Toba, K;Yamada, A;Sasa, K;Shirota, T;Kamijo, R; Expression of Kielin/chordin-like protein is regulated by BMP-2 in osteoblasts Bone reports 2024-09-01 [PMID: 39139593] (Bioassay, Mouse) |
Bioassay |
Mouse |
Múnera, JO;Kechele, DO;Bouffi, C;Qu, N;Jing, R;Maity, P;Enriquez, JR;Han, L;Campbell, I;Mahe, MM;McCauley, HA;Zhang, X;Sundaram, N;Hudson, JR;Zarsozo-Lacoste, A;Pradhan, S;Tominaga, K;Sanchez, JG;Weiss, AA;Chatuvedi, P;Spence, JR;Hachimi, M;North, T;Daley, GQ;Mayhew, CN;Hu, YC;Takebe, T;Helmrath, MA;Wells, JM; Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon Cell stem cell 2023-11-02 [PMID: 37922878] (Cell Culture) |
Cell Culture |
|
Miguez, P;De Paiva Goncalves, V;Musskopf, M;Rivera-Concepcion, A;McGaughey, S;Yu, C;Lee, DJ;Tui, S; Mitigation of BMP-induced Inflammation in Craniofacial Bone Regeneration and Improvement of Bone Parameters by Dietary Hesperidin Research square 2023-09-29 [PMID: 37841854] (In Vivo, Rat) |
In Vivo |
Rat |
Erdem, C;Gross, SM;Heiser, LM;Birtwistle, MR; MOBILE pipeline enables identification of context-specific networks and regulatory mechanisms Nature communications 2023-07-06 [PMID: 37414767] (Bioassay, Human) |
Bioassay |
Human |
Lin, M;Hartl, K;Heuberger, J;Beccaceci, G;Berger, H;Li, H;Liu, L;M�llerke, S;Conrad, T;Heymann, F;Woehler, A;Tacke, F;Rajewsky, N;Sigal, M; Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche Nature communications 2023-05-25 [PMID: 37230989] (Bioassay, Mouse) |
Bioassay |
Mouse |
Nagasaki, K;Yamada, A;Sasa, K;Kamijo, R; Kielin/chordin-like protein enhances induction of osteoblast differentiation by Bone Morphogenetic Protein-2 FEBS open bio 2023-05-25 [PMID: 37226930] (Differentiation, Mouse) |
Differentiation |
Mouse |
S Das, A Mondal, C Dey, S Chakrabort, R Bhowmik, S Karmakar, A Sengupta ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival The Journal of Biological Chemistry, 2023-02-16;0(0):103031. 2023-02-16 [PMID: 36805334] (Bioassay, Rat) |
Bioassay |
Rat |
Y Hachinohe, M Taira, M Hoshi, D Yoshida, W Hatakeyama, T Sawada, H Kondo Self-Prepared Hyaluronic Acid/Alkaline Gelatin Composite with Nano-Hydroxyapatite and Bone Morphogenetic Protein for Cranial Bone Formation International Journal of Molecular Sciences, 2023-01-06;24(2):. 2023-01-06 [PMID: 36674618] (In Vivo, Rat) |
In Vivo |
Rat |
Y Hachinohe, M Taira, M Hoshi, W Hatakeyama, T Sawada, H Kondo Bone Formation on Murine Cranial Bone by Injectable Cross-Linked Hyaluronic Acid Containing Nano-Hydroxyapatite and Bone Morphogenetic Protein Polymers, 2022-12-08;14(24):. 2022-12-08 [PMID: 36559734] (In Vivo, Mouse) |
In Vivo |
Mouse |
Z Shonibare, M Monavarian, K O'Connell, D Altomare, A Shelton, S Mehta, R Jaskula-Sz, R Phaeton, MD Starr, R Whitaker, A Berchuck, AB Nixon, RC Arend, NY Lee, CR Miller, N Hempel, K Mythreye Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer Oncogene, 2022-07-26;40(4):111066. 2022-07-26 [PMID: 35905726] (Bioassay, Human) |
Bioassay |
Human |
R Chowdhury, A Roure, Y le Pétillo, H Mayeur, V Daric, S Darras Highly distinct genetic programs for peripheral nervous system formation in chordates Bmc Biology, 2022-06-27;20(1):152. 2022-06-27 [PMID: 35761237] (Bioassay, Phallusia mammillata) |
Bioassay |
Phallusia mammillata |
M Vora, A Mondal, D Jia, P Gaddipati, M Akel, J Gilleran, J Roberge, C Rongo, J Langenfeld Bone morphogenetic protein signaling regulation of AMPK and PI3K in lung cancer cells and C. elegans Cell & bioscience, 2022-05-31;12(1):76. 2022-05-31 [PMID: 35641992] (Bioassay, Human) |
Bioassay |
Human |
AP Leinroth, AJ Mirando, D Rouse, Y Kobayahsi, PR Tata, HE Rueckert, Y Liao, JT Long, JV Chakkalaka, MJ Hilton Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations Cell Reports, 2022-05-10;39(6):110785. 2022-05-10 [PMID: 35545045] (Bioassay, Mouse) |
Bioassay |
Mouse |
F Kawecki, J Jann, M Fortin, FA Auger, N Faucheux, J Fradette Preclinical Evaluation of BMP-9-Treated Human Bone-like Substitutes for Alveolar Ridge Preservation following Tooth Extraction International Journal of Molecular Sciences, 2022-03-18;23(6):. 2022-03-18 [PMID: 35328724] (Cell Culture, Human) |
Cell Culture |
Human |
S Nagel, C Pommerenke, C Meyer, RAF MacLeod The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia International Journal of Molecular Sciences, 2022-03-16;23(6):. 2022-03-16 [PMID: 35328612] (Cell Culture, Human) |
Cell Culture |
Human |
I López-Anto, C Contreras-, L Luque-Mart, A Carpintero, P González-M, I Palmero Dynamic regulation of myofibroblast phenotype in cellular senescence Aging Cell, 2022-03-09;0(0):e13580. 2022-03-09 [PMID: 35266275] (Bioassay, Human) |
Bioassay |
Human |
Hendrik Boog, Rebecca Medda, Elisabetta Ada Cavalcanti-Adam Single Cell Center of Mass for the Analysis of BMP Receptor Heterodimers Distributions Journal of Imaging 2021-10-20 [PMID: 34821850] (Bioassay, Human) |
Bioassay |
Human |
M Moncayo-Do, GA Rico-Llano, DA Garzón-Alv, J Becerra, R Visser, MR Fontanilla The Effect of Pore Directionality of Collagen Scaffolds on Cell Differentiation and In Vivo Osteogenesis Polymers, 2021-09-20;13(18):. 2021-09-20 [PMID: 34578088] (In Vivo, Rats) |
In Vivo |
Rats |
M Zheng, S Erhardt, D Ai, J Wang Bmp Signaling Regulates Hand1 in a Dose-Dependent Manner during Heart Development International Journal of Molecular Sciences, 2021-09-11;22(18):. 2021-09-11 [PMID: 34576009] (Bioassay, Mouse) |
Bioassay |
Mouse |
PR Gajjala, RK Kasam, D Soundarara, D Sinner, SK Huang, AG Jegga, SK Madala Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis JCI Insight, 2021-10-22;0(0):. 2021-10-22 [PMID: 34520400] (Bioassay, Human) |
Bioassay |
Human |
PS Briquez, HM Tsai, EA Watkins, JA Hubbell Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion Science Advances, 2021-06-11;7(24):. 2021-06-11 [PMID: 34117071] (ELISA Capture, Human) |
ELISA Capture |
Human |
VC Cheung, CY Peng, M Marini?, NJ Sakabe, I Aneas, VJ Lynch, C Ober, MA Nobrega, JA Kessler Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua Cell Reports, 2021-05-18;35(7):109138. 2021-05-18 [PMID: 34010658] (Bioassay, Human) |
Bioassay |
Human |
C Zhou, D Chen, J Ren, D Huang, R Li, H Luo, C Guan, Y Cao, W Wang FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex Journal of Cellular and Molecular Medicine, 2021-02-13;0(0):. 2021-02-13 [PMID: 33580754] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
K Hiraoka, H Inada, K Yanai, N Osumi Bone Morphogenetic Proteins Inhibit Ciliogenesis of Ependymal Cells in Vitro Tohoku J Exp Med, 2020-11-01;252(3):199-208. 2020-11-01 [PMID: 33087680] (Bioassay, Mouse) |
Bioassay |
Mouse |
