Albumin Antibody (188835) [Unconjugated] - Serum

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Albumins are a family of globular proteins, the most common of which are serum albumins. Albumins are commonly found in blood plasma, and are unique from other blood proteins in that they are not glycosylated. Albumin is a 65-70 kDa protein with serum albumin being the main protein of human blood plasma. It binds water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates) - its main function is to regulate the colloidal osmotic pressure of blood. Albumin comprises three homologous domains that assemble to form a heart-shaped molecule. Each domain is a product of two subdomains that possess common structural motifs. The principal regions of ligand binding to human serum albumin are located in hydrophobic cavities in subdomains IIA and IIIA, which exhibit similar chemistry. Structurally, the serum albumins are similar, each domain containing five or six internal disulfide bonds.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 7 applications: ELISA Detection, Flow Cytometry, ICC, ICC/IF, IHC, IHC-Fr, Western Blot.

Showing Publications 1 - 10 of 54. Show All 54 Publications. Collapse Publications.

Publications using MAB1455	Applications	Species
Y Chen, L Chen, X Wu, Y Zhao, Y Wang, D Jiang, X Liu, T Zhou, S Li, Y Wei, Y Liu, C Hu, B Zhou, J Qin, H Ying, Q Ding Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice Nature Communications, 2023-03-18;14(1):1521. 3/18/2023 [PMID: 36934083]
Xiaoshan Wu, Dacheng Jiang, Yi Yang, Shuang Li, Qiurong Ding Modeling drug-induced liver injury and screening for anti-hepatofibrotic compounds using human PSC-derived organoids Cell Regeneration 3/3/2023 [PMID: 36864321]
S Ghafoory, C Stengl, S Kopany, M Mayadag, N Mechtel, B Murphy, S Schattschn, N Wilhelmi, S Wölfl Oxygen Gradient Induced in Microfluidic Chips Can Be Used as a Model for Liver Zonation Cells, 2022-11-23;11(23):. 2022-11-23 [PMID: 36496994] (ICC/IF, Human)	ICC/IF	Human
Rong Li, Yang Zhao, Jeffrey J. Yourick, Robert L. Sprando, Xiugong Gao Phenotypical, functional and transcriptomic comparison of two modified methods of hepatocyte differentiation from human induced pluripotent stem cells Biomedical Reports 3/23/2022 [PMID: 35371477]
Satoshi Muraoka, Masayo Hirano, Junko Isoyama, Satoshi Nagayama, Takeshi Tomonaga, Jun Adachi Comprehensive proteomic profiling of plasma and serum phosphatidylserine-positive extracellular vesicles reveals tissue-specific proteins iScience 4/15/2022 [PMID: 35340435]
MAS de Toledo, X Fu, F Kluge, K Götz, S Schmitz, P Wanek, HM Schüler, K Pannen, N Chatain, S Koschmiede, TH Brümmendor, M Zenke CRISPR/Cas9-engineered human ES cells harboring heterozygous and homozygous c-KIT knockout Stem Cell Research, 2022-03-01;60(0):102732. 2022-03-01 [PMID: 35279545] (ICC, Human)	ICC	Human
M Ramirez-Ga, V Berge, A Lin?, A Llorente Potential of miRNAs in urinary extracellular vesicles for management of active surveillance in prostate cancer patients British Journal of Cancer, 2021-11-22;0(0):. 2021-11-22 [PMID: 34811506] (Western Blot, Human)	Western Blot	Human
