Detects human and rat SOX10. Epitope-mapping experiments indicated that clone 20B7 recognizes a determinant in the first 65 amino acids, which contains sequences unique to SOX10 (1).
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SOX10
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for SOX10 Antibody (20B7) [NL557]
DOM
MGC15649
PCWH
SOX10
SRY (sex determining region Y)-box 10
SRY-related HMG-box gene 10
transcription factor SOX-10
WS4
WS4C
WS4mouse, human homolog of
Background
SOX10 belongs to the SOX family of transcription factors which display
diverse roles during development. In the central nervous system, SOX10
is required for the terminal differentiation of oligodendrocytes and
myelination. In the peripheral nervous system, SOX10 maintains
pluripotency of neural crest stem cells and suppresses neuronal
differentiation.
Lo, L. et al. (2002) Development 129:1553.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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