eIF4E [p Ser209] Antibody

eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Porcine.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NB100-81898	Applications	Species
Chen Y, Zhu H, McCauley SR et al. Diminished satellite cell fusion and S6K1 expression in myotubes derived from skeletal muscle of low birth weight neonatal pigs. Physiol Rep. 2017-02-01 [PMID: 28183860] (WB, Porcine)	WB	Porcine

Array NB100-81898

• eIF4E Antibodies
• eIF4E Lysate
• eIF4E Proteins