:200 ICC/IF dilution	ICC/IF	Mouse
Schmidtke L, Meineck M, Saurin S Et al. Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Faslpr Mice Cells 2021-11-14 [PMID: 34831390] (WB, Mouse)	WB	Mouse
Schmidtke L, Schrick K, Saurin S et al. The KH-type splicing regulatory protein (KSRP) regulates type III interferon expression post-transcriptionally Biochem. J. 2018-12-21 [PMID: 30578289] (IP, Human)	IP	Human
Agca C, Boldt K, Gubler A et al. Expression of leukemia inhibitory factor in Muller glia cells is regulated by a redox-dependent mRNA stability mechanism BMC Biol. 2015-04-25 [PMID: 25907681] (ICC/IF, Rat)	ICC/IF	Rat
Bird CW, Gardiner AS, Bolognani F et al. KSRP Modulation of GAP-43 mRNA Stability Restricts Axonal Outgrowth in Embryonic Hippocampal Neurons. PLoS One. 2013-11-14 [PMID: 24244461] (IP, Mouse)	IP	Mouse
Zhou R, Gong AY, Eischeid AN et al. miR-27b targets KSRP to coordinate TLR4-mediated epithelial defense against Cryptosporidium parvum infection. PLoS Pathog 2012-01-01 [PMID: 22615562]
Neff AT, Lee JY, Wilusz J et al. Global analysis reveals multiple pathways for unique regulation of mRNA decay in induced pluripotent stem cells. Genome Res 2012-07-06 [PMID: 22534399] (WB, Human)	WB	Human
Otsuka M, Takata A, Yoshikawa T et al. Receptor for Activated Protein Kinase C: Requirement for Efficient MicroRNA Function and Reduced Expression in Hepatocellular Carcinoma. PLoS One 2011-09-15 [PMID: 21935400]
Show All 11 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	IHC-Fr	Mouse	02/24/2014	View Summary Application Immunohistochemistry-Frozen Sample Tested mouse brain Species Mouse

Array NBP1-18910

• KHSRP Antibodies
• KHSRP Lysate
• KHSRP Proteins