BE Schwartz, V Rajagopal, C Smith, E Cohick, G Whissell, M Gamboa, R Pai, A Sigova, I Grossman, D Bumcrot, K Sasidharan, S Romeo, A Sehgal, P Pingitore Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings Cells, 2020-10-07;9(10):. 2020-10-07 [PMID: 33036387] (Bioassay, Human) |
Bioassay |
Human |
L Leiendecke, PS Jung, I Krecioch, T Neumann, A Schleiffer, K Mechtler, T Wiesner, AC Obenauf LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma EMBO Mol Med, 2020-10-07;0(0):e12525. 2020-10-07 [PMID: 33026191] (Bioassay, Human) |
Bioassay |
Human |
T Mang, K Kleinschmi, F Ploeger, A Schoeneman, S Lindemann, A Gigout BMPR1A is necessary for chondrogenesis and osteogenesis while BMPR1B prevents hypertrophic differentiation J. Cell. Sci., 2020-08-21;0(0):. 2020-08-21 [PMID: 32764110] (Surface Plasmon Resonance, Human) |
Surface Plasmon Resonance |
Human |
SK Meurer, O Tezcan, T Lammers, R Weiskirche Differential regulation of Lipocalin 2 (LCN2) in doxorubicin-resistant 4T1 triple negative breast cancer cells Cell. Signal., 2020-08-03;74(0):109731. 2020-08-03 [PMID: 32758668] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
L Meng, X Teng, Y Liu, C Yang, S Wang, W Yuan, J Meng, H Chi, L Duan, X Liu Vital Roles of Gremlin-1 in Pulmonary Arterial Hypertension Induced by Systemic-to-Pulmonary Shunts J Am Heart Assoc, 2020-07-31;9(15):e016586. 2020-07-31 [PMID: 32750294] (Bioassay, Rat) |
Bioassay |
Rat |
AS Ibrahim, K Hussein, F Wang, M Wan, N Saad, M Essa, I Kim, A Shakoor, LA Owen, MM DeAngelis, M Al-Shabraw Bone Morphogenetic Protein (BMP)4 But Not BMP2 Disrupts the Barrier Integrity of Retinal Pigment Epithelia and Induces Their Migration: A Potential Role in Neovascular Age-Related Macular Degeneration J Clin Med, 2020-07-19;9(7):. 2020-07-19 [PMID: 32707711] (Bioassay, Human) |
Bioassay |
Human |
A VanCleave, M Palmer, F Fang, H Torres, T Rodezno, Q Li, K Fuglsby, C Evans, Y Afeworki, A Ross, P Rao, P Leiferman, S Zheng, P Houghton, J Tao Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway Oncotarget, 2020-07-07;11(27):2597-2610. 2020-07-07 [PMID: 32676162] (Bioassay, Human) |
Bioassay |
Human |
S Qin, W Wang, Z Liu, X Hua, S Fu, F Dong, A Li, Z Liu, P Wang, L Dai, P Liang, J Zhang, W Cao, X Xiong, H Chen, J Xu Fibrochondrogenic differentiation potential of tendon-derived stem/progenitor cells from human patellar tendon J Orthop Translat, 2019-11-01;22(0):101-108. 2019-11-01 [PMID: 32440505] (Cell Culture, Human) |
Cell Culture |
Human |
A Dudakovic, RM Samsonraj, CR Paradise, C Galeano-Ga, MO Mol, D Galeano-Ga, P Zan, ML Galvan, M Hevesi, O Pichurin, R Thaler, DL Begun, P Kloen, M Karperien, AN Larson, JJ Westendorf, SM Cool, AJ van Wijnen Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2 J. Biol. Chem., 2020-04-24;0(0):. 2020-04-24 [PMID: 32332097] (Bioassay, Mouse) |
Bioassay |
Mouse |
A Krouwels, JD Iljas, AHM Kragten, WJA Dhert, FC Öner, MA Tryfonidou, LB Creemers Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration Int J Mol Sci, 2020-04-14;21(8):. 2020-04-14 [PMID: 32295299] (Bioassay, Human) |
Bioassay |
Human |
S Stich, M Jagielski, A Fleischman, C Meier, P Bussmann, B Kohl, J Schmidt, JP Krüger, M Endres, M Cabraja, K Reimann, D Laue, W Ertel, M Sittinger Degeneration of Lumbar Intervertebral Discs: Characterization of Anulus Fibrosus Tissue and Cells of Different Degeneration Grades Int J Mol Sci, 2020-03-21;21(6):. 2020-03-21 [PMID: 32245213] (Bioassay, Human) |
Bioassay |
Human |
DA Mázala, JS Novak, MW Hogarth, M Nearing, P Adusumalli, CB Tully, NF Habib, H Gordish-Dr, YW Chen, JK Jaiswal, TA Partridge TGF-&beta-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model JCI Insight, 2020-03-26;5(6):. 2020-03-26 [PMID: 32213706] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
R Castro-Viñ, C Sanjurjo-R, M Piñeiro-Ra, T Hermida-Gó, S Rodríguez-, N Oreiro, J de Toro, I Fuentes, FJ Blanco, S Díaz-Prado Generation and characterization of human induced pluripotent stem cells (iPSCs) from hand osteoarthritis patient-derived fibroblasts Sci Rep, 2020-03-06;10(1):4272. 2020-03-06 [PMID: 32144293] (Cell Culture, Human) |
Cell Culture |
Human |
TJ Broekelman, NK Bodmer, RP Mecham Identification of the growth factor binding sequence in the extracellular matrix protein MAGP-1 J. Biol. Chem., 2020-01-27;0(0):. 2020-01-27 [PMID: 31988245] (Surface Plasmon Resonance, N/A) |
Surface Plasmon Resonance |
N/A |
HJ Zhao, HM Chang, C Klausen, H Zhu, Y Li, PCK Leung Bone morphogenetic protein 2 induces the activation of WNT/beta-catenin signaling and human trophoblast invasion through up-regulating BAMBI Cell. Signal., 2019-11-28;0(0):109489. 2019-11-28 [PMID: 31786181] (Cell Culture, Human) |
Cell Culture |
Human |
D Seo, SM Jung, JS Park, J Lee, J Ha, M Kim, SH Park The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway EBioMedicine, 2019-11-01;49(0):55-71. 2019-11-01 [PMID: 31685442] (Cell Culture, Human) |
Cell Culture |
Human |
M Omi, V Kaartinen, Y Mishina Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD signaling pathway J. Biol. Chem., 2019-10-16;0(0):. 2019-10-16 [PMID: 31619522] (Bioassay, Mouse) |
Bioassay |
Mouse |
LR Dutton, CL O' Neill, RJ Medina, DP Brazil No evidence of Gremlin1-mediated activation of VEGFR2 signalling in endothelial cells J. Biol. Chem., 2019-10-11;0(0):. 2019-10-11 [PMID: 31604823] (Cell Culture, Human) |
Cell Culture |
Human |
J Ren, M Smid, J Iaria, DCF Salvatori, H van Dam, HJ Zhu, JWM Martens, P Ten Dijke Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression Breast Cancer Res., 2019-09-18;21(1):109. 2019-09-18 [PMID: 31533776] (Bioassay, Human) |
Bioassay |
Human |
Li, Y Jiang, H Lin, H Shen, J Sohn, PG Alexander, RS Tuan Muscle injury promotes heterotopic ossification by stimulating local bone morphogenetic protein-7 production J Orthop Translat, 2019-07-05;18(0):142-153. 2019-07-05 [PMID: 31508317] (In Vivo, Mouse) |
In Vivo |
Mouse |
K Krüger, S Schmid, F Paulsen, A Ignatius, P Klinger, T Hotfiel, B Swoboda, K Gelse Trefoil Factor 3 (TFF3) Is Involved in Cell Migration for Skeletal Repair Int J Mol Sci, 2019-09-01;20(17):. 2019-09-01 [PMID: 31480518] (Bioassay, Human) |
Bioassay |
Human |
S Moghadasi, A Koontz, G Tseropoulo, L Kerosuo, P Mehrotra, VK Bajpai, SR Selvam, P Lei, ME Bronner, ST Andreadis Neural crest stem cells from human epidermis of aged donors maintain their multipotency in vitro and in vivo Sci Rep, 2019-07-05;9(1):9750. 2019-07-05 [PMID: 31278326] (Bioassay, Human) |
Bioassay |
Human |
