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Podocin/NPHS2 Antibody [DyLight 594]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 594

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Podocin/NPHS2 Antibody [DyLight 594] Summary

Immunogen
Partial recombinant protein made to an internal portion of human Podocin/NPHS2 (between amino acids 250-400) [UniProt Q9NP85].
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NPHS2
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Podocin/NPHS2 Antibody [DyLight 594]

  • Nephrosis 2
  • nephrosis 2, idiopathic, steroid-resistant (podocin)
  • NPHS2
  • PDCN
  • PDCNSRN1podocin
  • Podocin
  • SRN1

Background

NPHS2 encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Podocin/NPHS2 Antibody (NBP3-18129DL594) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NPHS2