PEDFR/PNPLA2/ATGL Antibody (494702)

Images

 
Y‑79 human retinoblastoma cell line was stained with Mouse Anti-Human PEDF R/PNPLA2 Monoclonal Antibody (Catalog # MAB5387, filled histogram) or isotype control anti­body (Catalog # MAB0041, open histogram), ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
494702
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

PEDFR/PNPLA2/ATGL Antibody (494702) Summary

Immunogen
E. coli-derived recombinant human PEDF R/PNPLA2
Val162-Thr332
Accession # Q96AD5
Specificity
Detects human PEDF R/PNPLA2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse PEDF R is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PNPLA2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 1 ug/mL
Publications
Read Publication using
MAB5387 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PEDFR/PNPLA2/ATGL Antibody (494702)

  • Adipose triglyceride lipase
  • ATGL
  • ATGL1110001C14Rik
  • Calcium-independent phospholipase A2
  • Desnutrin
  • EC 3.1.1.3
  • FP17548
  • IPLA2-zeta
  • patatin-like phospholipase domain containing 2
  • patatin-like phospholipase domain-containing protein 2
  • patatin-like phospholipase domain-containing protein 2-like
  • PEDF R
  • PEDFR
  • PEDF-R
  • Pigment epithelium-derived factor
  • PNPLA2
  • Transport-secretion protein 2
  • transport-secretion protein 2.2
  • triglyceride hydrolase
  • TTS2
  • TTS2.2
  • TTS-2.2
  • TTS2DKFZp667M109

Background

PEDF R (pigment epithelium-derived factor receptor) is also called ATGL (adipose triglyceride lipase), TTS2 (transport-secretion protein 2), iPLA2 zeta (calcium-independent phospholipase A2 zeta) or desnutrin. It is a 54 kDa transmembrane protein that is member 2 of the patatin-like phospholipase domain-containing protein family (gene name PNPLA2). PEDF is highly expressed in adipose tissue, where it catalyzes formation of diacyglycerol from triglyceride. It has also been found in the retina (as a receptor for PEDF), testis, cardiac and skeletal muscle. Human PEDF R shares 85% amino acid (aa) identity with mouse and rat PEDF R within aa 162‑332, the region used as an immunogen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PEDFR/PNPLA2/ATGL Antibody (MAB5387)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: IHC-Fr, Western Blot.


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(1)
Western Blot
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Bioinformatics

Gene Symbol PNPLA2
Uniprot