MCG10 Antibody - BSA Free

MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IP.

Showing Publications 1 - 2 of 2.

Publications using NBP1-76729	Applications	Species
Yanatori I, Richardson DR, Toyokuni S, Kishi F. The Iron Chaperone Poly (rC)-binding Protein 2 Forms a Metabolon with the Heme Oxygenase 1/Cytochrome P450 Reductase Complex for Heme Catabolism and Iron Transfer J. Biol. Chem. 2017-06-27 [PMID: 28655775] (Human)		Human
Yanatori I, Richardson DR, Imada K, Kishi F. Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2. J Biol Chem 2016-08-12 [PMID: 27302059] (IP)	IP

Array NBP1-76729

• MCG10 Antibodies
• MCG10 Lysates
• MCG10 Proteins