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CXCR6 Antibody [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 450 SE

Order Details

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CXCR6 Antibody [mFluor Violet 450 SE] Summary

Immunogen
Antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bonzo/STRL33. The immunogen is located within the first 50 amino acids of Bonzo. Amino Acid Squence: GFSSFNDSSQEEHQD
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CXCR6
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CXCR6 Antibody [mFluor Violet 450 SE]

  • Bonzo
  • BONZOG-protein coupled receptor bonzo
  • CD186 antigen
  • CD186
  • CDw186
  • chemokine (C-X-C motif) receptor 6
  • C-X-C chemokine receptor type 6
  • CXCR6
  • CXC-R6
  • CXCR-6
  • G protein-coupled receptor
  • STRL33
  • STRL33G-protein coupled receptor STRL33
  • TYMSTRCD186

Background

Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use other chemokine receptors, such as CXCR6, a T-lymphocyte-expressed seven-transmembrane domain receptor that mediates fusion, entry, and trafficking of tumor-infiltrating lymphocytes. CXCR6 has been identified in human blood (T-lymphocytes, activated peripheral blood lymphocytes, monocyte-derived dendritic cells, primitive cord blood cells), placental trophoblasts, T-lymphocytes and dendritic cells in the skin, lymphoid tissues, and in fetal brain astrocytes. ESTs have been isolated from human normal placenta, liver/spleen, and pregnant uterus libraries, and human cancer kidney and uterus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CXCR6 Antibody (NBP1-76871MFV450) (0)

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Secondary Antibodies

 

Isotype Controls

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Blogs on CXCR6

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mFluor Violet Conjugated Antibodies

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol CXCR6