CXCR6 Antibody (879112) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CXCR6, also known as BONZO, STRL33, and CD186, is an approximately 45 kDa 7-TM domain chemokine receptor for the membrane-bound and soluble forms of CXCL16. CXCR6 is expressed on monocytes as well as on NKT, NK, CD4⁺, and CD8⁺ T cells. It is up-regulated in a variety of cancers. CXCR6 mediates the recruitment of immune cells to sites of inflammation and tissue damage. It also promotes NK cell memory and tolerance to NKT cell-mediated graft rejection. CXCR6 enhances the invasiveness of both tumor cells and glial precursor cells. In addition, it can function as a cellular receptor for select variants of HIV types 1 and 2. Rat CXCR6 shares 72% and 88% amino acid sequence identity with human and mouse CXCR6, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array MAB8196

• CXCR6 Antibodies
• CXCR6 ELISA Kits
• CXCR6 Protein