Alex P. Shephard, Peter Giles, Mariama Mbengue, Amr Alraies, Lisa K. Spary, Howard Kynaston et al. Stroma‐derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Journal of Extracellular Vesicles 10/1/2021 [PMID: 34596356]
Baoyan Xu, Qiao Yang, Yingzi Tang, Zhaoxia Tan, Haiyan Fu, Jing Peng et al. SIX1/EYA1 are novel liver damage biomarkers in chronic hepatitis B and other liver diseases Annals of Translational Medicine 6/1/2021 [PMID: 34277792]
Megan I. Mitchell, Iddo Z. Ben‐Dov, Christina Liu, Kenny Ye, Kar Chow, Yael Kramer et al. Extracellular Vesicle Capture by AnTibody of CHoice and Enzymatic Release (EV‐CATCHER): A customizable purification assay designed for small‐RNA biomarker identification and evaluation of circulating small‐EVs Journal of Extracellular Vesicles 6/3/2021 [PMID: 34122779]
F Michielin, GG Giobbe, C Luni, Q Hu, I Maroni, MR Orford, A Manfredi, L Di Filippo, AL David, D Cacchiarel, P De Coppi, S Eaton, N Elvassore The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs Cell Rep, 2020-12-01;33(9):108453. 2020-12-01 [PMID: 33264615] (ICC, IHC, Human)	ICC, IHC	Human
M Golizeh, K Winter, L Roussel, M Landekic, M Langelier, VG Loo, M Ndao, DC Vinh Fecal host biomarkers predicting severity of Clostridioides difficile infection JCI Insight, 2021-01-11;0(0):. 2021-01-11 [PMID: 33232301] (Western Blot, Human)	Western Blot	Human
Cao J, O'Day DR, Pliner HA et al. A human cell atlas of fetal gene expression Science 11/13/2020 [PMID: 33184181]
J Liu, T Pan, Y Chen, Y Liu, F Yang, Q Chen, N Abbas, M Zhong, Q Zhang, Y Xu, YX Li Repair of acute liver damage with immune evasive hESC derived hepato-blasts Stem Cell Res, 2020-09-26;49(0):102010. 2020-09-26 [PMID: 33011360] (ICC, IHC, Human, Mouse)	ICC, IHC	Human, Mouse
G Sorrentino, S Rezakhani, E Yildiz, S Nuciforo, MH Heim, MP Lutolf, K Schoonjans Mechano-modulatory synthetic niches for liver organoid derivation Nat Commun, 2020-07-10;11(1):3416. 2020-07-10 [PMID: 32651372] (ICC, Human)	ICC	Human
PA Subramani, N Vartak-Sha, S Sreekumar, P Mathur, B Nayer, S Dakhore, SK Basavanna, DM Kalappa, RV Krishnamur, B Mukhi, P Mishra, N Yoshida, SK Ghosh, R Shandil, S Narayanan, B Campo, K Hasegawa, AR Anvikar, N Valecha, V Sundaramur Plasmodium vivax liver stage assay platforms using Indian clinical isolates Malar. J., 2020-06-22;19(1):214. 2020-06-22 [PMID: 32571333] (ICC, Human)	ICC	Human
M Mehdipour, C Skinner, N Wong, M Lieb, C Liu, J Etienne, C Kato, D Kiprov, MJ Conboy, IM Conboy Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin Aging (Albany NY), 2020-05-30;12(10):8790-8819. 2020-05-30 [PMID: 32474458] (IHC, Western Blot, Human, Mouse)	IHC, Western Blot	Human, Mouse
N Mori, Y Akagi, Y Imai, Y Takayama, YS Kida Fabrication of Perfusable Vascular Channels and Capillaries in 3D Liver-like Tissue Sci Rep, 2020-04-14;10(1):5646. 2020-04-14 [PMID: 32286353] (IHC, Human)	IHC	Human
Musante L, Bontha Sv, La Salvia S et Al. Rigorous characterization of urinary extracellular vesicles (uEVs) in the low centrifugation pellet - a neglected source for uEVs Sci Rep 2/28/2020 [PMID: 32111925] Details: Antibody was used in Western Blot analysis to verify that subcellular contaminants were not interfering with detecting target bio-markers.