J Li, A Ayoub, Y Xiu, X Yin, JO Sanders, A Mesfin, L Xing, Z Yao, BF Boyce TGFbeta-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis Nat Commun, 2019-06-26;10(1):2795. 2019-06-26 [PMID: 31243287] (Bioassay, Mouse) |
Bioassay |
Mouse |
M Rosina, F Langone, G Giuliani, A Cerquone P, A Reggio, A Calderone, C Fuoco, L Castagnoli, C Gargioli, G Cesareni Osteogenic differentiation of skeletal muscle progenitor cells is activated by the DNA damage response Sci Rep, 2019-04-01;9(1):5447. 2019-04-01 [PMID: 30931986] (Bioassay, Mouse) |
Bioassay |
Mouse |
X Zhang, X Lin, T Liu, L Deng, Y Huang, Y Liu Osteogenic Enhancement Between Icariin and Bone Morphogenetic Protein 2: A Potential Osteogenic Compound for Bone Tissue Engineering Front Pharmacol, 2019-03-12;10(0):201. 2019-03-12 [PMID: 30914948] (Bioassay, Human) |
Bioassay |
Human |
HJ Kim, HJ Kim, Y Choi, MK Bae, DS Hwang, SH Shin, JY Lee Zoledronate Enhances Osteocyte-Mediated Osteoclast Differentiation by IL-6/RANKL Axis Int J Mol Sci, 2019-03-22;20(6):. 2019-03-22 [PMID: 30909508] (Bioassay, Mouse) |
Bioassay |
Mouse |
S Supakul, K Yao, H Ochi, T Shimada, K Hashimoto, S Sunamura, Y Mabuchi, M Tanaka, C Akazawa, T Nakamura, A Okawa, S Takeda, S Sato Pericytes as a Source of Osteogenic Cells in Bone Fracture Healing Int J Mol Sci, 2019-03-02;20(5):. 2019-03-02 [PMID: 30832329] (Bioassay, Mouse) |
Bioassay |
Mouse |
WKW Ho, L Freem, D Zhao, KJ Painter, TE Woolley, EA Gaffney, MJ McGrew, A Tzika, MC Milinkovit, P Schneider, A Drusko, F Matthäus, JD Glover, KL Wells, JA Johansson, MG Davey, HM Sang, M Clinton, DJ Headon Feather arrays are patterned by interacting signalling and cell density waves PLoS Biol., 2019-02-21;17(2):e3000132. 2019-02-21 [PMID: 30789897] (Bioassay, Chicken) |
Bioassay |
Chicken |
L Yu, LA Dawson, M Yan, K Zimmel, YL Lin, CP Dolan, M Han, K Muneoka BMP9 stimulates joint regeneration at digit amputation wounds in mice Nat Commun, 2019-02-05;10(1):424. 2019-02-05 [PMID: 30723209] (In Vivo, Mouse) |
In Vivo |
Mouse |
T Karakida, K Onuma, MM Saito, R Yamamoto, T Chiba, R Chiba, Y Hidaka, K Fujii-Abe, H Kawahara, Y Yamakoshi Potential for Drug Repositioning of Midazolam for Dentin Regeneration Int J Mol Sci, 2019-02-04;20(3):. 2019-02-04 [PMID: 30720745] (Bioassay, Porcine) |
Bioassay |
Porcine |
S Hendrikx, S Coso, B Prat-Luri, L Wetterwald, A Sabine, CA Franco, S Nassiri, N Zangger, H Gerhardt, M Delorenzi, TV Petrova Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2 Cell Rep, 2019-01-29;26(5):1227-1241.e6. 2019-01-29 [PMID: 30699351] (Bioassay, Mouse) |
Bioassay |
Mouse |
WN Addison, KC Hall, S Kokabu, T Matsubara, MM Fu, F Gori, R Baron Zfp423 Regulates Skeletal Muscle Regeneration and Proliferation Mol. Cell. Biol., 2019-04-02;0(0):. 2019-04-02 [PMID: 30692273] (Bioassay, Human) |
Bioassay |
Human |
M Subileau, G Merdzhanov, D Ciais, V Collin-Fau, JJ Feige, S Bailly, D Vittet Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation Stem Cell Reports, 2018-12-27;0(0):. 2018-12-27 [PMID: 30595547] (Bioassay, Mouse) |
Bioassay |
Mouse |
B Wang, Y Guo, X Chen, C Zeng, Q Hu, W Yin, W Li, H Xie, B Zhang, X Huang, F Yu Nanoparticle-modified chitosan-agarose-gelatin scaffold for sustained release of SDF-1 and BMP-2 Int J Nanomedicine, 2018-11-12;13(0):7395-7408. 2018-11-12 [PMID: 30519022] (Bioassay, Human) |
Bioassay |
Human |
K Oudina, J Paquet, A Moya, E Massouride, M Bensidhoum, N Larochette, M Deschepper, C Pinset, H Petite The paracrine effects of human induced pluripotent stem cells promote bone-like structures via the upregulation of BMP expression in a mouse ectopic model Sci Rep, 2018-11-20;8(1):17106. 2018-11-20 [PMID: 30459360] (Bioassay, Mouse) |
Bioassay |
Mouse |
SY Lee, ED Abel, F Long Glucose metabolism induced by Bmp signaling is essential for murine skeletal development Nat Commun, 2018-11-16;9(1):4831. 2018-11-16 [PMID: 30446646] (Bioassay, Mouse) |
Bioassay |
Mouse |
LS Pane, FG Fulcoli, A Cirino, A Altomonte, R Ferrentino, M Bilio, A Baldini Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer Dis Model Mech, 2018-08-30;11(9):. 2018-08-30 [PMID: 30166330] (Bioassay, Human) |
Bioassay |
Human |
K Sasa, K Yoshimura, A Yamada, D Suzuki, Y Miyamoto, H Imai, K Nagayama, K Maki, M Yamamoto, R Kamijo Monocarboxylate transporter-1 promotes osteoblast differentiation via suppression of p53, a negative regulator of osteoblast differentiation Sci Rep, 2018-07-12;8(1):10579. 2018-07-12 [PMID: 30002387] (Bioassay, Mouse) |
Bioassay |
Mouse |
K Koefoed, J Skat-Rørda, P Andersen, CB Warzecha, M Pye, TA Andersen, KD Ajbro, E Bendsen, M Narimatsu, F Vilhardt, LB Pedersen, JL Wrana, RH Anderson, K Møllgård, ST Christense, LA Larsen The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development Sci Rep, 2018-06-22;8(1):9542. 2018-06-22 [PMID: 29934521] (Bioassay, Human) |
Bioassay |
Human |
YH Chung, YH Huang, TH Chu, CL Chen, PR Lin, SC Huang, DC Wu, CC Huang, TH Hu, YH Kao, MH Tai BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-?1 signaling Lab. Invest., 2018-05-22;0(0):. 2018-05-22 [PMID: 29789683] (Bioassay, Rat) |
Bioassay |
Rat |
P Jongwattan, M Terajima, PA Miguez, W Querido, H Nagaoka, N Sumida, EG Gurysh, KM Ainslie, N Pleshko, L Perera, M Yamauchi Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function Sci Rep, 2018-05-04;8(1):7022. 2018-05-04 [PMID: 29728612] (Bioassay, Mouse) |
Bioassay |
Mouse |
H Kang, S Jha, Z Deng, N Fratzl-Zel, WA Cabral, A Ivovic, F Meylan, EP Hanson, E Lange, J Katz, P Roschger, K Klaushofer, EW Cowen, RM Siegel, JC Marini, T Bhattachar Somatic activating mutations in MAP2K1 cause melorheostosis Nat Commun, 2018-04-11;9(1):1390. 2018-04-11 [PMID: 29643386] (Bioassay, Human) |
Bioassay |
Human |
P Bozatzi, KS Dingwell, KZ Wu, F Cooper, TD Cummins, LD Hutchinson, J Vogt, NT Wood, TJ Macartney, J Varghese, R Gourlay, DG Campbell, JC Smith, GP Sapkota PAWS1 controls Wnt signalling through association with casein kinase 1? EMBO Rep., 2018-03-07;0(0):. 2018-03-07 [PMID: 29514862] (Bioassay, Human) |
Bioassay |
Human |
DM Burmeister, R Stone, N Wrice, A Laborde, SC Becerra, S Natesan, RJ Christy Delivery of Allogeneic Adipose Stem Cells in Polyethylene Glycol-Fibrin Hydrogels as an Adjunct to Meshed Autografts After Sharp Debridement of Deep Partial Thickness Burns Stem Cells Transl Med, 2018-02-18;0(0):. 2018-02-18 [PMID: 29457376] (Bioassay, Porcine) |
Bioassay |
Porcine |
M Desancé, R Contentin, L Bertoni, T Gomez-Ledu, T Branly, S Jacquet, JM Betsch, A Batho, F Legendre, F Audigié, P Galéra, M Demoor Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy Int J Mol Sci, 2018-02-10;19(2):. 2018-02-10 [PMID: 29439436] (Bioassay, Equine) |
Bioassay |
Equine |
