Prohibitin 2 Antibody

REA (repressor of estrogen receptor activity), also known as prohibitin 2, has been shown to exhibit a variety of functions that includes mitochondrial chaperone activity, cell cycle regulation, and transcriptional regulation. REA localizes to the mitochondria and associates with mitochondrial complex I where it may play a role in mitochondrial metabolism. REA interacts with pRb to inhibit E2F-mediated transcription as well as the estrogen receptor to repress estrogen-dependent transcription via recruitment of histone deacetylases. Alternate names for REA include B-cell receptor-associated protein BAP37, D-prohibitin, PHB2, BAP, p22, BCAP37, PNAS-141, and MGC117268.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IP, WB.

Showing Publications 1 - 2 of 2.

Publications using NB100-1809	Applications	Species
Begum A, Lin Q, Yu C, Yun Z. Interaction of delta-like 1 homolog (Drosophila) with prohibitins and its impact on tumor cell clonogenicity. Mol. Cancer Res. 2014-01-01 [PMID: 24249679] (IP, WB, Human)	IP, WB	Human
Heidler J, Al-Furoukh N, Kukat C et al. NOA1 is necessary for oxygen-dependent regulation of mitochondrial respiratory complexes. J Biol Chem. 2011-07-19 [PMID: 21771794]

Array NB100-1809

• Prohibitin 2 Antibodies
• Prohibitin 2 Lysates
• Prohibitin 2 Proteins