Species: Hu, Mu
Applications: WB, Simple Western, CyTOF-ready, Flow, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Flow, IHC
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
RUNX3 binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. RUNX3 consists of a heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer through the Runt domain. DNA-binding is increased by heterodimerization.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
Rat
|
| Product By Gene ID |
864 |
| Alternate Names |
- Acute myeloid leukemia 2 protein
- AML2SL3/AKV core-binding factor alpha C subunit
- CBFA3MGC16070
- CBF-alpha-3
- PEA2 alpha C
- PEA2-alpha C
- PEBP2 alpha C
- PEBP2A3FLJ34510
- PEBP2-alpha C
- runt domain, alpha subunit 3
- runt-related transcription factor 3
- SL3-3 enhancer factor 1 alpha C subunit
- transcription factor AML2
|
![Intracellular Staining by Flow Cytometry RUNX3/CBFA3 Antibody (527327) [Unconjugated]](http://images.novusbio.com/fullsize2/RUNX3_MAB3765_Flow_Cytometry_8418.jpg)
![Immunocytochemistry RUNX3/CBFA3 Antibody (527327) [Unconjugated]](http://images.novusbio.com/fullsize2/RUNX3_MAB3765_Immunocytochemistry_10636.jpg)
![Western Blot RUNX3/CBFA3 Antibody (527327) [Unconjugated]](http://images.novusbio.com/fullsize2/RUNX3_MAB3765_Western_Blot_10662.jpg)
![Simple Western RUNX3/CBFA3 Antibody (527327) [Unconjugated]](http://images.novusbio.com/fullsize2/16364.jpg)