S Kokabu, V Rosen BMP3 expression by osteoblast lineage cells is regulated by canonical Wnt signaling FEBS Open Bio, 2017-12-16;8(2):168-176. 2017-12-16 [PMID: 29435407] (Bioassay, Mouse) |
Bioassay |
Mouse |
JB Lees-Shepa, M Yamamoto, AA Biswas, SJ Stoessel, SE Nicholas, CA Cogswell, PM Devarakond, MJ Schneider, SM Cummins, NP Legendre, S Yamamoto, V Kaartinen, JW Hunter, DJ Goldhamer Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva Nat Commun, 2018-02-02;9(1):471. 2018-02-02 [PMID: 29396429] (In Vivo, Mouse) |
In Vivo |
Mouse |
WS Fagg, N Liu, MJ Yang, K Cheng, E Chung, JS Kim, G Wu, J Fair Magnetic Targeting of Stem Cell Derivatives Enhances Hepatic Engraftment into Structurally Normal Liver Cell Transplant, 2017-12-01;26(12):1868-1877. 2017-12-01 [PMID: 29390880] (Bioassay, Mouse) |
Bioassay |
Mouse |
DW Youngstrom, R Senos, RL Zondervan, JD Brodeur, AR Lints, DR Young, TL Mitchell, ME Moore, MH Myers, WJ Tseng, KM Loomes, KD Hankenson Intraoperative delivery of the Notch ligand Jagged-1 regenerates appendicular and craniofacial bone defects NPJ Regen Med, 2017-12-15;2(0):32. 2017-12-15 [PMID: 29302365] (In Vivo, Mouse) |
In Vivo |
Mouse |
MG Perino, S Yamanaka, DR Riordon, Y Tarasova, KR Boheler Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells PLoS ONE, 2017-12-12;12(12):e0188569. 2017-12-12 [PMID: 29232368] (Bioassay, Mouse) |
Bioassay |
Mouse |
Y Yu, S Gu, W Li, C Sun, F Chen, M Xiao, L Wang, D Xu, Y Li, C Ding, Z Xia, Y Li, S Ye, P Xu, B Zhao, J Qin, YG Chen, X Lin, XH Feng Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-? signaling Proc. Natl. Acad. Sci. U.S.A., 2017-09-05;0(0):. 2017-09-05 [PMID: 28874583] (Bioassay, Mouse) |
Bioassay |
Mouse |
SJ Bae, HJ Kim, HY Won, YK Min, ES Hwang Acceleration of osteoblast differentiation by a novel osteogenic compound, DMP-PYT, through activation of both the BMP and Wnt pathways Sci Rep, 2017-08-16;7(1):8455. 2017-08-16 [PMID: 28814721] (Bioassay, Mouse) |
Bioassay |
Mouse |
J Fan, J Pi-Anfruns, M Guo, DCS Im, ZK Cui, S Kim, BM Wu, TL Aghaloo, M Lee Small molecule-mediated tribbles homolog 3 promotes bone formation induced by bone morphogenetic protein-2 Sci Rep, 2017-08-08;7(1):7518. 2017-08-08 [PMID: 28790361] (Bioassay, Human) |
Bioassay |
Human |
C Sallon, I Callebaut, I Boulay, J Fontaine, D Logeart-Av, C Henriquet, M Pugnière, X Cayla, P Monget, G Harichaux, V Labas, S Canepa, C Taragnat Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells J. Biol. Chem., 2017-07-26;0(0):. 2017-07-26 [PMID: 28747434] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
S François, VV Eder, K Belmokhtar, MC Machet, L Douay, NC Gorin, M Benderitte, CA Alain Synergistic effect of human Bone Morphogenic Protein-2 and Mesenchymal Stromal Cells on chronic wounds through hypoxia-inducible factor-1 ? induction Sci Rep, 2017-06-27;7(1):4272. 2017-06-27 [PMID: 28655873] (Bioassay, Rat) |
Bioassay |
Rat |
JO Múnera, N Sundaram, SA Rankin, D Hill, C Watson, M Mahe, JE Vallance, NF Shroyer, KL Sinagoga, A Zarzoso-La, JR Hudson, JC Howell, P Chatuvedi, JR Spence, JM Shannon, AM Zorn, MA Helmrath, JM Wells Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling Cell Stem Cell, 2017-06-22;0(0):. 2017-06-22 [PMID: 28648364] (Bioassay, Human) |
Bioassay |
Human |
L Bai, HM Chang, JC Cheng, C Klausen, G Chu, PCK Leung, G Yang SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells Cell. Signal., 2017-05-31;37(0):52-61. 2017-05-31 [PMID: 28578012] (Bioassay, Human) |
Bioassay |
Human |
J Feng, J Jing, J Li, H Zhao, V Punj, T Zhang, J Xu, Y Chai BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice Development, 2017-06-02;0(0):. 2017-06-02 [PMID: 28576771] (Bioassay, Mouse) |
Bioassay |
Mouse |
YM Lin, J Lee, JFY Lim, M Choolani, JKY Chan, S Reuveny, SKW Oh Critical attributes of human early mesenchymal stromal cell-laden microcarrier constructs for improved chondrogenic differentiation Stem Cell Res Ther, 2017-05-08;8(1):93. 2017-05-08 [PMID: 28482913] (Bioassay, Human) |
Bioassay |
Human |
SJ Bae, YK Min, ES Hwang Potent osteogenic activity of a novel imidazobenzimidazole derivative, IBIP Biochem. Biophys. Res. Commun., 2017-04-15;487(2):409-414. 2017-04-15 [PMID: 28419840] (Bioassay, Mouse) |
Bioassay |
Mouse |
K Breitkopf-, C Meyer, C König, H Gaitantzi, A Addante, M Thomas, E Wiercinska, C Cai, Q Li, F Wan, C Hellerbran, NA Valous, M Hahnel, C Ehlting, JG Bode, S Müller-Boh, U Klingmülle, J Altenöder, I Ilkavets, MJ Goumans, LJ Hawinkels, SJ Lee, M Wieland, C Mogler, MP Ebert, B Herrera, H Augustin, A Sánchez, S Dooley, P Ten Dijke BMP-9 interferes with liver regeneration and promotes liver fibrosis Gut, 2017-03-23;0(0):. 2017-03-23 [PMID: 28336518] (Mouse) |
|
Mouse |
DW Hammers, M Merscham-B, JY Hsiao, S Engst, JJ Hartman, HL Sweeney Supraphysiological levels of GDF11 induce striated muscle atrophy EMBO Mol Med, 2017-04-01;0(0):. 2017-04-01 [PMID: 28270449] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
O Veraitch, Y Mabuchi, Y Matsuzaki, T Sasaki, H Okuno, A Tsukashima, M Amagai, H Okano, M Ohyama Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Sci Rep, 2017-02-21;7(0):42777. 2017-02-21 [PMID: 28220862] (Bioassay, Human) |
Bioassay |
Human |
ML Stevens, P Chaturvedi, SA Rankin, M Macdonald, S Jagannatha, M Yukawa, A Barski, AM Zorn Genomic integration of Wnt/?-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional program Development, 2017-02-20;0(0):. 2017-02-20 [PMID: 28219948] (Organoid Culture, Xenopus) |
Organoid Culture |
Xenopus |
A Riba, M Emmenlauer, A Chen, F Sigoillot, F Cong, C Dehio, J Jenkins, M Zavolan Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results Cell Syst, 2017-02-15;4(2):182-193.e4. 2017-02-15 [PMID: 28215525] (Bioassay, Human) |
Bioassay |
Human |
T Jung, JH Lee, S Park, YJ Kim, J Seo, HE Shim, KS Kim, HS Jang, HM Chung, SG Oh, SH Moon, SW Kang Effect of BMP-2 Delivery Mode on Osteogenic Differentiation of Stem Cells Stem Cells Int, 2017-01-19;2017(0):7859184. 2017-01-19 [PMID: 28197209] (Bioassay, Human) |
Bioassay |
Human |
SV Hegarty, AM Sullivan, GW O'Keeffe Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth Neurosci. Lett, 2017-02-08;643(0):32-37. 2017-02-08 [PMID: 28188849] (Bioassay, Human) |
Bioassay |
Human |
S Sripathy, V Leko, RL Adrianse, T Loe, EJ Foss, E Dalrymple, U Lao, T Gatbonton-, KT Carter, B Payer, PJ Paddison, WM Grady, JT Lee, MS Bartolomei, A Bedalov Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-? superfamily as a regulator of XIST expression Proc. Natl. Acad. Sci. U.S.A, 2017-01-31;0(0):. 2017-01-31 [PMID: 28143937] (Bioassay, Mouse) |
