STK38 Antibody (2G8-1F3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

STK38 belongs to the NDR family of serine/threonine protein kinases. NDR kinases require the phosphorylation of conserved Ser/Thr residues for activation. NDR family members have two unique stretches of primary sequence: an N-terminal regulatory (NTR) domain and an insert of several residues between subdomains VII and VIII of the kinase domain. The kinase domain insert functions as an auto-inhibitory sequence (AIS), while binding of the co-activator MOB (Mps-one binder) proteins to the NTR domain releases NDR kinases from inhibition of autophosphorylation. STK38 negatively regulates the activation of MEKK1/2 by direct interaction with the catalytic domain of MEKK1/2. The negative regulation of MEKK1/2 is not due to its phosphorylation by STK38.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publication 1 - 1 of 1.

Publication using H00011329-M01	Applications	Species
Zhou Y, Adolfs Y, Pijnappel WW et al. MICAL-1 is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis. Mol Cell Biol. 2011-07-05 [PMID: 21730291]

Array H00011329-M01

• STK38 Antibodies
• STK38 Lysate
• STK38 Protein