Western Blot: RUNX3/CBFA3 Antibody [NBP2-38863] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: Human cell line SK-MEL-30
Orthogonal Strategies: Immunohistochemistry-Paraffin: RUNX3/CBFA3 Antibody [NBP2-38863] - Staining in human lymph node and cerebral cortex tissues using anti-RUNX3 antibody. Corresponding RUNX3 RNA-seq data are ...read more
Immunohistochemistry-Paraffin: RUNX3/CBFA3 Antibody [NBP2-38863] - Staining of human cerebral cortex shows low expression as expected.
Immunohistochemistry-Paraffin: RUNX3/CBFA3 Antibody [NBP2-38863] - Staining of human lymph node shows high expression.
Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (87%)
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for RUNX3/CBFA3 Antibody
Acute myeloid leukemia 2 protein
AML2
AML2SL3/AKV core-binding factor alpha C subunit
CBFA3
CBFA3MGC16070
CBF-alpha-3
PEA2 alpha C
PEA2-alpha C
PEBP2 alpha C
PEBP2A3
PEBP2A3FLJ34510
PEBP2AC
PEBP2-alpha C
runt domain, alpha subunit 3
runt-related transcription factor 3
RUNX3
SL3-3 enhancer factor 1 alpha C subunit
transcription factor AML2
Background
RUNX3 binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. RUNX3 consists of a heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer through the Runt domain. DNA-binding is increased by heterodimerization.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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