Endothelin-3 Antibody (2A6-2A4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using H00001908-M01	Applications	Species
Zhu P, Li X, Liu Y et al. Methylation-mediated silencing of EDN3 promotes cervical cancer proliferation, migration and invasion Frontiers in oncology 2023-02-03 [PMID: 36824133] (WB, Human) Details: Overexpression of EDN3	WB	Human
Halbert D, Domenyuk V, Spetzler D et al. Aptamers and uses thereof United States Patent Application US 9958448 B2 2018-01-01

Array H00001908-M01

• Endothelin-3 Antibodies
• Endothelin-3 Lysates
• Endothelin-3 Protein