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BIN1 Antibody [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
HRP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-46170AF350
Alexa Fluor 405
NBP1-46170AF405
Alexa Fluor 488
NBP1-46170AF488
Alexa Fluor 532
NBP1-46170AF532
Alexa Fluor 594
NBP1-46170AF594
Alexa Fluor 647
NBP1-46170AF647
Alexa Fluor 700
NBP1-46170AF700
Alexa Fluor 750
NBP1-46170AF750
Allophycocyanin
NBP1-46170APC
Biotin
NBP1-46170B
CoraFluor 1
NBP1-46170CL1
DyLight 350
NBP1-46170UV
DyLight 405
NBP1-46170V
DyLight 488
NBP1-46170G
DyLight 550
NBP1-46170R
DyLight 594
NBP1-46170DL594
DyLight 650
NBP1-46170C
DyLight 680
NBP1-46170FR
DyLight 755
NBP1-46170IR
FITC
NBP1-46170F
Janelia Fluor 525
NBP1-46170JF525
Janelia Fluor 549
NBP1-46170JF549
Janelia Fluor 585
NBP1-46170JF585
Janelia Fluor 635
NBP1-46170JF635
Janelia Fluor 646
NBP1-46170JF646
Janelia Fluor 669
NBP1-46170JF669
PE
NBP1-46170PE
PerCP
NBP1-46170PCP
Unconjugated
NBP1-46170
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BIN1 Antibody [HRP] Summary

Immunogen
The immunogen for this product maps to a region between residue 543 and 593 of human Bridging Integrator 1 using the numbering given in entry NP_647593.1 (GeneID 274).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BIN1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for BIN1 Antibody [HRP]

  • AMPH2
  • Amphiphysin II
  • Amphiphysin-like protein
  • AMPHLDKFZp547F068
  • box dependant MYC interacting protein 1
  • bridging integrator 1Box-dependent myc-interacting protein 1
  • MGC10367
  • myc box-dependent-interacting protein 1
  • SH3P9

Background

BIN1 encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol BIN1