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TMC1 Antibody

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Western Blot: TMC1 Antibody [NBP3-11011] - Western blot analysis of TMC1 in Mouse MEF Whole Cell lysates. Antibody dilution at 1ug/ml

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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TMC1 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of mouse TMC1 (NP_083229.1). Peptide sequence RDVINEDDPEPEPEDEETRKAREKERRRRLRRGAEEEEEIDEEELERLKA
Clonality
Polyclonal
Host
Rabbit
Gene
TMC1
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
Theoretical MW
83 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for TMC1 Antibody

  • DFNA36
  • DFNB11
  • DFNB7
  • transmembrane channel-like 1
  • transmembrane channel-like protein 1
  • Transmembrane cochlear-expressed protein 1
  • transmembrane, cochlear expressed, 1

Background

The TMC1 gene codes a 760 amino acid long, 87 kDA transmembrane channel-like protein 1 that is critical for the function of cochlear hair cells. The specific role of this gene, however, is unknown. This gene is known to interact with genes PRKAA1, MAP1LC3B, GABARAPL2, and NSMAF. Defects in the TMC1 gene cause deafness autosomal dominant type 36 and type 7. Additionally, it has been linked to nonsyndromic deafness, hearing loss, sensorineural hearing loss, megacolon, and enlarged vestibular aqueducts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TMC1 Antibody (NBP3-11011) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for TMC1 Antibody (NBP3-11011) (0)

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Secondary Antibodies

 

Isotype Controls

Additional TMC1 Products

Array NBP3-11011

Research Areas for TMC1 Antibody (NBP3-11011)

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Blogs on TMC1

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Contact Information

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Bioinformatics

Gene Symbol TMC1