Bioassay |
Mouse |
Atakan Tevlek Bi-layered constructs of poly(glycerol-sebacate)-?-tricalcium phosphate for bone-soft tissue interface applications Mater Sci Eng C Mater Biol Appl, 2016-11-27;72(0):316-324. 2016-11-27 [PMID: 28024592] (Bioassay, Mouse) |
Bioassay |
Mouse |
Yan-Ting Wu Bone morphogenetic protein 2 regulates cell-cell communication by down-regulating connexin43 expression in luteinized human granulosa cells Mol. Hum. Reprod, 2017-03-01;0(0):. 2017-03-01 [PMID: 27986931] (Bioassay, Human) |
Bioassay |
Human |
Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication PLoS ONE, 2016-12-15;11(12):e0168334. 2016-12-15 [PMID: 27977771] (Bioassay, Human) |
Bioassay |
Human |
G B de Souza Bovine ovarian stem cells differentiate into germ cells and oocyte-like structures after culture in vitro Reprod. Domest. Anim, 2016-12-07;0(0):. 2016-12-07 [PMID: 27925309] (Bioassay, Bovine) |
Bioassay |
Bovine |
Regulation of hepcidin expression by inflammation-induced activin B Sci Rep, 2016-12-06;6(0):38702. 2016-12-06 [PMID: 27922109] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6 Nat Commun, 2016-11-11;7(0):13247. 2016-11-11 [PMID: 27834400] (Bioassay, Human) |
Bioassay |
Human |
Katsuhiro Hiranuma, Atsushi Yamada, Tamaki Kurosawa, Ryo Aizawa, Dai Suzuki, Yoshiro Saito, Ryo Nagahama, Mikiko Ikehata, Masayuki Tsukasaki, Naoko Morimura, Daichi Chikazu, Koutaro Maki, Tatsuo Shirota, Masamichi Takami, Matsuo Yamamoto, Takehiko Iijima, Ryutaro Kamijo Expression of nephronectin is enhanced by 1?,25-dihydroxyvitamin D3. FEBS Open Bio, 2016-07-13;0(0):2211-5463. 2016-07-13 [PMID: 27642554] (Bioassay, Mouse) |
Bioassay |
Mouse |
Mesenchymal stem cells from cortical bone demonstrate increased clonal incidence, potency, and developmental capacity compared to their bone marrow-derived counterparts J Tissue Eng, 2016-08-16;7(0):2041731416661. 2016-08-16 [PMID: 27579159] (In Vivo, Rat) |
In Vivo |
Rat |
Rachel Ruoff Cell type-specific control of protein synthesis and proliferation by FGF-dependent signaling to the translation repressor 4E-BP Proc Natl Acad Sci USA, 2016-06-16;0(0):. 2016-06-16 [PMID: 27313212] (Bioassay, Mouse) |
Bioassay |
Mouse |
CM Karner, E Esen, J Chen, FF Hsu, J Turk, F Long Wnt Protein Signaling Reduces Nuclear Acetyl-CoA Levels to Suppress Gene Expression during Osteoblast Differentiation J. Biol. Chem., 2016-04-20;291(25):13028-39. 2016-04-20 [PMID: 27129247] (Bioassay, Mouse) |
Bioassay |
Mouse |
Chang C, Yeh S, Lee B, Chen C, Su C, Lin Y, Liu C, Chen H Osteogenic Surface Modification Based on Functionalized Poly-P-Xylylene Coating. PLoS ONE, 2015-09-17;10(9):e0137017. 2015-09-17 [PMID: 26379273] (Bioassay, Transgenic Mouse) |
Bioassay |
Transgenic Mouse |
Cruet-Hennequart S, Drougard C, Shaw G, Legendre F, Demoor M, Barry F, Lefaix J, Galera P Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells. PLoS ONE, 2015-04-02;10(3):e0119334. 2015-04-02 [PMID: 25837977] (Bioassay, Human) |
Bioassay |
Human |
Westhrin M, Xie M, Olderoy M, Sikorski P, Strand B, Standal T Osteogenic differentiation of human mesenchymal stem cells in mineralized alginate matrices. PLoS ONE, 2015-03-13;10(3):e0120374. 2015-03-13 [PMID: 25769043] (Bioassay, Human) |
Bioassay |
Human |
Nio-Kobayashi J, Trendell J, Giakoumelou S, Boswell L, Nicol L, Kudo M, Sakuragi N, Iwanaga T, Duncan W Bone morphogenetic proteins are mediators of luteolysis in the human corpus luteum. Endocrinology, 2015-01-30;156(4):1494-503. 2015-01-30 [PMID: 25635621] (Bioassay, Human) |
Bioassay |
Human |
Malhotra , Rajeev, Burke , Megan F, Martyn , Trejeeve, Shakartzi , Hannah R, Thayer , Timothy, O'Rourke , Caitlin, Li , Pingchen, Derwall , Matthias, Spagnolli , Ester, Kolodziej , Starsha, Hoeft , Konrad, Mayeur , Claire, Jiramongkolchai , Pawina, Kumar , Ravindra, Buys , Emmanuel, Yu , Paul B, Bloch , Kenneth, Bloch , Donald B Inhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency. PLoS ONE, 2015-01-20;10(1):e0117098. 2015-01-20 [PMID: 25603410] (Bioassay, Mouse) |
Bioassay |
Mouse |
Prewitt A, Ghose S, Frump A, Datta A, Austin E, Kenworthy A, de Caestecker M Heterozygous null bone morphogenetic protein receptor type 2 mutations promote SRC kinase-dependent caveolar trafficking defects and endothelial dysfunction in pulmonary arterial hypertension. J Biol Chem, 2014-11-19;290(2):960-71. 2014-11-19 [PMID: 25411245] (Bioassay, Mouse) |
Bioassay |
Mouse |
Hill C, Jacobs B, Brown C, Barnett J, Goudy S Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis. Dev Dyn, 2014-12-01;244(2):122-33. 2014-12-01 [PMID: 25382630] (Bioassay, Mouse) |
Bioassay |
Mouse |
Alberton P, Dex S, Popov C, Shukunami C, Schieker M, Docheva D Loss of tenomodulin results in reduced self-renewal and augmented senescence of tendon stem/progenitor cells. Stem Cells Dev, 2014-12-10;24(5):597-609. 2014-12-10 [PMID: 25351164] (Bioassay, Mouse) |
Bioassay |
Mouse |
Yang X, Trehan S, Guan Y, Sun C, Moore D, Jayasuriya C, Chen Q Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist. J Biol Chem, 2014-10-20;289(50):34768-79. 2014-10-20 [PMID: 25331953] (Bioassay, Chicken, Mouse) |
Bioassay |
Chicken, Mouse |
Park J, Jang S, Park D, Lim N, Deng C, Kim D, Green J, Kim H Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis. Mol Cancer Res, 2014-04-30;12(8):1088-99. 2014-04-30 [PMID: 24784840] (Bioassay, Mouse) |
Bioassay |
Mouse |
Shen , Jinhui, Nair , Ashwin, Saxena , Ramesh, Zhang , Cheng Ch, Borrelli , Joseph J, Tang , Liping Tissue engineering bone using autologous progenitor cells in the peritoneum. PLoS ONE, 2014-03-28;9(3):e93514. 2014-03-28 [PMID: 24681529] (Bioassay, Mouse) |
Bioassay |
Mouse |
Okamoto M, Udagawa N, Uehara S, Maeda K, Yamashita T, Nakamichi Y, Kato H, Saito N, Minami Y, Takahashi N, Kobayashi Y Noncanonical Wnt5a enhances Wnt/beta-catenin signaling during osteoblastogenesis. Sci Rep, 2014-03-27;4(0):4493. 2014-03-27 [PMID: 24670389] (Bioassay, Mouse) |
Bioassay |
Mouse |
Dussiot M, Maciel T, Fricot A, Chartier C, Negre O, Veiga J, Grapton D, Paubelle E, Payen E, Beuzard Y, Leboulch P, Ribeil J, Arlet J, Cote F, Courtois G, Ginzburg Y, Daniel T, Chopra R, Sung V, Hermine O, Moura I An activin receptor IIA ligand trap corrects ineffective erythropoiesis in beta-thalassemia. Nat Med, 2014-03-23;20(4):398-407. 2014-03-23 [PMID: 24658077] (Bioassay, Mouse) |
Bioassay |
Mouse |
Tanwar V, Bylund J, Hu J, Yan J, Walthall J, Mukherjee A, Heaton W, Wang W, Potet F, Rai M, Kupershmidt S, Knapik E, Hatzopoulos A Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway. Stem Cells, 2014-07-01;32(7):1774-88. 2014-07-01 [PMID: 24648383] (Bioassay, Mouse) |