Cao-Sang Truong, Eunhui Seo, Hee-Sook Jun Psoralea corylifolia L. Seed Extract Attenuates Methylglyoxal-Induced Insulin Resistance by Inhibition of Advanced Glycation End Product Formation Oxidative Medicine and Cellular Longevity 12/30/2019 [PMID: 31976027]
ES Famulari, V Navarro-Ta, MB Herrera Sa, G Bortolussi, M Gai, L Conti, L Silengo, E Tolosano, C Tetta, AF Muro, G Camussi, S Fagoonee, F Altruda Human liver stem cells express UGT1A1 and improve phenotype of immunocompromised Crigler Najjar syndrome type I mice Sci Rep, 2020-01-21;10(1):887. 2020-01-21 [PMID: 31965023] (ICC, Human)	ICC	Human
Kang Wang, Fuhua Xu, Shawn P. Campbell, Kyle D. Hart, Tyler Durham, James Maylie et al. Rapid actions of anti‐Müllerian hormone in regulating synaptic transmission and long‐term synaptic plasticity in the hippocampus The FASEB Journal 1/1/2020 [PMID: 31914642]
C Lipps, P Northe, R Figueiredo, M Rohde, A Brahmer, EM Krämer-Alb, C Liebetrau, CB Wiedenroth, E Mayer, SD Kriechbaum, O Dörr, H Nef, CW Hamm, T Keller, C Troidl Non-Invasive Approach for Evaluation of Pulmonary Hypertension Using Extracellular Vesicle-Associated Small Non-Coding RNA Biomolecules, 2019-10-29;9(11):. 10/29/2019 [PMID: 31671920]
F Tonon, GG Giobbe, A Zambon, C Luni, O Gagliano, A Floreani, G Grassi, N Elvassore In vitro metabolic zonation through oxygen gradient on a chip Sci Rep, 2019-09-19;9(1):13557. 2019-09-19 [PMID: 31537830] (ICC, Human)	ICC	Human
Melod Mehdipour, Jessy Etienne, Chia-Chien Chen, Ranveer Gathwala, Maryam Rehman, Cameron Kato et al. Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age Aging (Albany NY) 8/15/2019 [PMID: 31422380]
AC Brook, RH Jenkins, A Clayton, A Kift-Morga, AC Raby, AP Shephard, B Mariotti, SM Cuff, F Bazzoni, T Bowen, DJ Fraser, M Eberl Neutrophil-derived miR-223 as local biomarker of bacterial peritonitis Sci Rep, 2019-07-12;9(1):10136. 2019-07-12 [PMID: 31300703] (ELISA Detection, Human)	ELISA Detection	Human
C Gu, P Li, W Liu, Y Zhou, WS Tan The role of insulin in transdifferentiated hepatocyte proliferation and function in serum-free medium J. Cell. Mol. Med., 2019-04-04;0(0):. 2019-04-04 [PMID: 30950200] (Western Blot, Human)	Western Blot	Human
H Okada, C Nakanishi, S Yoshida, M Shimojima, J Yokawa, M Mori, H Tada, T Yoshimuta, K Hayashi, T Yamano, R Hanayama, M Yamagishi, MA Kawashiri Function and Immunogenicity of Gene-corrected iPSC-derived Hepatocyte-Like Cells in Restoring Low Density Lipoprotein Uptake in Homozygous Familial Hypercholesterolemia Sci Rep, 2019-03-18;9(1):4695. 2019-03-18 [PMID: 30886174] (ICC, Human)	ICC	Human
Marcus Grohmann, Florian Wiede, Garron T. Dodd, Esteban N. Gurzov, Geraldine J. Ooi, Tariq Butt et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC Cell 11/15/2018 [PMID: 30454647]
A Fernández-, M Ortega-Rib, S Guixé-Munt, J Gracia-San 4 in 1: Antibody-free protocol for isolating the main hepatic cells from healthy and cirrhotic single rat livers J. Cell. Mol. Med., 2018-11-12;0(0):. 2018-11-12 [PMID: 30417530] (ICC, Rat)	ICC	Rat
