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STK4 Antibody [DyLight 650]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 650

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STK4 Antibody [DyLight 650] Summary

Immunogen
The immunogen recognized by this antibody maps to the C-terminus of human Mammalian Sterile 20-like 1 (Serine/Threonine Kinase 4) using the numbering given in Swiss Prot entry Q13043 (GeneID 6789).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STK4
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for STK4 Antibody [DyLight 650]

  • EC 2.7.11
  • EC 2.7.11.1
  • kinase responsive to stress 2
  • KRS2KRS2))
  • Mammalian STE20-like protein kinase 1
  • mammalian sterile 20-like 1
  • MST-1
  • MST1DKFZp686A2068
  • serine/threonine kinase 4
  • serine/threonine-protein kinase 4
  • Serine/threonine-protein kinase Krs-2
  • STE20-like kinase MST1

Background

STK4 is encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol STK4