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Proteasome subunit beta type 4 Antibody

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Western Blot: Proteasome subunit beta type 4 Antibody [NBP1-54592] - WB analysis of Proteasome subunit beta type 4 in rat whole brain extract. Image courtesy of anonymous customer product review.
Western Blot: Proteasome subunit beta type 4 Antibody [NBP1-54592] - WB analysis of Proteasome subunit beta type 4 in rat whole brain extract. Image courtesy of anonymous customer product review.
Western Blot: Proteasome subunit beta type 4 Antibody [NBP1-54592] - Titration: 0.2-1 ug/ml, Positive Control: HepG2 cell lysate.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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Proteasome subunit beta type 4 Antibody Summary

Description
The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Immunogen
Synthetic peptides corresponding to PSMB4(proteasome (prosome, macropain) subunit, beta type, 4) The peptide sequence was selected from the middle region of PSMB4 (NP_002787). Peptide sequence YLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMV. The peptide sequence for this immunogen was taken from within the described region.
Specificity
This product is specific to Subunit or Isoform: beta type-4.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PSMB4
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
Theoretical MW
29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 4
using
NBP1-54592 in the following application:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for Proteasome subunit beta type 4 Antibody

  • EC 3.4.25.1
  • HN3
  • HsBPROS26
  • HsN3
  • Macropain beta chain
  • Multicatalytic endopeptidase complex beta chain
  • PROS26
  • PROS-26
  • PROS26PROS-26
  • proteasome (prosome, macropain) subunit, beta type, 4
  • Proteasome beta chain
  • Proteasome chain 3
  • Proteasome subunit beta type 4
  • proteasome subunit beta type-4
  • proteasome subunit HsN3
  • proteasome subunit, beta type, 4,26 kDa prosomal protein
  • PSMB4

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB4 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Proteasome subunit
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NBP1-54592
Proteasome subunit beta type 4 Antibody
Species: Hu, Rt
Applications: WB

Publications for Proteasome subunit beta type 4 Antibody (NBP1-54592) (0)

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Review for Proteasome subunit beta type 4 Antibody (NBP1-54592) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Rat.

Reviews using NBP1-54592:
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Images Ratings Applications Species Date Details
Western Blot Proteasome subunit beta type 4 NBP1-54592
Enlarge 		4
reviewed by:
Kara Mann
 WB Rat 09/06/2012
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Summary

ApplicationWestern Blot
Sample TestedRat whole brain extract
SpeciesRat
Lot259

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Recent Reviews

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Western Blot Proteasome subunit beta type 4 NBP1-54592
Enlarge
 Kara Mann
09/06/2012
Application: WB
Species: Rat
read this review

Bioinformatics

Gene Symbol PSMB4
Entrez
Uniprot