A Skrzypczyk, S Kehr, I Krystel, SH Bernhart, S Giri, A Bader, PF Stadler Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes Stem Cells Int, 2018-08-19;2018(0):5692840. 2018-08-19 [PMID: 30210551] (ICC, Human)	ICC	Human
何琼, Qiong He, 王惠荟, 程涛, 袁卫平, 马钰波 et al. Genetic Correction and Hepatic Differentiation of Hemophilia B-specific Human Induced Pluripotent Stem Cells Chinese Medical Sciences Journal 9/27/2017 [PMID: 28956740]
MB Herrera Sa, S Previdi, S Bruno, V Fonsato, MC Deregibus, S Kholia, S Petrillo, E Tolosano, R Critelli, M Spada, R Romagnoli, M Salizzoni, C Tetta, G Camussi Extracellular vesicles from human liver stem cells restore argininosuccinate synthase deficiency Stem Cell Res Ther, 2017-07-27;8(1):176. 2017-07-27 [PMID: 28750687] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
CI Real, M Werner, A Paul, G Gerken, JF Schlaak, A Vaillant, R Broering Nucleic acid-based polymers effective against hepatitis B Virus infection in patients don't harbor immunostimulatory properties in primary isolated liver cells Sci Rep, 2017-03-08;7(0):43838. 2017-03-08 [PMID: 28272460] (ICC, Human)	ICC	Human
JM Delhove, SM Buckley, DP Perocheau, R Karda, P Arbuthnot, NC Henderson, SN Waddington, TR McKay Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice Sci Rep, 2017-02-03;7(0):41874. 2/3/2017 [PMID: 28157201]
A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood Nat Commun, 2016-11-22;7(0):13363. 2016-11-22 [PMID: 27874859] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Effect of Secreted Molecules of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells on Acute Hepatic Failure Model Stem Cells Dev, 2016-10-27;0(0):. 2016-10-27 [PMID: 27676103] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Kerim B. Kaylan, Viktoriya Ermilova, Ravi Chandra Yada, Gregory H. Underhill Combinatorial microenvironmental regulation of liver progenitor differentiation by Notch ligands, TGF beta , and extracellular matrix Scientific Reports 3/30/2016 [PMID: 27025873]
Park H, Choi Y, Kim J, Chun H, Im I, Yoon S, Han Y, Song C, Kim H Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary Hepatocytes. PLoS ONE, 2015-07-15;10(7):e0132992. 2015-07-15 [PMID: 26177506] (Flow Cytometry, Human)	Flow Cytometry	Human
Hongyan Zhou, Hector Martinez, Bruce Sun, Aiqun Li, Matthew Zimmer, Nicholas Katsanis et al. Rapid and Efficient Generation of Transgene-Free iPSC from a Small Volume of Cryopreserved Blood Stem Cell Reviews and Reports 8/1/2015 [PMID: 25951995]
Victor Navarro-Tableros, Maria Beatriz Herrera Sanchez, Federico Figliolini, Renato Romagnoli, Ciro Tetta, Giovanni Camussi Recellularization of Rat Liver Scaffolds by Human Liver Stem Cells Tissue Engineering Part A 6/1/2015 [PMID: 25794768]
Elmes M, Kaczocha M, Berger W, Leung K, Ralph B, Wang L, Sweeney J, Miyauchi J, Tsirka S, Ojima I, Deutsch D Fatty acid-binding proteins (FABPs) are intracellular carriers for Delta9-tetrahydrocannabinol (THC) and cannabidiol (CBD). J Biol Chem, 2015-02-09;290(14):8711-21. 2015-02-09 [PMID: 25666611] (IHC, Mouse)	IHC	Mouse
Kohei Yamamizu, David Schlessinger, Minoru S. H. Ko SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1) Development 11/15/2014 [PMID: 25371362]