Bioassay |
Mouse |
Heinonen A, Rahman M, Dogbevia G, Jakobi H, Wolfl S, Sprengel R, Schwaninger M Neuroprotection by rAAV-mediated gene transfer of bone morphogenic protein 7. BMC Neurosci, 2014-03-11;15(0):38. 2014-03-11 [PMID: 24618040] (Bioassay, Human) |
Bioassay |
Human |
Todaro M, Gaggianesi M, Catalano V, Benfante A, Iovino F, Biffoni M, Apuzzo T, Sperduti I, Volpe S, Cocorullo G, Gulotta G, Dieli F, De Maria R, Stassi G CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis. Cell Stem Cell, 2014-03-06;14(3):342-56. 2014-03-06 [PMID: 24607406] (Bioassay, Human) |
Bioassay |
Human |
Abdel Aziz M, Wassef M, Ahmed H, Rashed L, Mahfouz S, Aly M, Hussein R, Abdelaziz M The role of bone marrow derived-mesenchymal stem cells in attenuation of kidney function in rats with diabetic nephropathy. Diabetol Metab Syndr, 2014-03-09;6(1):34. 2014-03-09 [PMID: 24606996] (Bioassay, Mouse) |
Bioassay |
Mouse |
Gao X, Cao Y, Staloch D, Gonzales M, Aronson J, Chao C, Hellmich M, Ko T Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis. PLoS ONE, 2014-02-21;9(2):e89114. 2014-02-21 [PMID: 24586530] (Bioassay, Mouse) |
Bioassay |
Mouse |
Wolf S, Hagl B, Kappler R Identification of BMP2 as an epigenetically silenced growth inhibitor in rhabdomyosarcoma. Int J Oncol, 2014-02-27;44(5):1727-35. 2014-02-27 [PMID: 24585058] (Bioassay, Human) |
Bioassay |
Human |
Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells. BMC Cancer, 2014-02-20;14(0):113. 2014-02-20 [PMID: 24555435] (Bioassay, Mouse) |
Bioassay |
Mouse |
Ratnayake M, Ploger F, Santibanez-Koref M, Loughlin J Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. PLoS ONE, 2014-01-21;9(1):e86590. 2014-01-21 [PMID: 24466161] (Bioassay, Human) |
Bioassay |
Human |
Hang , Qinglei, Zhou , Ying, Hou , Sicong, Zhang , Dongmei, Yang , Xiaojing, Chen , Jianping, Ben , Zhiyun, Cheng , Chun, Shen , Aiguo Asparagine-linked glycosylation of bone morphogenetic protein-2 is required for secretion and osteoblast differentiation. Glycobiology, 2013-12-12;24(3):292-304. 2013-12-12 [PMID: 24336949] (Bioassay, Hamster) |
Bioassay |
Hamster |
Bizen N, Inoue T, Shimizu T, Tabu K, Kagawa T, Taga T A growth-promoting signaling component cyclin D1 in neural stem cells has antiastrogliogenic function to execute self-renewal. Stem Cells, 2014-06-01;32(6):1602-15. 2014-06-01 [PMID: 24302516] (Bioassay, Mouse) |
Bioassay |
Mouse |
Garrel G, Simon V, Denoyelle C, Ishaq M, Rouch C, Dairou J, Magnan C, Migrenne S, Cruciani-Guglielmacci C, Cohen-Tannoudji J Unsaturated fatty acids disrupt Smad signaling in gonadotrope cells leading to inhibition of FSHbeta gene expression. Endocrinology, 2013-11-18;155(2):592-604. 2013-11-18 [PMID: 24248462] (Bioassay, Rat) |
Bioassay |
Rat |
Clementi C, Tripurani S, Large M, Edson M, Creighton C, Hawkins S, Kovanci E, Kaartinen V, Lydon J, Pangas S, DeMayo F, Matzuk M Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans. PLoS Genet, 2013-11-14;9(11):e1003863. 2013-11-14 [PMID: 24244176] (Bioassay, Human) |
Bioassay |
Human |
Brady K, Dickinson S, Guillot P, Polak J, Blom A, Kafienah W, Hollander A Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis. Stem Cells Dev, 2013-12-04;23(5):541-54. 2013-12-04 [PMID: 24172175] (Bioassay, Human) |
Bioassay |
Human |
Gao L, Sheu T, Dong Y, Hoak D, Zuscik M, Schwarz E, Hilton M, O'Keefe R, Jonason J TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages. J Cell Sci, 2013-10-21;126(0):5704-13. 2013-10-21 [PMID: 24144697] (Bioassay, Mouse) |
Bioassay |
Mouse |
Kawamoto T, Kobayashi Y, Nakajima H, Yamagishi Y Generation of robust vascular networks from cardiovascular blast populations derived from human induced pluripotent stem cells in vivo and ex vivo organ culture system. Biochem Biophys Res Commun, 2013-10-16;441(1):180-5. 2013-10-16 [PMID: 24140407] (Bioassay, Mouse) |
Bioassay |
Mouse |
Laperrousaz B, Jeanpierre S, Sagorny K, Voeltzel T, Ramas S, Kaniewski B, Ffrench M, Salesse S, Nicolini F, Maguer-Satta V Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression. Blood, 2013-10-07;122(23):3767-77. 2013-10-07 [PMID: 24100446] (Bioassay, Human) |
Bioassay |
Human |
Aubert-Foucher E, Mayer N, Pasdeloup M, Pagnon A, Hartmann D, Mallein-Gerin F A unique tool to selectively detect the chondrogenic IIB form of human type II procollagen protein. Matrix Biol, 2013-09-17;34(0):80-8. 2013-09-17 [PMID: 24055103] (Bioassay, Human) |
Bioassay |
Human |
Hwang J, Jiang T, Kulkarni S, Faure N, Schaffhausen B Protein phosphatase 2A isoforms utilizing Abeta scaffolds regulate differentiation through control of Akt protein. J Biol Chem, 2013-09-19;288(44):32064-73. 2013-09-19 [PMID: 24052256] (Bioassay, Mouse) |
Bioassay |
Mouse |
Koskinen C, Persson E, Baldock P, Stenberg A, Bostrom I, Matozaki T, Oldenborg P, Lundberg P Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein alpha (SIRPalpha) signaling. J Biol Chem, 2013-08-29;288(41):29333-44. 2013-08-29 [PMID: 23990469] (Bioassay, Mouse) |
Bioassay |
Mouse |
An J, Ohn J, Song J, Yang J, Park H, Choi H, Kim S, Kim S, Park W, Shin C Changes of microRNA profile and microRNA-mRNA regulatory network in bones of ovariectomized mice. J Bone Miner Res, 2014-03-01;29(3):644-56. 2014-03-01 [PMID: 23929739] (Bioassay, Mouse) |
Bioassay |
Mouse |
Talavera-Adame , Dodanim, Gupta , Ankur, Kurtovic , Silvia, Chaiboonma , Kira L, Arumugaswami , Vaithili, Dafoe , Donald C Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation. Stem Cells Dev, 2013-09-24;22(24):3252-60. 2013-09-24 [PMID: 23924071] (Bioassay, Mouse) |
Bioassay |
Mouse |
Gadi , Jogeswar, Jung , Seung-Hy, Lee , Min-Jung, Jami , Ajita, Ruthala , Kalyani, Kim , Kyoung-M, Cho , Nam-Hoon, Jung , Han-Sung, Kim , Cheol-He, Lim , Sung-Kil The transcription factor protein Sox11 enhances early osteoblast differentiation by facilitating proliferation and the survival of mesenchymal and osteoblast progenitors. J Biol Chem, 2013-07-25;288(35):25400-13. 2013-07-25 [PMID: 23888050] (Bioassay, Mouse) |
Bioassay |
Mouse |
Deschaseaux F, Gaillard J, Langonne A, Chauveau C, Naji A, Bouacida A, Rosset P, Heymann D, De Pinieux G, Rouas-Freiss N, Sensebe L Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue. FASEB J, 2013-04-16;27(8):2977-87. 2013-04-16 [PMID: 23592762] (Bioassay, Human) |
Bioassay |
Human |
Wang , Yidong, Wu , Bingruo, Chamberlain , Alyssa A, Lui , Wendy, Koirala , Pratisth, Susztak , Katalin, Klein , Diana, Taylor , Verdon, Zhou , Bin Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development. PLoS ONE, 2013-04-01;8(4):e60244. 2013-04-01 [PMID: 23560082] (Bioassay, Mouse) |
