Synaptopodin Antibody - BSA Free

SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 4 applications: ELISA, ICC/IF, IHC-Fr, WB.

Showing Publications 1 - 10 of 10.

Publications using NBP2-39100	Applications	Species
Yan Li, Usman Muhammad, Ellen Sapp, Yuting Ke, Zejian Wang, Adel Boudi, Marian DiFiglia, Xueyi Li Chronic pharmacologic manipulation of dopamine transmission ameliorates metabolic disturbance in trappc9-linked brain developmental syndrome. JCI insight 2024-06-18 [PMID: 38889014]
Yang Q, Wang L, Liang Y et al. Loss of UCP2 causes mitochondrial fragmentation by OMA1-dependent proteolytic processing of OPA1 in podocytes FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023-11-01 [PMID: 37874273] (WB)	WB
Chen J. Fine granular deposition of clonal immunoreactivity on podocyte cell bodies: a primary podocytopathy marker and potential clue to disease mechanism. Thesis 1905-07-10 (ICC/IF, Human)	ICC/IF	Human
Wei M, Qiu Z, Li H et al. Integrating network pharmacology approach and experimental validation to reveal the alleviation of Shenkangning capsule on chronic nephritis Journal of Ethnopharmacology 2022-08-01 [PMID: 36057408] (ELISA, Mouse)	ELISA	Mouse
Tao Y, Chaudhari S, Shotorbani PY et al. Enhanced Orai1-mediated store-operated Ca2+ channel/calpain signaling contributes to high glucose-induced podocyte injury The Journal of biological chemistry 2022-04-28 [PMID: 35490782] (WB, Human)	WB	Human
Kulikov AA, Naumova AA, Aleksandrova EP Et al. Audiogenic kindling stimulates aberrant neurogenesis, synaptopodin expression, and mossy fiber sprouting in the hippocampus of rats genetically prone to audiogenic seizures Epilepsy & behavior : E&B 2021-12-01 [PMID: 34837844] (IHC-Fr, Rat)	IHC-Fr	Rat
Moon SJ, Jeong JY, Kim JH et al. The potential roles of NAD(P)H:quinone oxidoreductase 1 in the development of diabetic nephropathy and actin polymerization Sci Rep 2020-10-20 [PMID: 33082368] (ICC/IF, Mouse)	ICC/IF	Mouse
Yuan Q, Miao J, Yang Q et al. Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation Cell Death Dis 2020-05-11 [PMID: 32393782] (WB, Mouse)	WB	Mouse
Li H, Zhang W, Zhong F et al. Epigenetic regulation of RCAN1 expression in kidney disease and its role in podocyte injury. kidney Int. 2018-10-23 [PMID: 30366682] (ICC/IF, Human)	ICC/IF	Human
Chen W, Wu Y, Zhang G et al. GdT Cells Exacerbate Podocyte Injury via the CD28/B7-1-Phosphor-SRC Kinase Pathway Biomed Res Int. [PMID: 29862277] (ICC/IF, Mouse)	ICC/IF	Mouse

Array NBP2-39100

• Synaptopodin Antibodies
• Synaptopodin ELISA Kit
• Synaptopodin Proteins