I. A. Muchkaeva, E. B. Dashinimaev, A. S. Artyuhov, E. P. Myagkova, E. A. Vorotelyak, Y. Y. Yegorov et al. Generation of iPS Cells from Human Hair Follice Dermal Papilla Cells Acta Naturae 4/29/2014 [PMID: 24772326]
Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports, 2013-11-27;1(6):545-59. 2013-11-27 [PMID: 24371809] (ICC, Mouse)	ICC	Mouse
Hannan , Nicholas, Segeritz , Charis-P, Touboul , Thomas, Vallier , Ludovic Production of hepatocyte-like cells from human pluripotent stem cells. Nat Protoc, 2013-01-01;8(2):430-7. 2013-01-01 [PMID: 23370178] (ICC, Human)	ICC	Human
Byun K, Bayarsaikhan E, Kim D, Kim CY, Mook-Jung I, Paek SH, Kim SU, Yamamoto T, Won MH, Song BJ, Park YM, Lee B Induction of neuronal death by microglial AGE-albumin: implications for Alzheimer's disease. PLoS ONE, 2012-05-25;7(5):e37917. 2012-05-25 [PMID: 22662249] (ICC, Human)	ICC	Human
Youngmi Jung, Rafal P. Witek, Wing-Kin Syn, Steve S. Choi, Alessia Omenetti, Richard Premont et al. Signals from dying hepatocytes trigger growth of liver progenitors Gut 4/1/2013 [PMID: 20427400]
Hoang S, Liauw J, Choi M Netrin-4 enhances angiogenesis and neurologic outcome after cerebral ischemia. J. Cereb. Blood Flow Metab., 2008-11-05;29(2):385-97. 2008-11-05 [PMID: 18985053] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Yang L, Jung Y, Omenetti A, Witek RP, Choi S, Vandongen HM, Huang J, Alpini GD, Diehl AM Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers. Stem Cells, 2008-05-29;26(8):2104-13. 2008-05-29 [PMID: 18511600] (ICC, Mouse)	ICC	Mouse
Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, Kalluri R Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J. Biol. Chem., 2007-06-11;282(32):23337-47. 2007-06-11 [PMID: 17562716] (ICC, Mouse)	ICC	Mouse
Ilancheran S, Michalska A, Peh G, Wallace EM, Pera M, Manuelpillai U Stem cells derived from human fetal membranes display multilineage differentiation potential. Biol. Reprod., 2007-05-09;77(3):577-88. 2007-05-09 [PMID: 17494917] (ICC, Human)	ICC	Human
Herrera MB, Bruno S, Buttiglieri S, Tetta C, Gatti S, Deregibus MC, Bussolati B, Camussi G Isolation and characterization of a stem cell population from adult human liver. Stem Cells, 2006-08-31;24(12):2840-50. 2006-08-31 [PMID: 16945998] (ICC, Human)	ICC	Human
Baharvand H, Hashemi SM, Kazemi Ashtiani S, Farrokhi A Differentiation of human embryonic stem cells into hepatocytes in 2D and 3D culture systems in vitro. Int. J. Dev. Biol., 2006-01-01;50(7):645-52. 2006-01-01 [PMID: 16892178] (ICC, Human)	ICC	Human
Show All 54 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	ICC	Pig	12/05/2016	View Summary Application Immunocytochemistry Sample Tested pig trabecular meshwork cells Species Pig
	4 reviewed by: Verified Customer	Flow	Mouse	02/10/2015	View Summary Application Flow Cytometry Sample Tested See PMID 23072626 Species Mouse
	4 reviewed by: Verified Customer	Flow	Human	02/10/2015	View Summary Application Flow Cytometry Sample Tested See PMID 22829291 Species Human

Array MAB1455

• Albumin Antibodies
• Albumin Antibody Pair
• Albumin ELISA Kits
• Albumin Proteins
• Albumin ELISA