Bioassay |
Mouse |
Li S, Meyer N, Quarto N, Longaker M Integration of multiple signaling regulates through apoptosis the differential osteogenic potential of neural crest-derived and mesoderm-derived Osteoblasts. PLoS ONE, 2013-03-25;8(3):e58610. 2013-03-25 [PMID: 23536803] (Bioassay, Mouse) |
Bioassay |
Mouse |
Glister C, Satchell L, Bathgate R, Wade J, Dai Y, Ivell R, Anand-Ivell R, Rodgers R, Knight P Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production. Proc Natl Acad Sci U S A, 2013-03-25;110(15):E1426-35. 2013-03-25 [PMID: 23530236] (Bioassay, Bovine) |
Bioassay |
Bovine |
Yamamoto-Shiraishi Y, Kuroiwa A Wnt and BMP signaling cooperate with Hox in the control of Six2 expression in limb tendon precursor. 2013-03-13;0(0):. 2013-03-13 [PMID: 23499659] (In Vivo, Mouse) |
In Vivo |
Mouse |
Huegel J, Mundy C, Sgariglia F, Nygren P, Billings P, Yamaguchi Y, Koyama E, Pacifici M Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses. Dev Biol, 2013-03-01;377(1):100-12. 2013-03-01 [PMID: 23458899] (Bioassay, Mouse) |
Bioassay |
Mouse |
Narayanan , Karthike, Schumacher , Karl M, Tasnim , Farah, Kandasamy , Karthike, Schumacher , Annegret, Ni , Ming, Gao , Shujun, Gopalan , Began, Zink , Daniele, Ying , Jackie Y Human embryonic stem cells differentiate into functional renal proximal tubular-like cells. Kidney Int, 2013-02-06;83(4):593-603. 2013-02-06 [PMID: 23389418] (Bioassay, Human) |
Bioassay |
Human |
Akiyama H, Otani M, Sato S, Toyosawa S, Furukawa S, Wakisaka S, Maeda T A novel adipokine C1q/TNF-related protein 1 (CTRP1) regulates chondrocyte proliferation and maturation through the ERK1/2 signaling pathway. Mol Cell Endocrinol, 2013-01-21;369(1):63-71. 2013-01-21 [PMID: 23348620] (Bioassay, Mouse) |
Bioassay |
Mouse |
Chen , Jiekai, Liu , He, Liu , Jing, Qi , Jing, Wei , Bei, Yang , Jiaqi, Liang , Hanquan, Chen , You, Chen , Jing, Wu , Yaran, Guo , Lin, Zhu , Jieying, Zhao , Xiangjie, Peng , Tianran, Zhang , Yixin, Chen , Shen, Li , Xuejia, Li , Dongwei, Wang , Tao, Pei , Duanqing H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet, 2012-12-02;45(1):34-42. 2012-12-02 [PMID: 23202127] (Bioassay, Mouse) |
Bioassay |
Mouse |
Wu , Qifang, Sun , Chia Chi, Lin , Herbert, Babitt , Jodie L Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs). PLoS ONE, 2012-09-27;7(9):e46307. 2012-09-27 [PMID: 23029472] (Surface Plasmon Resonance, Human) |
Surface Plasmon Resonance |
Human |
Bruce D, Macartney T, Yong W, Shou W, Sapkota G Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway. Cell Signal, 2012-07-07;24(11):1999-2006. 2012-07-07 [PMID: 22781750] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
Satomi-Kobayashi S, Kinugasa M, Kobayashi R, Hatakeyama K, Kurogane Y, Ishida T, Emoto N, Asada Y, Takai Y, Hirata K, Rikitake Y Osteoblast-like differentiation of cultured human coronary artery smooth muscle cells by bone morphogenetic protein endothelial cell precursor-derived regulator (BMPER). J Biol Chem, 2012-07-09;287(36):30336-45. 2012-07-09 [PMID: 22778264] (Bioassay, Human) |
Bioassay |
Human |
Kim M, Yoon S, Lee S Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion. PLoS ONE, 2012-04-13;7(4):e35100. 2012-04-13 [PMID: 22514712] (Binding Assay, Human) |
Binding Assay |
Human |
Asumda FZ, Chase PB Age-related changes in rat bone-marrow mesenchymal stem cell plasticity. BMC Cell Biol., 2011-10-12;12(0):44. 2011-10-12 [PMID: 21992089] (Bioassay, Rat) |
Bioassay |
Rat |
Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth. J. Biol. Chem., 2011-07-07;286(34):30034-46. 2011-07-07 [PMID: 21737454] (Surface Plasmon Resonance, Human, Mouse) |
Surface Plasmon Resonance |
Human, Mouse |
Geens M, Sermon KD Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cells. J. Assist. Reprod. Genet., 2011-02-12;0(0):. 2011-02-12 [PMID: 21318592] (Bioassay, Human) |
Bioassay |
Human |
Dalfino G, Simone S, Porreca S, Cosola C, Balestra C, Manno C, Schena FP, Grandaliano G, Pertosa G Bone morphogenetic protein-2 may represent the molecular link between oxidative stress and vascular stiffness in chronic kidney disease. Atherosclerosis, 2010-04-29;211(2):418-23. 2010-04-29 [PMID: 20537331] (Bioassay, Human) |
Bioassay |
Human |
Haupt LM, Murali S, Mun FK, Teplyuk N, Mei LF, Stein GS, van Wijnen AJ, Nurcombe V, Cool SM The heparan sulfate proteoglycan (HSPG) glypican-3 mediates commitment of MC3T3-E1 cells toward osteogenesis. J. Cell. Physiol., 2009-09-01;220(3):780-91. 2009-09-01 [PMID: 19479939] (Bioassay, Mouse) |
Bioassay |
Mouse |
Tanno T, Porayette P, Sripichai O, Noh SJ, Byrnes C, Bhupatiraju A, Lee YT, Goodnough JB, Harandi O, Ganz T, Paulson RF, Miller JL Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells. Blood, 2009-05-04;114(1):181-6. 2009-05-04 [PMID: 19414861] (Bioassay, Human) |
Bioassay |
Human |
Little SC, Mullins MC Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis. Nat. Cell Biol., 2009-04-19;11(5):637-43. 2009-04-19 [PMID: 19377468] (Bioassay, Zebrafish) |
Bioassay |
Zebrafish |
Shafer SL, Towler DA Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J. Mol. Cell. Cardiol., 2009-01-21;46(5):621-35. 2009-01-21 [PMID: 19344627] (Bioassay, Mouse) |
Bioassay |
Mouse |
Irie N, Takada Y, Watanabe Y, Matsuzaki Y, Naruse C, Asano M, Iwakura Y, Suda T, Matsuo K Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis. J. Biol. Chem., 2009-03-19;284(21):14637-44. 2009-03-19 [PMID: 19299512] (Bioassay, Mouse) |
Bioassay |
Mouse |
Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature, 2008-08-21;454(7207):1000-4. 2008-08-21 [PMID: 18719589] (Bioassay, Mouse) |
Bioassay |
Mouse |
Jeanpierre S, Nicolini FE, Kaniewski B, Dumontet C, Rimokh R, Puisieux A, Maguer-Satta V BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling. Blood, 2008-07-29;112(8):3154-63. 2008-07-29 [PMID: 18664625] (Bioassay, Human) |
Bioassay |
Human |
Sengle G, Ono RN, Lyons KM, Bachinger HP, Sakai LY A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J. Mol. Biol., 2008-07-02;381(4):1025-39. 2008-07-02 [PMID: 18621057] (ELISA (Capture), Surface Plasmon Resonance, Human) |
ELISA (Capture), Surface Plasmon Resonance |
Human |
Kane R, Godson C, O'Brien C Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol. Vis., 2008-06-20;14(0):1138-48. 2008-06-20 [PMID: 18587495] (Bioassay, Human) |
Bioassay |
Human |
Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell, 2008-06-05;2(6):602-12. 2008-06-05 [PMID: 18522853] (Bioassay, Human) |
Bioassay |
Human |
Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bachinger HP, Sakai LY Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J. Biol. Chem., 2008-03-13;283(20):13874-88. 2008-03-13 [PMID: 18339631] (Binding Assay, Surface Plasmon Resonance, Human) |
Binding Assay, Surface Plasmon Resonance |
Human |
Pi X, Ren R, Kelley R, Zhang C, Moser M, Bohil AB, Divito M, Cheney RE, Patterson C Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors. J. Cell Biol., 2007-12-24;179(7):1569-82. 2007-12-24 [PMID: 18158328] (Bioassay, Mouse) |
Bioassay |
Mouse |
Hocking JC, Hehr CL, Chang RY, Johnston J, McFarlane S TGFbeta ligands promote the initiation of retinal ganglion cell dendrites in vitro and in vivo. Mol. Cell. Neurosci., 2007-10-05;37(2):247-60. 2007-10-05 [PMID: 17997109] (Bioassay, Xenopus) |
Bioassay |
Xenopus |
Southwood M, Jeffery TK, Yang X, Upton PD, Hall SM, Atkinson C, Haworth SG, Stewart S, Reynolds PN, Long L, Trembath RC, Morrell NW Regulation of bone morphogenetic protein signalling in human pulmonary vascular development. J. Pathol., 2008-01-01;214(1):85-95. 2008-01-01 [PMID: 17992660] (Bioassay, Human) |
Bioassay |
Human |
Wen Z, Han L, Bamburg JR, Shim S, Ming GL, Zheng JQ BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin. J. Cell Biol., 2007-07-02;178(1):107-19. 2007-07-02 [PMID: 17606869] (Bioassay, Xenopus) |
Bioassay |
Xenopus |
Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature, 2007-06-27;448(7150):196-9. 2007-06-27 [PMID: 17597760] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, Toyama Y, Tada N Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction. J. Immunol., 2007-07-01;179(1):639-46. 2007-07-01 [PMID: 17579086] (Bioassay, Mouse) |
Bioassay |
Mouse |
Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood, 2007-05-31;110(6):2182-9. 2007-05-31 [PMID: 17540841] (Bioassay, Mouse) |
Bioassay |
Mouse |
Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, Korb A, Smolen J, Hoffmann M, Scheinecker C, van der Heide D, Landewe R, Lacey D, Richards WG, Schett G Dickkopf-1 is a master regulator of joint remodeling. Nat. Med., 2007-01-21;13(2):156-63. 2007-01-21 [PMID: 17237793] (Bioassay, Mouse) |
Bioassay |
Mouse |
Ungefroren H, Schniewind B, Groth S, Chen WB, Muerkoster SS, Kalthoff H, Fandrich F Antitumor activity of ALK1 in pancreatic carcinoma cells. Int. J. Cancer, 2007-04-15;120(8):1641-51. 2007-04-15 [PMID: 17230504] (Bioassay, Human) |
Bioassay |
Human |
Zhu J, Garrett R, Jung Y, Zhang Y, Kim N, Wang J, Joe GJ, Hexner E, Choi Y, Taichman RS, Emerson SG Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood, 2007-01-16;109(9):3706-12. 2007-01-16 [PMID: 17227831] (Bioassay, Mouse) |
Bioassay |
Mouse |
Gossrau G, Thiele J, Konang R, Schmandt T, Brustle O Bone morphogenetic protein-mediated modulation of lineage diversification during neural differentiation of embryonic stem cells. Stem Cells, 2007-01-11;25(4):939-49. 2007-01-11 [PMID: 17218404] (Bioassay, Mouse) |
Bioassay |
Mouse |
Yao Y, Zebboudj AF, Torres A, Shao E, Bostrom K Activin-like kinase receptor 1 (ALK1) in atherosclerotic lesions and vascular mesenchymal cells. Cardiovasc. Res., 2006-09-27;74(2):279-89. 2006-09-27 [PMID: 17074310] (Bioassay, Bovine, Human) |
Bioassay |
Bovine, Human |
Bartunek J, Croissant JD, Wijns W, Gofflot S, de Lavareille A, Vanderheyden M, Kaluzhny Y, Mazouz N, Willemsen P, Penicka M, Mathieu M, Homsy C, De Bruyne B, McEntee K, Lee IW, Heyndrickx GR Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium. Am. J. Physiol. Heart Circ. Physiol., 2006-10-20;292(2):H1095-104. 2006-10-20 [PMID: 17056665] (Bioassay, Canine, Human) |
Bioassay |
Canine, Human |
Bonafede A, Kohler T, Rodriguez-Niedenfuhr M, Brand-Saberi B BMPs restrict the position of premuscle masses in the limb buds by influencing Tcf4 expression. Dev. Biol., 2006-06-15;299(2):330-44. 2006-06-15 [PMID: 17005177] (In Vivo, Chicken) |
In Vivo |
Chicken |
Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells. Arthritis Res. Ther., 2006-01-01;8(5):R146. 2006-01-01 [PMID: 16945157] (Bioassay, Mouse) |
Bioassay |
Mouse |
Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development, 2006-08-30;133(19):3787-96. 2006-08-30 [PMID: 16943279] (Bioassay, Mouse) |
Bioassay |
Mouse |
Liu HW, Chen CH, Tsai CL, Hsiue GH Targeted delivery system for juxtacrine signaling growth factor based on rhBMP-2-mediated carrier-protein conjugation. Bone, 2006-06-16;39(4):825-36. 2006-06-16 [PMID: 16782421] (In Vivo, Rabbit) |
In Vivo |
Rabbit |
Schlueter J, Manner J, Brand T BMP is an important regulator of proepicardial identity in the chick embryo. Dev. Biol., 2006-04-01;295(2):546-58. 2006-04-01 [PMID: 16677627] (Bioassay, Chicken) |
Bioassay |
Chicken |
Maeshima A, Vaughn DA, Choi Y, Nigam SK Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct. Dev. Biol., 2006-04-27;295(2):473-85. 2006-04-27 [PMID: 16643884] (Bioassay, Rat) |
Bioassay |
Rat |
Hong SJ, Kim CS, Han DK, Cho IH, Jung UW, Choi SH, Kim CK, Cho KS The effect of a fibrin-fibronectin/beta-tricalcium phosphate/recombinant human bone morphogenetic protein-2 system on bone formation in rat calvarial defects. Biomaterials, 2006-03-29;27(20):3810-6. 2006-03-29 [PMID: 16574220] (In Vivo, Rat) |
In Vivo |
Rat |
Blair DG, Plisov S, Vasiliev G, Perantoni AO, Athanasiou M, Wu JY, Oppenheim JJ Cutting edge: bone morphogenetic protein antagonists Drm/Gremlin and Dan interact with Slits and act as negative regulators of monocyte chemotaxis. J. Immunol., 2004-11-15;173(10):5914-7. 2004-11-15 [PMID: 15528323] (Bioassay, Human) |
Bioassay |
Human |
Knosp WM, Scott V, Bachinger HP, Stadler HS HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesis. Development, 2004-09-01;131(18):4581-92. 2004-09-01 [PMID: 15342482] (In Vivo, Mouse) |
In Vivo |
Mouse |
Binnerts ME, Wen X, Cante-Barrett K, Bright J, Chen HT, Asundi V, Sattari P, Tang T, Boyle B, Funk W, Rupp F Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins. Biochem. Biophys. Res. Commun., 2004-03-05;315(2):272-80. 2004-03-05 [PMID: 14766204] (Bioassay, Mouse) |
Bioassay |
Mouse |
Moser M, Binder O, Wu Y, Aitsebaomo J, Ren R, Bode C, Bautch VL, Conlon FL, Patterson C BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol. Cell. Biol., 2003-08-01;23(16):5664-79. 2003-08-01 [PMID: 12897139] (Bioassay, Mouse) |
Bioassay |
Mouse |
Lee YM, Nam SH, Seol YJ, Kim TI, Lee SJ, Ku Y, Rhyu IC, Chung CP, Han SB, Choi SM Enhanced bone augmentation by controlled release of recombinant human bone morphogenetic protein-2 from bioabsorbable membranes. J. Periodontol., 2003-06-01;74(6):865-72. 2003-06-01 [PMID: 12886998] (Bioassay, Rabbit) |
Bioassay |
Rabbit |
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